15 items (Oryzias latipes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC101160196	Ephrin-B3a; Belongs to the ephrin family. (340 aa)
	fgf3	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (245 aa)
	vegfc	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family. (494 aa)
	nrp2	Neuropilin; Belongs to the neuropilin family. (910 aa)
	nkx2-3	NK2 homeobox 3. (341 aa)
	LOC100049417	Hairy-related 5. (175 aa)
	shh	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development. (414 aa)
	LOC101159747	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (389 aa)
	wnt4	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (355 aa)
	pax1	Paired-box transcription factor pax1. (356 aa)
	egf	Epidermal growth factor. (966 aa)
	foxi2	Forkhead box i1. (377 aa)
	nrp1	Neuropilin; Belongs to the neuropilin family. (938 aa)
	fgf8	Fibroblast growth factor; Belongs to the heparin-binding growth factors family. (214 aa)
	sema3d	Sema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3D; Belongs to the semaphorin family. (792 aa)

Your Current Organism:

Oryzias latipes

NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC101159747	fgf3	ENSORLP00000015020	ENSORLP00000000370	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.422
LOC101159747	fgf8	ENSORLP00000015020	ENSORLP00000042553	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.432
egf	fgf3	ENSORLP00000034297	ENSORLP00000000370	Epidermal growth factor.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.675
egf	fgf8	ENSORLP00000034297	ENSORLP00000042553	Epidermal growth factor.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.677
egf	nrp1	ENSORLP00000034297	ENSORLP00000042087	Epidermal growth factor.	Neuropilin; Belongs to the neuropilin family.	0.563
egf	vegfc	ENSORLP00000034297	ENSORLP00000002709	Epidermal growth factor.	PDGF_2 domain-containing protein; Belongs to the PDGF/VEGF growth factor family.	0.556
fgf3	LOC101159747	ENSORLP00000000370	ENSORLP00000015020	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.422
fgf3	egf	ENSORLP00000000370	ENSORLP00000034297	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Epidermal growth factor.	0.675
fgf3	fgf8	ENSORLP00000000370	ENSORLP00000042553	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.829
fgf3	foxi2	ENSORLP00000000370	ENSORLP00000038059	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Forkhead box i1.	0.618
fgf3	nrp1	ENSORLP00000000370	ENSORLP00000042087	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Neuropilin; Belongs to the neuropilin family.	0.476
fgf8	LOC101159747	ENSORLP00000042553	ENSORLP00000015020	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.432
fgf8	egf	ENSORLP00000042553	ENSORLP00000034297	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Epidermal growth factor.	0.677
fgf8	fgf3	ENSORLP00000042553	ENSORLP00000000370	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.829
fgf8	foxi2	ENSORLP00000042553	ENSORLP00000038059	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Forkhead box i1.	0.481
fgf8	nrp1	ENSORLP00000042553	ENSORLP00000042087	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Neuropilin; Belongs to the neuropilin family.	0.480
fgf8	shh	ENSORLP00000042553	ENSORLP00000013115	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	Hedgehog protein; Intercellular signal essential for a variety of patterning events during development.	0.800
foxi2	fgf3	ENSORLP00000038059	ENSORLP00000000370	Forkhead box i1.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.618
foxi2	fgf8	ENSORLP00000038059	ENSORLP00000042553	Forkhead box i1.	Fibroblast growth factor; Belongs to the heparin-binding growth factors family.	0.481
nrp1	egf	ENSORLP00000042087	ENSORLP00000034297	Neuropilin; Belongs to the neuropilin family.	Epidermal growth factor.	0.563