STRINGSTRING
fndc5 fndc5 arhgef10l arhgef10l ARHGEF25 ARHGEF25 arhgef25 arhgef25 lepa lepa lpar1 lpar1 col1a2 col1a2 arhgef12 arhgef12 arhgef37 arhgef37 stk40 stk40 fgf10 fgf10 PPP2R5C PPP2R5C akap6 akap6 lamc3 lamc3 pkdcc pkdcc arfgef1 arfgef1 pparg pparg ARHGEF17 ARHGEF17 Lama5 Lama5 rxra rxra Col27a1 Col27a1 il17rb il17rb Akap13 Akap13 arhgef6 arhgef6 rptor rptor map3k5 map3k5 ENSORLP00000029534 ENSORLP00000029534 pax3 pax3 LOC101155573 LOC101155573 PTEN PTEN H2MZJ3_ORYLA H2MZJ3_ORYLA ccn2 ccn2 col4a1 col4a1 lama4 lama4 gata4 gata4 EIF2AK4 EIF2AK4 prkcq prkcq tgfb3 tgfb3 myog myog Col5a2 Col5a2 sirt1 sirt1 LOC101157143 LOC101157143 CDC42 CDC42 LOC101162553 LOC101162553 Col24a1 Col24a1 col9a1 col9a1 Col19a1 Col19a1 lamb3 lamb3 H2LZX2_ORYLA H2LZX2_ORYLA LOC101155815 LOC101155815 rgma rgma creb5 creb5 LOC100125506 LOC100125506 pten pten LOC101161650 LOC101161650 LOC101164656 LOC101164656 pax5 pax5 pkn2 pkn2 paxbp1 paxbp1 pdgfrb pdgfrb npy npy pax7 pax7 LOC101155530 LOC101155530 zfpm2 zfpm2 bmpr2 bmpr2 LOC101155037 LOC101155037 LOC101158789 LOC101158789 arfgef2 arfgef2 FGF13 FGF13 Fgf1 Fgf1 LOC101157631 LOC101157631 ppp2ca ppp2ca COL14A1 COL14A1 lamb1 lamb1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
fndc5Fibronectin type III domain containing 5. (226 aa)
arhgef10lRho guanine nucleotide exchange factor (GEF) 10-like a. (1222 aa)
ARHGEF25Uncharacterized protein. (729 aa)
arhgef25Rho guanine nucleotide exchange factor (GEF) 25b. (715 aa)
lepaLeptin-A; May function as part of a signaling pathway that acts to regulate the size of the body fat depot. (185 aa)
lpar1Lysophosphatidic acid receptor 1; Belongs to the G-protein coupled receptor 1 family. (352 aa)
col1a2Collagen, type I, alpha 2. (1356 aa)
arhgef12Rho guanine nucleotide exchange factor (GEF) 12a. (1434 aa)
arhgef37Rho guanine nucleotide exchange factor (GEF) 37. (776 aa)
stk40Serine/threonine kinase 40. (442 aa)
fgf10Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (250 aa)
PPP2R5CSerine/threonine protein phosphatase 2A regulatory subunit; Belongs to the phosphatase 2A regulatory subunit. (567 aa)
akap6A kinase (PRKA) anchor protein 6. (2292 aa)
lamc3Laminin, gamma 3. (1645 aa)
pkdccProtein kinase domain containing, cytoplasmic b. (473 aa)
arfgef1ADP-ribosylation factor guanine nucleotide-exchange factor 1 (brefeldin A-inhibited). (1920 aa)
ppargUncharacterized protein. (549 aa)
ARHGEF17Rho guanine nucleotide exchange factor (GEF) 17. (2556 aa)
Lama5Uncharacterized protein. (113 aa)
rxraRetinoid X receptor, alpha a. (495 aa)
Col27a1LAM_G_DOMAIN domain-containing protein. (228 aa)
il17rbSEFIR domain-containing protein. (434 aa)
Akap13ANK_REP_REGION domain-containing protein. (1338 aa)
arhgef6Rac/Cdc42 guanine nucleotide exchange factor (GEF) 6. (764 aa)
rptorRegulatory associated protein of MTOR, complex 1. (1372 aa)
map3k5Mitogen-activated protein kinase kinase kinase 5. (1350 aa)
ENSORLP00000029534FYVE, RhoGEF and PH domain containing 1. (457 aa)
pax3Paired box 3b. (496 aa)
LOC101155573DLC1 Rho GTPase activating protein. (1850 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (415 aa)
H2MZJ3_ORYLALaminin, alpha 5. (1622 aa)
