14 items (Oryzias latipes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	fgf20a	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (252 aa)
	fgf10	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (250 aa)
	crbn	Cereblon. (447 aa)
	actb	Actin, cytoplasmic 1. (434 aa)
	ikzf1	IKAROS family zinc finger 1 (Ikaros). (628 aa)
	sall4	Spalt-like transcription factor 4. (1059 aa)
	cyp1a	Cytochrome P450 1A1; Cytochromes P450 are a group of heme-thiolate monooxygenases. They oxidize a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. (521 aa)
	shh	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (414 aa)
	LOC101168921	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA. (410 aa)
	tbx5	Uncharacterized protein. (536 aa)
	fgf16	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (217 aa)
	LOC101154851	Cullin 4A; Belongs to the cullin family. (612 aa)
	cul4b	Cullin 4B; Belongs to the cullin family. (845 aa)
	fgf4	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (188 aa)

Your Current Organism:

Oryzias latipes

NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

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a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC101154851	crbn	ENSORLP00000005815	ENSORLP00000040704	Cullin 4A; Belongs to the cullin family.	Cereblon.	0.934
LOC101154851	cul4b	ENSORLP00000005815	ENSORLP00000001369	Cullin 4A; Belongs to the cullin family.	Cullin 4B; Belongs to the cullin family.	0.917
LOC101168921	cyp1a	ENSORLP00000011676	ENSORLP00000018073	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	Cytochrome P450 1A1; Cytochromes P450 are a group of heme-thiolate monooxygenases. They oxidize a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.	0.451
actb	cyp1a	ENSORLP00000031145	ENSORLP00000018073	Actin, cytoplasmic 1.	Cytochrome P450 1A1; Cytochromes P450 are a group of heme-thiolate monooxygenases. They oxidize a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.	0.451
crbn	LOC101154851	ENSORLP00000040704	ENSORLP00000005815	Cereblon.	Cullin 4A; Belongs to the cullin family.	0.934
crbn	cul4b	ENSORLP00000040704	ENSORLP00000001369	Cereblon.	Cullin 4B; Belongs to the cullin family.	0.914
crbn	ikzf1	ENSORLP00000040704	ENSORLP00000028454	Cereblon.	IKAROS family zinc finger 1 (Ikaros).	0.778
crbn	sall4	ENSORLP00000040704	ENSORLP00000020188	Cereblon.	Spalt-like transcription factor 4.	0.729
cul4b	LOC101154851	ENSORLP00000001369	ENSORLP00000005815	Cullin 4B; Belongs to the cullin family.	Cullin 4A; Belongs to the cullin family.	0.917
cul4b	crbn	ENSORLP00000001369	ENSORLP00000040704	Cullin 4B; Belongs to the cullin family.	Cereblon.	0.914
cyp1a	LOC101168921	ENSORLP00000018073	ENSORLP00000011676	Cytochrome P450 1A1; Cytochromes P450 are a group of heme-thiolate monooxygenases. They oxidize a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.	Actin, cytoplasmic 1, N-terminally processed; Actin is a highly conserved protein that polymerizes to produce filaments that form cross-linked networks in the cytoplasm of cells. Actin exists in both monomeric (G-actin) and polymeric (F-actin) forms, both forms playing key functions, such as cell motility and contraction. In addition to their role in the cytoplasmic cytoskeleton, G- and F-actin also localize in the nucleus, and regulate gene transcription and motility and repair of damaged DNA.	0.451
cyp1a	actb	ENSORLP00000018073	ENSORLP00000031145	Cytochrome P450 1A1; Cytochromes P450 are a group of heme-thiolate monooxygenases. They oxidize a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics.	Actin, cytoplasmic 1.	0.451
fgf10	fgf16	ENSORLP00000040733	ENSORLP00000007650	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.405
fgf10	fgf20a	ENSORLP00000040733	ENSORLP00000042676	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.439
fgf10	fgf4	ENSORLP00000040733	ENSORLP00000000362	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.615
fgf10	shh	ENSORLP00000040733	ENSORLP00000013115	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.597
fgf16	fgf10	ENSORLP00000007650	ENSORLP00000040733	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.405
fgf16	fgf4	ENSORLP00000007650	ENSORLP00000000362	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.478
fgf20a	fgf10	ENSORLP00000042676	ENSORLP00000040733	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.439
fgf20a	fgf4	ENSORLP00000042676	ENSORLP00000000362	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.506