STRINGSTRING
eif2b1 eif2b1 sumo1 sumo1 elac2 elac2 upf3b upf3b LOC101166133 LOC101166133 LOC101175126 LOC101175126 LOC101167527 LOC101167527 clns1a clns1a snupn snupn paip1 paip1 LOC101173816 LOC101173816 nxf1 nxf1 eif3f eif3f LOC101160693 LOC101160693 eif2s3 eif2s3 LOC101169122 LOC101169122 trnt1 trnt1 sumo2 sumo2 seh1l seh1l ran ran eif2s2 eif2s2 Pop7 Pop7 LOC101167445 LOC101167445 tgs1 tgs1 elac1 elac1 LOC101158762 LOC101158762 eif3g eif3g eif3j eif3j nmd3 nmd3 eif4ebp1 eif4ebp1 nup214 nup214 Gemin8 Gemin8 gemin7 gemin7 nup58 nup58 LOC101170959 LOC101170959 LOC101170939 LOC101170939 eef1a eef1a nup155 nup155 LOC101164818 LOC101164818 thoc5 thoc5 UPF1 UPF1 thoc2 thoc2 eif4a2 eif4a2 eif3b eif3b ddx20 ddx20 fmr1 fmr1 rpp38 rpp38 sumo2-2 sumo2-2 gemin4 gemin4 strap strap LOC100049345 LOC100049345 LOC101155548 LOC101155548 LOC101167578 LOC101167578 ncbp2 ncbp2 LOC101154983 LOC101154983 fxr1 fxr1 eif2b5 eif2b5 ALYREF ALYREF prmt5 prmt5 nup153 nup153 aaas aaas RPP14 RPP14 H2MDZ5_ORYLA H2MDZ5_ORYLA LOC101169703 LOC101169703 LOC101165680 LOC101165680 rangap1 rangap1 eif3i eif3i eif3a eif3a LOC101163268 LOC101163268 pop5 pop5 nup93 nup93 Tacc3 Tacc3 nup205 nup205 LOC101169438 LOC101169438 eif2b3 eif2b3 LOC101163319 LOC101163319 rbm8a rbm8a eif2b4 eif2b4 nup37 nup37 eif4b eif4b H2MR55_ORYLA H2MR55_ORYLA eif4g3 eif4g3 UPF2 UPF2 nup62 nup62 pabpc4 pabpc4 nup43 nup43 thoc1 thoc1 LOC101166761 LOC101166761 Pnn Pnn eif5 eif5 LOC101156233 LOC101156233 phax phax LOC100049338 LOC100049338 nup160 nup160 LOC101169085 LOC101169085 kpnb1 kpnb1 sec13 sec13 nup50 nup50 xpot xpot pop4 pop4 ndc1 ndc1 eif3e eif3e NCBP1 NCBP1 thoc7 thoc7 gemin6 gemin6 nxt2 nxt2 LOC100049330 LOC100049330 nup85 nup85 pabpc1 pabpc1 LOC101167611 LOC101167611 eif2b2 eif2b2 pym1 pym1 nup133 nup133 sap18 sap18 LOC101158109 LOC101158109 LOC101165490 LOC101165490 eif4ebp2 eif4ebp2 LOC101158558 LOC101158558 sumo4 sumo4 pop1 pop1 LOC101160447 LOC101160447 rnps1 rnps1 tardbp tardbp nup98 nup98 LOC101170539 LOC101170539 nup210 nup210 xpo5 xpo5 EIF4G1 EIF4G1 LOC101174301 LOC101174301 thoc3 thoc3 acin1 acin1 eif4e2 eif4e2 eif4ebp3 eif4ebp3 eif5b eif5b LOC101163413 LOC101163413 nup35 nup35 casc3 casc3 rae1 rae1 gemin5 gemin5 nup42 nup42 ube2i ube2i nup107 nup107
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
eif2b1Eukaryotic translation initiation factor 2B, subunit 1 alpha; Belongs to the eIF-2B alpha/beta/delta subunits family. (302 aa)
sumo1Small ubiquitin-related modifier. (101 aa)
elac2ElaC ribonuclease Z 2. (826 aa)
upf3bUPF3B regulator of nonsense mediated mRNA decay. (457 aa)
LOC101166133Eukaryotic translation initiation factor 3 subunit D; mRNA cap-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. In the eIF-3 complex, eif3d specifically recognizes and binds the 7- methylguanosine cap of a subset of mRNAs. (562 aa)
LOC101175126Exportin 1 (CRM1 homolog, yeast) a. (1066 aa)
LOC101167527Ribonuclease P 21 subunit. (146 aa)
clns1aChloride channel, nucleotide-sensitive, 1A. (245 aa)
snupnSnurportin 1. (382 aa)
paip1Poly(A) binding protein interacting protein 1. (451 aa)
LOC101173816Eukaryotic translation initiation factor 1A X-linked b; Seems to be required for maximal rate of protein biosynthesis. Enhances ribosome dissociation into subunits and stabilizes the binding of the initiator Met-tRNA(I) to 40 S ribosomal subunits. (144 aa)
nxf1Zgc:153681. (665 aa)
eif3fEukaryotic translation initiation factor 3 subunit F; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (274 aa)