ccn2Cellular communication network factor 2a. (346 aa)
col4a1Collagen IV NC1 domain-containing protein. (1639 aa)
lama4Laminin, alpha 4. (1873 aa)
gata4GATA binding protein 4. (388 aa)
EIF2AK4Eukaryotic translation initiation factor 2 alpha kinase 4. (1653 aa)
prkcqProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (692 aa)
tgfb3Transforming growth factor beta; Belongs to the TGF-beta family. (405 aa)
myogMyogenin. (248 aa)
Col5a2Collagen, type V, alpha 2a. (930 aa)
sirt1Deacetylase sirtuin-type domain-containing protein. (680 aa)
LOC101157143Protein kinase N3. (928 aa)
CDC42Cell division cycle 42. (191 aa)
LOC101162553Collagen, type VI, alpha 2. (1024 aa)
Col24a1LAM_G_DOMAIN domain-containing protein. (669 aa)
col9a1Collagen, type IX, alpha 1b. (629 aa)
Col19a1LAM_G_DOMAIN domain-containing protein. (391 aa)
lamb3Uncharacterized protein. (1255 aa)
H2LZX2_ORYLACollagen, type IV, alpha 6. (1088 aa)
LOC101155815Transforming growth factor beta; Belongs to the TGF-beta family. (408 aa)
rgmaRepulsive guidance molecule BMP co-receptor a. (444 aa)
creb5cAMP responsive element binding protein 5b. (512 aa)
LOC100125506Retinoid x receptor, beta b. (444 aa)
ptenPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (437 aa)
LOC101161650Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (157 aa)
LOC101164656Procollagen, type IX, alpha 2. (583 aa)
pax5Paired box 5. (396 aa)
pkn2Protein kinase N2. (975 aa)
paxbp1PAX3 and PAX7 binding protein 1. (917 aa)
pdgfrbPlatelet-derived growth factor receptor, beta polypeptide; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1112 aa)
npyUncharacterized protein. (133 aa)
pax7Uncharacterized protein. (524 aa)
LOC101155530Procollagen, type V, alpha 1. (1501 aa)
zfpm2Zinc finger protein, FOG family member 2a. (1170 aa)
bmpr2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1056 aa)
LOC101155037Transforming growth factor beta; Belongs to the TGF-beta family. (420 aa)
LOC101158789Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (251 aa)
arfgef2ADP-ribosylation factor guanine nucleotide-exchange factor 2 (brefeldin A-inhibited). (1836 aa)
FGF13Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (255 aa)
Fgf1Multifunctional fusion protein; Plays an important role in the regulation of cell survival, cell division, angiogenesis, cell differentiation and cell migration. Functions as potent mitogen in vitro. Acts as a ligand for FGFR1 and integrins. Binds to FGFR1 in the presence of heparin leading to FGFR1 dimerization and activation via sequential autophosphorylation on tyrosine residues which act as docking sites for interacting proteins, leading to the activation of several signaling cascades. Binds to integrins. Its binding to integrins and subsequent ternary complex formation with integr [...] (159 aa)
LOC101157631Transforming growth factor beta; Belongs to the TGF-beta family. (444 aa)
ppp2caSerine/threonine-protein phosphatase. (309 aa)
COL14A1Collagen type XIV alpha 1 chain. (1869 aa)
lamb1Laminin, beta 1a. (1808 aa)
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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