STRINGSTRING
cdipt cdipt INPP5A INPP5A inpp5e inpp5e ocrl ocrl ip6k2 ip6k2 calml4 calml4 dgke dgke pik3r1 pik3r1 plcd3 plcd3 LOC101167819 LOC101167819 PLCZ1 PLCZ1 LOC100049529 LOC100049529 pten pten LOC101160679 LOC101160679 calm3 calm3 mtmr6 mtmr6 LOC101163203 LOC101163203 PRKCB PRKCB LOC101159746 LOC101159746 PIK3CA PIK3CA LOC101168152 LOC101168152 PLCB4 PLCB4 LOC101167907 LOC101167907 PLCB1 PLCB1 LOC101161735 LOC101161735 mtmr14 mtmr14 LOC101170855 LOC101170855 LOC101155144 LOC101155144 pik3c2b pik3c2b LOC101157977 LOC101157977 inppl1 inppl1 MTMR4 MTMR4 Itpr2 Itpr2 pi4k2a pi4k2a LOC101166093 LOC101166093 pip4p2 pip4p2 impad1 impad1 PRKCA PRKCA inpp5f inpp5f inpp5b inpp5b LOC101167700 LOC101167700 plcd4 plcd4 LOC101173218 LOC101173218 LOC101154951 LOC101154951 itpka itpka LOC101157624 LOC101157624 plcg2 plcg2 inpp5d inpp5d LOC101169535 LOC101169535 LOC101161564 LOC101161564 itpkb itpkb H2MSU3_ORYLA H2MSU3_ORYLA LOC101173208 LOC101173208 DGKQ DGKQ pikfyve pikfyve mtm1 mtm1 LOC101175056 LOC101175056 PTEN PTEN pi4kb pi4kb LOC101163728 LOC101163728 LOC101161567 LOC101161567 ppip5k1 ppip5k1 pik3c2g pik3c2g ENSORLP00000027534 ENSORLP00000027534 LOC101163663 LOC101163663 itpk1 itpk1 inpp4b inpp4b dgkz dgkz ippk ippk LOC101161464 LOC101161464 plcg1 plcg1 inpp1 inpp1 LOC101169066 LOC101169066 PIP4K2B PIP4K2B LOC101172720 LOC101172720 LOC101175365 LOC101175365 pik3r3 pik3r3 pik3cb pik3cb pik3c3 pik3c3 LOC101159467 LOC101159467 LOC101163245 LOC101163245 LOC105354871 LOC105354871 LOC101173168 LOC101173168 plcb2 plcb2 LOC101161334 LOC101161334 pip5k1c pip5k1c LOC101157342 LOC101157342 LOC101164921 LOC101164921 plce1 plce1 ENSORLP00000039425 ENSORLP00000039425 LOC101172964 LOC101172964 mtmr2 mtmr2 ipmk ipmk LOC101163204 LOC101163204 LOC101166403 LOC101166403 mtmr3 mtmr3 LOC105355004 LOC105355004 LOC101165301 LOC101165301 LOC101168299 LOC101168299 pik3c2a pik3c2a LOC101166344 LOC101166344 pik3cd pik3cd LOC101165102 LOC101165102 synj1 synj1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
cdiptCDP-diacylglycerol--inositol 3-phosphatidyltransferase. (204 aa)
INPP5AInositol polyphosphate-5-phosphatase A. (413 aa)
inpp5eInositol polyphosphate-5-phosphatase E. (616 aa)
ocrlOCRL inositol polyphosphate-5-phosphatase. (971 aa)
ip6k2Kinase; Belongs to the inositol phosphokinase (IPK) family. (437 aa)
calml4Calmodulin-like 4a. (153 aa)
dgkeDiacylglycerol kinase. (576 aa)
pik3r1Phosphoinositide-3-kinase, regulatory subunit 1 (alpha). (728 aa)
plcd3Phosphoinositide phospholipase C. (790 aa)
LOC101167819SAC1 like phosphatidylinositide phosphatase b. (586 aa)
PLCZ1Phosphoinositide phospholipase C. (659 aa)
LOC1000495291-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1237 aa)
ptenPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (437 aa)
LOC101160679Kinase; Belongs to the inositol phosphokinase (IPK) family. (683 aa)
calm3Calmodulin-A; Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases. (149 aa)
mtmr6Myotubularin related protein 6. (654 aa)
LOC101163203Inositol-1-monophosphatase. (328 aa)
PRKCBProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (680 aa)
LOC101159746Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (670 aa)
PIK3CAPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
LOC101168152Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1234 aa)
LOC101167907Phosphoinositide phospholipase C. (771 aa)
