110 items (Oryzias latipes) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC101154761	Signal transducer and activator of transcription. (763 aa)
	LOC101172160	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (594 aa)
	LOC101163430	Interferon regulatory factor. (293 aa)
	LOC101174244	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
	calml4	Calmodulin-like 4a. (153 aa)
	ikbkg	Inhibitor of nuclear factor kappa B kinase regulatory subunit gamma. (585 aa)
	IL12B	Interleukin-12 subunit beta; Belongs to the type I cytokine receptor family. Type 3 subfamily. (320 aa)
	ppp3r1	Uncharacterized protein. (170 aa)
	ikbkb	Inhibitor of nuclear factor kappa B kinase subunit beta. (801 aa)
	pik3r1	Phosphoinositide-3-kinase, regulatory subunit 1 (alpha). (728 aa)
	nfkb2	Nuclear factor of kappa light polypeptide gene enhancer in B-cells 2 (p49/p100). (956 aa)
	LOC101174595	Mitogen-activated protein kinase kinase kinase 14a. (866 aa)
	LOC101157952	Mitogen-activated protein kinase. (420 aa)
	LOC101174851	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
	LOC101162612	Serine/threonine-protein phosphatase. (549 aa)
	LOC101174762	Uncharacterized protein; Belongs to the peptidase C14A family. (388 aa)
	SRC	Tyrosine-protein kinase. (544 aa)
	calm3	Calmodulin-A; Calmodulin mediates the control of a large number of enzymes, ion channels and other proteins by Ca(2+). Among the enzymes to be stimulated by the calmodulin-Ca(2+) complex are a number of protein kinases and phosphatases. (149 aa)
	LOC101161493	Nuclear factor of activated T cells 1. (858 aa)
	LOC101155194	Uncharacterized protein. (193 aa)
	PIK3CA	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
	LOC101168152	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
	LOC101175696	Mitogen-activated protein kinase. (354 aa)
	LOC101154993	Mitogen-activated protein kinase. (368 aa)
	LOC101171857	Component of inhibitor of nuclear factor kappa B kinase complex. (732 aa)
	ptgs2	EGF-like domain-containing protein. (607 aa)
	jun	BZIP domain-containing protein; Belongs to the bZIP family. (306 aa)
	LOC101172593	Tumor necrosis factor a (TNF superfamily, member 2). (279 aa)
	LOC101155144	Uncharacterized protein. (466 aa)
	egr3	Uncharacterized protein. (410 aa)
	LOC101158728	V-rel avian reticuloendotheliosis viral oncogene homolog A. (617 aa)
	LOC100125536	Uncharacterized protein; Belongs to the peptidase C14A family. (389 aa)
	casp8	Uncharacterized protein; Belongs to the peptidase C14A family. (481 aa)
	Itpr2	Inositol 1,4,5-trisphosphate receptor, type 2. (1587 aa)
	hras	HRas proto-oncogene, GTPase a. (189 aa)
	raf1	Raf-1 proto-oncogene, serine/threonine kinase a. (677 aa)
	nfatc3	Nuclear factor of activated T cells 3a. (1091 aa)
	LOC101159747	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (389 aa)
	CHUK	Component of inhibitor of nuclear factor kappa B kinase complex. (765 aa)
	il17d	Uncharacterized protein. (210 aa)
	irf9	IRF tryptophan pentad repeat domain-containing protein. (435 aa)
	cyld	Cylindromatosis (turban tumor syndrome), a; Belongs to the peptidase C19 family. (918 aa)
	LOC101163809	Cylindromatosis (turban tumor syndrome), b. (707 aa)
	LOC101166422	ADP-ribosylation factor 2b. (976 aa)
	H2MGG8_ORYLA	C-type lectin domain-containing protein. (192 aa)
	LOC101155451	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (482 aa)
	LOC101167700	Inositol 1,4,5-trisphosphate receptor, type 1a. (2664 aa)
	egr2	Early growth response 2b. (449 aa)
	plcg2	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1247 aa)
	il10	Interleukin 10. (181 aa)
	MAPKAPK2	MAPK activated protein kinase 2a; Belongs to the protein kinase superfamily. (389 aa)
	ikbke	Inhibitor of nuclear factor kappa B kinase subunit epsilon. (718 aa)
