31 items (Oryzias latipes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSORLP00000033948	Homeobox A5a. (302 aa)
	LOC101164012	Homeobox B6b. (251 aa)
	wnt11	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
	sod2	Superoxide dismutase; Destroys radicals which are normally produced within the cells and which are toxic to biological systems. Belongs to the iron/manganese superoxide dismutase family. (226 aa)
	bmp4	Bone morphogenetic protein 4. (441 aa)
	cyp1a	Cytochrome P450 1A1; Cytochromes P450 are a group of heme-thiolate monooxygenases. They oxidize a variety of structurally unrelated compounds, including steroids, fatty acids, and xenobiotics. (521 aa)
	cyp26a1	Cytochrome P450 26A1; Belongs to the cytochrome P450 family. (488 aa)
	LOC101160930	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (507 aa)
	dhrs3	Dehydrogenase/reductase (SDR family) member 3b; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (318 aa)
	aldh3b1	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (477 aa)
	gata4	GATA binding protein 4. (388 aa)
	LOC101167262	Uncharacterized protein; Belongs to the ATP:guanido phosphotransferase family. (381 aa)
	LOC101159441	Axin 2 (conductin, axil). (841 aa)
	pik3c3	Phosphatidylinositol 3-kinase catalytic subunit type 3. (884 aa)
	AXIN2	Axin 2. (791 aa)
	LOC101169907	Uncharacterized protein; Belongs to the ATP:guanido phosphotransferase family. (408 aa)
	pparg	Uncharacterized protein. (549 aa)
	LOC101155494	Uncharacterized protein. (883 aa)
	LOC101166239	Creatine kinase, muscle a; Belongs to the ATP:guanido phosphotransferase family. (381 aa)
	hoxb5	Homeobox B5b. (281 aa)
	CKB	Creatine kinase B; Belongs to the ATP:guanido phosphotransferase family. (407 aa)
	LOC101164721	Creatine kinase, mitochondrial 1A; Belongs to the ATP:guanido phosphotransferase family. (417 aa)
	CKM	Uncharacterized protein; Belongs to the ATP:guanido phosphotransferase family. (421 aa)
	LOC101156839	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (499 aa)
	CKMT2	Creatine kinase, mitochondrial 2; Belongs to the ATP:guanido phosphotransferase family. (414 aa)
	LOC101159505	Titin-cap (telethonin). (179 aa)
	axin1	Axin 1. (854 aa)
	tp53	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression (By similarity); Belongs to the p53 family. (352 aa)
	LOC101157544	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family. (497 aa)
	sox9	HMG box domain-containing protein. (476 aa)
	tbx5	Uncharacterized protein. (536 aa)

Your Current Organism:

Oryzias latipes

NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AXIN2	LOC101155494	ENSORLP00000035131	ENSORLP00000038069	Axin 2.	Uncharacterized protein.	0.668
AXIN2	LOC101159441	ENSORLP00000035131	ENSORLP00000011155	Axin 2.	Axin 2 (conductin, axil).	0.552
AXIN2	axin1	ENSORLP00000035131	ENSORLP00000006039	Axin 2.	Axin 1.	0.667
CKB	LOC101166239	ENSORLP00000000553	ENSORLP00000038248	Creatine kinase B; Belongs to the ATP:guanido phosphotransferase family.	Creatine kinase, muscle a; Belongs to the ATP:guanido phosphotransferase family.	0.488
ENSORLP00000033948	LOC101164012	ENSORLP00000033948	ENSORLP00000015504	Homeobox A5a.	Homeobox B6b.	0.438
ENSORLP00000033948	hoxb5	ENSORLP00000033948	ENSORLP00000039816	Homeobox A5a.	Homeobox B5b.	0.491
LOC101155494	AXIN2	ENSORLP00000038069	ENSORLP00000035131	Uncharacterized protein.	Axin 2.	0.668
LOC101155494	LOC101159441	ENSORLP00000038069	ENSORLP00000011155	Uncharacterized protein.	Axin 2 (conductin, axil).	0.675
LOC101155494	axin1	ENSORLP00000038069	ENSORLP00000006039	Uncharacterized protein.	Axin 1.	0.552
LOC101155494	tp53	ENSORLP00000038069	ENSORLP00000008031	Uncharacterized protein.	Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression (By similarity); Belongs to the p53 family.	0.489
LOC101157544	aldh3b1	ENSORLP00000009311	ENSORLP00000021684	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	Aldehyde dehydrogenase; Belongs to the aldehyde dehydrogenase family.	0.904
LOC101159441	AXIN2	ENSORLP00000011155	ENSORLP00000035131	Axin 2 (conductin, axil).	Axin 2.	0.552
LOC101159441	LOC101155494	ENSORLP00000011155	ENSORLP00000038069	Axin 2 (conductin, axil).	Uncharacterized protein.	0.675
LOC101159441	axin1	ENSORLP00000011155	ENSORLP00000006039	Axin 2 (conductin, axil).	Axin 1.	0.676
LOC101164012	ENSORLP00000033948	ENSORLP00000015504	ENSORLP00000033948	Homeobox B6b.	Homeobox A5a.	0.438
LOC101164012	hoxb5	ENSORLP00000015504	ENSORLP00000039816	Homeobox B6b.	Homeobox B5b.	0.802
LOC101166239	CKB	ENSORLP00000038248	ENSORLP00000000553	Creatine kinase, muscle a; Belongs to the ATP:guanido phosphotransferase family.	Creatine kinase B; Belongs to the ATP:guanido phosphotransferase family.	0.488
LOC101166239	LOC101167262	ENSORLP00000038248	ENSORLP00000025241	Creatine kinase, muscle a; Belongs to the ATP:guanido phosphotransferase family.	Uncharacterized protein; Belongs to the ATP:guanido phosphotransferase family.	0.488
LOC101166239	LOC101169907	ENSORLP00000038248	ENSORLP00000036138	Creatine kinase, muscle a; Belongs to the ATP:guanido phosphotransferase family.	Uncharacterized protein; Belongs to the ATP:guanido phosphotransferase family.	0.513
LOC101167262	LOC101166239	ENSORLP00000025241	ENSORLP00000038248	Uncharacterized protein; Belongs to the ATP:guanido phosphotransferase family.	Creatine kinase, muscle a; Belongs to the ATP:guanido phosphotransferase family.	0.488