PLCB11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1242 aa)
LOC101161735Myotubularin related protein 7a. (643 aa)
mtmr14Myotubularin related protein 14. (499 aa)
LOC101170855SAC1 like phosphatidylinositide phosphatase a. (586 aa)
LOC101155144Uncharacterized protein. (466 aa)
pik3c2bPhosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 beta; Belongs to the PI3/PI4-kinase family. (1603 aa)
LOC101157977Myotubularin related protein 1a. (670 aa)
inppl1Inositol polyphosphate phosphatase-like 1a. (1249 aa)
MTMR4Myotubularin related protein 4. (1187 aa)
Itpr2Inositol 1,4,5-trisphosphate receptor, type 2. (1587 aa)
pi4k2aPhosphatidylinositol 4-kinase type 2 alpha. (496 aa)
LOC101166093Inositol-1-monophosphatase. (283 aa)
pip4p2Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (301 aa)
impad1Inositol monophosphatase domain containing 1. (343 aa)
PRKCAProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (709 aa)
inpp5fInositol polyphosphate-5-phosphatase F. (1130 aa)
inpp5bInositol polyphosphate-5-phosphatase B. (899 aa)
LOC101167700Inositol 1,4,5-trisphosphate receptor, type 1a. (2664 aa)
plcd4Phosphoinositide phospholipase C. (733 aa)
LOC101173218Phosphatidylinositol-5-phosphate 4-kinase, type II, gamma b. (408 aa)
LOC101154951Diacylglycerol kinase. (729 aa)
itpkaKinase; Belongs to the inositol phosphokinase (IPK) family. (436 aa)
LOC101157624Phosphatidate cytidylyltransferase; Provides CDP-diacylglycerol, an important precursor for the synthesis of phosphatidylinositol, phosphatidylglycerol, and cardiolipin. (453 aa)
plcg21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1247 aa)
inpp5dInositol polyphosphate-5-phosphatase D. (1092 aa)
LOC101169535Phosphatidylinositol-5-phosphate 4-kinase, type II, gamma a. (416 aa)
LOC101161564Phosphatidate cytidylyltransferase; Provides CDP-diacylglycerol, an important precursor for the synthesis of phosphatidylinositol, phosphatidylglycerol, and cardiolipin. (451 aa)
itpkbKinase; Belongs to the inositol phosphokinase (IPK) family. (711 aa)
H2MSU3_ORYLAUncharacterized protein. (420 aa)
LOC101173208Phosphoinositide phospholipase C. (770 aa)
DGKQDiacylglycerol kinase. (908 aa)
pikfyvePhosphoinositide kinase, FYVE finger containing. (2070 aa)
mtm1Myotubularin 1. (602 aa)
LOC101175056Phosphoinositide phospholipase C. (749 aa)
PTENPhosphatase and tensin homolog; Tumor suppressor. Acts as a dual-specificity protein phosphatase, dephosphorylating tyrosine-, serine- and threonine- phosphorylated proteins. Also acts as a lipid phosphatase. Belongs to the PTEN phosphatase protein family. (415 aa)
pi4kbUncharacterized protein; Belongs to the PI3/PI4-kinase family. (811 aa)
LOC101163728Uncharacterized protein. (409 aa)
LOC101161567Phosphatidylinositol 4-kinase beta; Belongs to the PI3/PI4-kinase family. (967 aa)
ppip5k1Inositol hexakisphosphate and diphosphoinositol-pentakisphosphate kinase; Bifunctional inositol kinase that acts in concert with the IP6K kinases IP6K1, IP6K2 and IP6K3 to synthesize the diphosphate group-containing inositol pyrophosphates diphosphoinositol pentakisphosphate, PP-InsP5, and bis-diphosphoinositol tetrakisphosphate, (PP)2-InsP4. PP-InsP5 and (PP)2-InsP4, also respectively called InsP7 and InsP8, regulate a variety of cellular processes, including apoptosis, vesicle trafficking, cytoskeletal dynamics, exocytosis, insulin signaling and neutrophil activation. Phosphorylates [...] (1477 aa)