	LOC101162015	Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a. (303 aa)
	LOC101172250	Serine/threonine-protein phosphatase. (511 aa)
	LOC101171005	Nuclear factor of activated T cells 2a. (893 aa)
	plk3	Serine/threonine-protein kinase PLK. (666 aa)
	LOC101159668	Mitogen-activated protein kinase. (361 aa)
	akt1	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (496 aa)
	LOC101161792	SCY domain-containing protein. (126 aa)
	H2MSU3_ORYLA	Uncharacterized protein. (420 aa)
	nfkbia	Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha b. (316 aa)
	mras	Muscle RAS oncogene homolog. (209 aa)
	LOC101160956	JunE proto-oncogene, AP-1 transcription factor subunit. (425 aa)
	LOC101173444	Uncharacterized protein. (193 aa)
	nfatc1	RHD domain-containing protein. (898 aa)
	LOC101163728	Uncharacterized protein. (409 aa)
	LOC101156706	Serine/threonine-protein phosphatase. (514 aa)
	LOC101164997	Mitogen-activated protein kinase. (384 aa)
	LOC101158722	BCL3 transcription coactivator. (477 aa)
	LOC101160731	Mitogen-activated protein kinase. (360 aa)
	pak1	Non-specific serine/threonine protein kinase. (571 aa)
	LOC101168674	Uncharacterized protein. (179 aa)
	cblb	Cbl proto-oncogene B, E3 ubiquitin protein ligase. (906 aa)
	LOC101161579	Uncharacterized protein. (199 aa)
	LOC101158607	Uncharacterized protein. (193 aa)
	LOC101165879	RHD domain-containing protein. (888 aa)
	LOC101168799	Mitogen-activated protein kinase. (488 aa)
	LOC101170619	Uncharacterized protein. (184 aa)
	LOC101154954	Zgc:55558. (189 aa)
	ENSORLP00000030118	CARD domain-containing protein. (96 aa)
	nfkb1	Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1. (922 aa)
	kras	GTPase KRas; Ras proteins bind GDP/GTP and possess intrinsic GTPase activity (By similarity). Plays an important role in the regulation of cell proliferation. (189 aa)
	prkcd	Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (709 aa)
	LOC101174431	RAS related. (196 aa)
	ENSORLP00000032968	Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (287 aa)
	LOC101164744	Uncharacterized protein. (395 aa)
	pik3r3	Phosphoinositide-3-kinase, regulatory subunit 3b (gamma). (719 aa)
	pik3cb	Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1078 aa)
	mdm2	MDM2 proto-oncogene. (498 aa)
	LOC101162468	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily. (479 aa)
	rras2	RAS related 2. (202 aa)
	LOC101162042	Mitogen-activated protein kinase. (361 aa)
	card9	Caspase recruitment domain family, member 9. (510 aa)
	LOC101164480	Tyrosine-protein kinase. (551 aa)
	syk	Tyrosine-protein kinase. (624 aa)
	LOC101168449	Cylindromatosis (turban tumor syndrome), like; Belongs to the peptidase C19 family. (769 aa)
	LOC101172896	RHD domain-containing protein. (790 aa)
	LOC101173855	Signal transducer and activator of transcription. (799 aa)
	LOC101167576	Uncharacterized protein. (943 aa)
	LOC101164960	C-type lectin domain-containing protein. (163 aa)
	ptpn11	Tyrosine-protein phosphatase non-receptor type; Belongs to the protein-tyrosine phosphatase family. Non- receptor class 2 subfamily. (596 aa)
	LOC101162905	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (369 aa)
	LOC101167618	Uncharacterized protein. (193 aa)
	bcl10	BCL10 immune signaling adaptor. (248 aa)
	arhgef12	Rho guanine nucleotide exchange factor (GEF) 12a. (1434 aa)
	LOC101168142	Serine/threonine-protein phosphatase. (522 aa)
	pik3cd	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1039 aa)
	LOC101158490	Signal transducer and activator of transcription. (746 aa)
	ksr1	Kinase suppressor of ras 1a. (978 aa)
	LOC101171170	MALT paracaspase 1. (811 aa)

Your Current Organism:

Oryzias latipes

NCBI taxonomy Id: 8090