LOC101160693Ran GTPase activating protein 1b. (564 aa)
eif2s3Eukaryotic translation initiation factor 2, subunit 3 gamma. (472 aa)
LOC101169122Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (631 aa)
trnt1tRNA nucleotidyl transferase, CCA-adding, 1; Belongs to the tRNA nucleotidyltransferase/poly(A) polymerase family. (423 aa)
sumo2Small ubiquitin-related modifier. (96 aa)
seh1lSEH1-like (S. cerevisiae); Belongs to the WD repeat SEC13 family. (341 aa)
ranGTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family. (219 aa)
eif2s2Eukaryotic translation initiation factor 2, subunit 2 beta. (331 aa)
Pop7Ribonuclease P protein subunit p20; Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends. Also a component of the MRP ribonuclease complex, which cleaves pre-rRNA sequences. (139 aa)
LOC101167445TAR DNA binding protein. (402 aa)
tgs1LYN proto-oncogene, Src family tyrosine kinase. (809 aa)
elac1ElaC ribonuclease Z 1. (414 aa)
LOC101158762Alba domain-containing protein. (187 aa)
eif3gEukaryotic translation initiation factor 3 subunit G; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. This subunit can bind 18S rRNA. (297 aa)
eif3jEukaryotic translation initiation factor 3 subunit J; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (261 aa)
nmd360S ribosomal export protein NMD3; Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit; Belongs to the NMD3 family. (504 aa)
eif4ebp1Uncharacterized protein. (137 aa)
nup214Nup214_FG domain-containing protein. (1974 aa)
Gemin8Gem (nuclear organelle) associated protein 8. (215 aa)
gemin7Gem (nuclear organelle) associated protein 7. (128 aa)
nup58Nucleoporin 58. (598 aa)
LOC101170959Apoptotic chromatin condensation inducer 1b. (1146 aa)
LOC101170939Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (462 aa)
eef1aElongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis; Belongs to the TRAFAC class translation factor GTPase superfamily. Classic translation factor GTPase family. EF-Tu/EF-1A subfamily. (461 aa)
nup155Nucleoporin 155. (1368 aa)
LOC101164818Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1252 aa)
thoc5THO complex 5. (684 aa)
UPF1UPF1 RNA helicase and ATPase. (1101 aa)
thoc2THO complex 2. (1560 aa)
eif4a2Eukaryotic translation initiation factor 4A, isoform 2; Belongs to the DEAD box helicase family. (411 aa)
eif3bEukaryotic translation initiation factor 3 subunit B; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome; Belongs to the eIF-3 subunit B family. (681 aa)
ddx20DEAD (Asp-Glu-Ala-Asp) box polypeptide 20; Belongs to the DEAD box helicase family. (748 aa)
fmr1Fragile X mental retardation 1. (598 aa)
rpp38Ribonuclease P/MRP 38 subunit. (275 aa)
sumo2-2Small ubiquitin-related modifier. (95 aa)
gemin4Gem (nuclear organelle) associated protein 4. (1112 aa)
strapSerine/threonine kinase receptor associated protein. (329 aa)
LOC100049345Survival of motor neuron 1, telomeric. (283 aa)
LOC101155548Eukaryotic translation initiation factor 4A1B; Belongs to the DEAD box helicase family. (405 aa)
LOC101167578UPF3A regulator of nonsense mediated mRNA decay. (466 aa)
ncbp2Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (164 aa)
LOC101154983Fragile X mental retardation, autosomal homolog 2. (674 aa)
fxr1Fragile X mental retardation, autosomal homolog 1. (679 aa)
eif2b5Eukaryotic translation initiation factor 2B, subunit 5 epsilon. (707 aa)
ALYREFAly/REF export factor. (268 aa)
