STRINGSTRING
col1a2 col1a2 lrp6 lrp6 ptk2 ptk2 wnt3a wnt3a pik3c3 pik3c3 acp5 acp5 sost sost gsk3b gsk3b tgfb3 tgfb3 fgf23 fgf23 H2MLW1_ORYLA H2MLW1_ORYLA LOC101167033 LOC101167033 lum lum dcn dcn p3h3 p3h3 sparc sparc runx2 runx2 LOC101155815 LOC101155815 sox9 sox9 LOC101168720 LOC101168720 SRC SRC sp7 sp7 LOC101155037 LOC101155037 LOC101157631 LOC101157631 LOC101160344 LOC101160344 sema3a sema3a wnt1 wnt1 LOC101164480 LOC101164480
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
col1a2Collagen, type I, alpha 2. (1356 aa)
lrp6Low-density lipoprotein receptor-related protein; Component of the Wnt-Fzd-LRP5-LRP6 complex that triggers beta-catenin signaling through inducing aggregation of receptor-ligand complexes into ribosome-sized signalsomes. Belongs to the LDLR family. (1623 aa)
ptk2Protein tyrosine kinase 2ab; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1119 aa)
wnt3aProtein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
pik3c3Phosphatidylinositol 3-kinase catalytic subunit type 3. (884 aa)
acp5Tartrate-resistant acid phosphatase type 5. (357 aa)
sostSclerostin. (219 aa)
gsk3bGlycogen synthase kinase 3 beta, genome duplicate a. (216 aa)
tgfb3Transforming growth factor beta; Belongs to the TGF-beta family. (405 aa)
fgf23Fibroblast growth factor 23; Belongs to the heparin-binding growth factors family. (263 aa)
H2MLW1_ORYLAUncharacterized protein. (125 aa)
LOC101167033Zgc:113307. (366 aa)
lumLumican. (342 aa)
dcnDecorin; May affect the rate of fibrils formation. (367 aa)
p3h3Prolyl 3-hydroxylase 3. (732 aa)
sparcOsteonectin. (298 aa)
runx2Runt-related transcription factor. (461 aa)
LOC101155815Transforming growth factor beta; Belongs to the TGF-beta family. (408 aa)
sox9HMG box domain-containing protein. (476 aa)
LOC101168720Glycogen synthase kinase 3 alpha a; Belongs to the protein kinase superfamily. (438 aa)
SRCTyrosine-protein kinase. (544 aa)
sp7Sp7 transcription factor. (460 aa)
LOC101155037Transforming growth factor beta; Belongs to the TGF-beta family. (420 aa)
LOC101157631Transforming growth factor beta; Belongs to the TGF-beta family. (444 aa)
LOC101160344Glycogen synthase kinase 3 alpha b; Belongs to the protein kinase superfamily. (480 aa)
sema3aSema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3Ab; Belongs to the semaphorin family. (796 aa)
wnt1Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (398 aa)
LOC101164480Tyrosine-protein kinase. (551 aa)
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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