Other names: Japanese medaka, Japanese rice fish, O. latipes, Poecilia latipes, medaka

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CHUK	LOC101154761	ENSORLP00000016017	ENSORLP00000000200	Component of inhibitor of nuclear factor kappa B kinase complex.	Signal transducer and activator of transcription.	0.478
CHUK	LOC101155451	ENSORLP00000016017	ENSORLP00000017781	Component of inhibitor of nuclear factor kappa B kinase complex.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.955
CHUK	LOC101158490	ENSORLP00000016017	ENSORLP00000044383	Component of inhibitor of nuclear factor kappa B kinase complex.	Signal transducer and activator of transcription.	0.435
CHUK	LOC101158722	ENSORLP00000016017	ENSORLP00000026687	Component of inhibitor of nuclear factor kappa B kinase complex.	BCL3 transcription coactivator.	0.628
CHUK	LOC101158728	ENSORLP00000016017	ENSORLP00000013930	Component of inhibitor of nuclear factor kappa B kinase complex.	V-rel avian reticuloendotheliosis viral oncogene homolog A.	0.666
CHUK	LOC101162015	ENSORLP00000016017	ENSORLP00000019864	Component of inhibitor of nuclear factor kappa B kinase complex.	Nuclear factor of kappa light polypeptide gene enhancer in B-cells inhibitor, alpha a.	0.961
CHUK	LOC101162468	ENSORLP00000016017	ENSORLP00000035304	Component of inhibitor of nuclear factor kappa B kinase complex.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.955
CHUK	LOC101163809	ENSORLP00000016017	ENSORLP00000017400	Component of inhibitor of nuclear factor kappa B kinase complex.	Cylindromatosis (turban tumor syndrome), b.	0.562
CHUK	LOC101166422	ENSORLP00000016017	ENSORLP00000017703	Component of inhibitor of nuclear factor kappa B kinase complex.	ADP-ribosylation factor 2b.	0.974
CHUK	LOC101167576	ENSORLP00000016017	ENSORLP00000038710	Component of inhibitor of nuclear factor kappa B kinase complex.	Uncharacterized protein.	0.562
CHUK	LOC101168449	ENSORLP00000016017	ENSORLP00000036637	Component of inhibitor of nuclear factor kappa B kinase complex.	Cylindromatosis (turban tumor syndrome), like; Belongs to the peptidase C19 family.	0.562
CHUK	LOC101171170	ENSORLP00000016017	ENSORLP00000045160	Component of inhibitor of nuclear factor kappa B kinase complex.	MALT paracaspase 1.	0.944
CHUK	LOC101171857	ENSORLP00000016017	ENSORLP00000011761	Component of inhibitor of nuclear factor kappa B kinase complex.	Component of inhibitor of nuclear factor kappa B kinase complex.	0.942
CHUK	LOC101172593	ENSORLP00000016017	ENSORLP00000013121	Component of inhibitor of nuclear factor kappa B kinase complex.	Tumor necrosis factor a (TNF superfamily, member 2).	0.836
CHUK	LOC101173855	ENSORLP00000016017	ENSORLP00000037640	Component of inhibitor of nuclear factor kappa B kinase complex.	Signal transducer and activator of transcription.	0.440
CHUK	LOC101174244	ENSORLP00000016017	ENSORLP00000001785	Component of inhibitor of nuclear factor kappa B kinase complex.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.955
CHUK	LOC101174595	ENSORLP00000016017	ENSORLP00000005737	Component of inhibitor of nuclear factor kappa B kinase complex.	Mitogen-activated protein kinase kinase kinase 14a.	0.974
CHUK	LOC101174851	ENSORLP00000016017	ENSORLP00000006529	Component of inhibitor of nuclear factor kappa B kinase complex.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.955
CHUK	akt1	ENSORLP00000016017	ENSORLP00000021301	Component of inhibitor of nuclear factor kappa B kinase complex.	Non-specific serine/threonine protein kinase; Belongs to the protein kinase superfamily.	0.955
CHUK	bcl10	ENSORLP00000016017	ENSORLP00000040686	Component of inhibitor of nuclear factor kappa B kinase complex.	BCL10 immune signaling adaptor.	0.900