prmt5Protein arginine N-methyltransferase 5; Arginine methyltransferase that can both catalyze the formation of omega-N monomethylarginine (MMA) and symmetrical dimethylarginine (sDMA); Belongs to the class I-like SAM-binding methyltransferase superfamily. (651 aa)
nup153Nucleoporin 153. (1515 aa)
aaasAchalasia, adrenocortical insufficiency, alacrimia. (514 aa)
RPP14Ribonuclease P/MRP subunit p14. (136 aa)
H2MDZ5_ORYLARibonuclease P and MRP subunit p25, b. (217 aa)
LOC101169703UBIQUITIN_CONJUGAT_2 domain-containing protein; Belongs to the ubiquitin-conjugating enzyme family. (158 aa)
LOC101165680SUMO specific peptidase 2. (606 aa)
rangap1RAN GTPase activating protein 1a. (554 aa)
eif3iEukaryotic translation initiation factor 3 subunit I; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (325 aa)
eif3aEukaryotic translation initiation factor 3 subunit A; RNA-binding component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (1260 aa)
LOC101163268POM121 transmembrane nucleoporin. (1162 aa)
pop5Ribonuclease P/MRP protein subunit POP5; Component of ribonuclease P, a protein complex that generates mature tRNA molecules by cleaving their 5'-ends. (166 aa)
nup93Nuclear pore complex protein Nup93; Plays a role in the nuclear pore complex (NPC) assembly and/or maintenance; Belongs to the nucleoporin interacting component (NIC) family. (820 aa)
Tacc3TACC_C domain-containing protein. (306 aa)
nup205Nucleoporin 205. (1992 aa)
LOC101169438Cytoplasmic FMR1-interacting protein; Belongs to the CYFIP family. (1253 aa)
eif2b3Eukaryotic translation initiation factor 2B, subunit 3 gamma. (454 aa)
LOC101163319DEAD/H (Asp-Glu-Ala-Asp/His) box polypeptide 19 (DBP5 homolog, yeast). (488 aa)
rbm8aRNA-binding protein 8A; Core component of the splicing-dependent multiprotein exon junction complex (EJC) deposited at splice junctions on mRNAs. (175 aa)
eif2b4Eukaryotic translation initiation factor 2B, subunit 4 delta; Belongs to the eIF-2B alpha/beta/delta subunits family. (532 aa)
nup37Nucleoporin 37. (323 aa)
eif4bEukaryotic translation initiation factor 4Bb. (637 aa)
H2MR55_ORYLARibonuclease P/MRP 25 subunit-like. (184 aa)
eif4g3Eukaryotic translation initiation factor 4 gamma, 3a. (1731 aa)
UPF2UPF2 regulator of nonsense mediated mRNA decay. (1275 aa)
nup62Nsp1_C domain-containing protein. (553 aa)
pabpc4Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (629 aa)
nup43Nucleoporin 43. (372 aa)
thoc1THO complex 1. (654 aa)
LOC101166761Eukaryotic translation initiation factor 4eb; Belongs to the eukaryotic initiation factor 4E family. (243 aa)
PnnPinin, desmosome associated protein. (511 aa)
eif5Eukaryotic translation initiation factor 5. (432 aa)
LOC101156233Eukaryotic translation initiation factor 4, gamma 2b. (933 aa)
phaxPhosphorylated adaptor for RNA export. (397 aa)
LOC100049338Elongation factor 1-alpha; This protein promotes the GTP-dependent binding of aminoacyl- tRNA to the A-site of ribosomes during protein biosynthesis. (456 aa)
nup160Nucleoporin 160. (1397 aa)
LOC101169085Eukaryotic translation initiation factor 4E family member 1c; Belongs to the eukaryotic initiation factor 4E family. (216 aa)
kpnb1Karyopherin (importin) beta 1. (876 aa)
sec13SEC13 homolog, nuclear pore and COPII coat complex component; Belongs to the WD repeat SEC13 family. (320 aa)
nup50Nucleoporin 50. (452 aa)
xpotExportin-T; tRNA nucleus export receptor which facilitates tRNA translocation across the nuclear pore complex. Belongs to the exportin family. (1041 aa)