pik3c2gPhosphatidylinositol-4-phosphate 3-kinase catalytic subunit type 2 gamma; Belongs to the PI3/PI4-kinase family. (1357 aa)
ENSORLP00000027534Uncharacterized protein. (189 aa)
LOC101163663Phosphatidylinositol-4-phosphate 5-kinase, type I, beta b. (543 aa)
itpk1Inositol-tetrakisphosphate 1-kinase; Kinase that can phosphorylate various inositol polyphosphate such as Ins(3,4,5,6)P4 or Ins(1,3,4)P3. Belongs to the ITPK1 family. (409 aa)
inpp4bInositol polyphosphate-4-phosphatase type II B. (941 aa)
dgkzDiacylglycerol kinase. (1021 aa)
ippkInositol-pentakisphosphate 2-kinase; Phosphorylates Ins(1,3,4,5,6)P5 at position 2 to form Ins(1,2,3,4,5,6)P6 (InsP6 or phytate). (495 aa)
LOC101161464Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (666 aa)
plcg11-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1311 aa)
inpp1Si:ch211-160o17.2. (379 aa)
LOC101169066Phosphatidylinositol-4-phosphate 5-kinase, type I, gamma b. (785 aa)
PIP4K2BPhosphatidylinositol-5-phosphate 4-kinase type 2 beta. (412 aa)
LOC101172720Phosphoinositide phospholipase C. (770 aa)
LOC1011753651-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1161 aa)
pik3r3Phosphoinositide-3-kinase, regulatory subunit 3b (gamma). (719 aa)
pik3cbPhosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1078 aa)
pik3c3Phosphatidylinositol 3-kinase catalytic subunit type 3. (884 aa)
LOC101159467Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (263 aa)
LOC101163245Kinase; Belongs to the inositol phosphokinase (IPK) family. (472 aa)
LOC105354871Kinase; Belongs to the inositol phosphokinase (IPK) family. (583 aa)
LOC101173168Phosphatidylinositol-4-phosphate 5-kinase, type I, alpha, b. (610 aa)
plcb21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1248 aa)
LOC101161334Phosphatidylinositol-4,5-bisphosphate 4-phosphatase; Catalyzes the hydrolysis of phosphatidylinositol-4,5- bisphosphate (PtdIns-4,5-P2) to phosphatidylinositol-4-phosphate (PtdIns-4-P). (296 aa)
pip5k1cPhosphatidylinositol-4-phosphate 5-kinase, type I, gamma a. (722 aa)
LOC101157342Myotubularin related protein 7b. (572 aa)
LOC101164921Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (704 aa)
plce1Phospholipase C, epsilon 1. (2269 aa)
ENSORLP00000039425PI3K/PI4K domain-containing protein; Belongs to the PI3/PI4-kinase family. (93 aa)
LOC101172964Phosphoinositide phospholipase C. (765 aa)
mtmr2Myotubularin related protein 2. (640 aa)
ipmkKinase; Belongs to the inositol phosphokinase (IPK) family. (452 aa)
LOC101163204Phosphoinositide phospholipase C. (770 aa)
LOC101166403Phosphatidylinositol-4-phosphate 5-kinase, type I, beta a. (505 aa)
mtmr3Myotubularin related protein 3. (1230 aa)
LOC105355004Phosphatidylinositol-4-phosphate 5-kinase, type I, alpha, a. (573 aa)
LOC101165301Diacylglycerol kinase. (721 aa)
LOC101168299Inositol polyphosphate phosphatase-like 1b. (1220 aa)
pik3c2aPhosphatidylinositol-4-phosphate 3-kinase, catalytic subunit type 2 alpha; Belongs to the PI3/PI4-kinase family. (1725 aa)
LOC101166344Inositol-1-monophosphatase. (279 aa)
pik3cdPhosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1039 aa)
LOC101165102Diacylglycerol kinase. (1091 aa)
synj1Synaptojanin 1. (1731 aa)
Your Current Organism:
Oryzias latipes
NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka
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