pop4Ribonuclease P protein subunit p29; Component of ribonuclease P, a ribonucleoprotein complex that generates mature tRNA molecules by cleaving their 5'-ends. (221 aa)
ndc1NDC1 transmembrane nucleoporin. (668 aa)
eif3eEukaryotic translation initiation factor 3 subunit E; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (445 aa)
NCBP1Nuclear cap binding protein subunit 1. (799 aa)
thoc7THO complex 7. (239 aa)
gemin6Gem (nuclear organelle) associated protein 6. (168 aa)
nxt2Nuclear transport factor 2-like export factor 2. (143 aa)
LOC100049330Eukaryotic translation initiation factor 4ea; Belongs to the eukaryotic initiation factor 4E family. (265 aa)
nup85Nuclear pore complex protein Nup85; Functions as a component of the nuclear pore complex (NPC). (652 aa)
pabpc1Polyadenylate-binding protein; Binds the poly(A) tail of mRNA. Belongs to the polyadenylate-binding protein type-1 family. (635 aa)
LOC101167611Mago homolog, exon junction complex subunit. (147 aa)
eif2b2Eukaryotic translation initiation factor 2B, subunit 2 beta; Belongs to the eIF-2B alpha/beta/delta subunits family. (355 aa)
pym1PYM homolog 1, exon junction complex associated factor. (207 aa)
nup133Nucleoporin 133. (1138 aa)
sap18Histone deacetylase complex subunit SAP18; Involved in the tethering of the SIN3 complex to core histone proteins. (153 aa)
LOC101158109Zgc:193690. (521 aa)
LOC101165490Eukaryotic translation initiation factor 4E binding protein 1. (120 aa)
eif4ebp2Eukaryotic translation initiation factor 4E binding protein 2. (126 aa)
LOC101158558Uncharacterized protein. (1715 aa)
sumo4Small ubiquitin-related modifier. (101 aa)
pop1POP1 homolog, ribonuclease P/MRP subunit. (953 aa)
LOC101160447RAN binding protein 2. (3134 aa)
rnps1RNA binding protein S1, serine-rich domain. (273 aa)
tardbpTAR DNA binding protein, like. (299 aa)
nup98Nucleoporin 98. (1820 aa)
LOC101170539Exportin 1 (CRM1 homolog, yeast) b. (1084 aa)
nup210Nucleoporin 210. (1883 aa)
xpo5Exportin 5. (1218 aa)
EIF4G1Eukaryotic translation initiation factor 4 gamma 1. (1695 aa)
LOC101174301Eukaryotic translation initiation factor 3 subunit C; Component of the eukaryotic translation initiation factor 3 (eIF-3) complex, which is involved in protein synthesis of a specialized repertoire of mRNAs and, together with other initiation factors, stimulates binding of mRNA and methionyl-tRNAi to the 40S ribosome. The eIF-3 complex specifically targets and initiates translation of a subset of mRNAs involved in cell proliferation. (953 aa)
thoc3THO complex 3. (351 aa)
acin1SAP domain-containing protein. (1655 aa)
eif4e2Eukaryotic translation initiation factor 4E family member 2; Belongs to the eukaryotic initiation factor 4E family. (237 aa)
eif4ebp3Eukaryotic translation initiation factor 4E binding protein 3. (109 aa)
eif5bEukaryotic translation initiation factor 5B. (1195 aa)
LOC101163413Eukaryotic translation initiation factor 1B. (113 aa)
nup35Nucleoporin NUP53; Functions as a component of the nuclear pore complex (NPC). Belongs to the Nup35 family. (297 aa)
casc3Casc3 exon junction complex subunit. (721 aa)
rae1Ribonucleic acid export 1. (368 aa)
gemin5Gem (nuclear organelle) associated protein 5. (1411 aa)
nup42Nucleoporin 42. (423 aa)
ube2iUbiquitin-conjugating enzyme E2Ib; Belongs to the ubiquitin-conjugating enzyme family. (158 aa)
nup107Nuclear pore complex protein; Functions as a component of the nuclear pore complex (NPC). (916 aa)
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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