(10 nodes) U4 snRNP, and U1 snRNA binding network (Acanthochromis polyacanthus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC110962189	Small nuclear ribonucleoprotein 70 (U1). (159 aa)
	LOC110946918	Small nuclear ribonucleoprotein G. (77 aa)
	ENSAPOP00000011318	LRRcap domain-containing protein. (170 aa)
	snrpa	Small nuclear ribonucleoprotein polypeptide A. (282 aa)
	snrpb	Small nuclear ribonucleoprotein polypeptides B and B1. (427 aa)
	snrpe	Small nuclear ribonucleoprotein E; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. Belongs to the snRNP Sm proteins family. (92 aa)
	ENSAPOP00000022281	Small nuclear ribonucleoprotein polypeptide F. (128 aa)
	snrpd2	Small nuclear ribonucleoprotein Sm D2. (118 aa)
	snrpc	U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. Belongs to the U1 [...] (148 aa)
	snrpd1	Small nuclear ribonucleoprotein Sm D1; Essential for pre-mRNA splicing. Implicated in the formation of stable, biologically active snRNP structures. Belongs to the snRNP core protein family. (183 aa)

Your Current Organism:

Acanthochromis polyacanthus

NCBI taxonomy Id: 80966
Other names: A. polyacanthus, Acanthochromis polyacathus, spiny chromis, spiny damselfish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSAPOP00000011318	ENSAPOP00000022281	ENSAPOP00000011318	ENSAPOP00000022281	LRRcap domain-containing protein.	Small nuclear ribonucleoprotein polypeptide F.	0.978
ENSAPOP00000011318	LOC110946918	ENSAPOP00000011318	ENSAPOP00000010747	LRRcap domain-containing protein.	Small nuclear ribonucleoprotein G.	0.963
ENSAPOP00000011318	LOC110962189	ENSAPOP00000011318	ENSAPOP00000007341	LRRcap domain-containing protein.	Small nuclear ribonucleoprotein 70 (U1).	0.939
ENSAPOP00000011318	snrpa	ENSAPOP00000011318	ENSAPOP00000013731	LRRcap domain-containing protein.	Small nuclear ribonucleoprotein polypeptide A.	0.925
ENSAPOP00000011318	snrpb	ENSAPOP00000011318	ENSAPOP00000016502	LRRcap domain-containing protein.	Small nuclear ribonucleoprotein polypeptides B and B1.	0.956
ENSAPOP00000011318	snrpc	ENSAPOP00000011318	ENSAPOP00000028608	LRRcap domain-containing protein.	U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. Belongs to the U1 [...]	0.948
ENSAPOP00000011318	snrpd1	ENSAPOP00000011318	ENSAPOP00000031903	LRRcap domain-containing protein.	Small nuclear ribonucleoprotein Sm D1; Essential for pre-mRNA splicing. Implicated in the formation of stable, biologically active snRNP structures. Belongs to the snRNP core protein family.	0.980
ENSAPOP00000011318	snrpd2	ENSAPOP00000011318	ENSAPOP00000027637	LRRcap domain-containing protein.	Small nuclear ribonucleoprotein Sm D2.	0.980
ENSAPOP00000011318	snrpe	ENSAPOP00000011318	ENSAPOP00000020517	LRRcap domain-containing protein.	Small nuclear ribonucleoprotein E; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. Belongs to the snRNP Sm proteins family.	0.983
ENSAPOP00000022281	ENSAPOP00000011318	ENSAPOP00000022281	ENSAPOP00000011318	Small nuclear ribonucleoprotein polypeptide F.	LRRcap domain-containing protein.	0.978
ENSAPOP00000022281	LOC110946918	ENSAPOP00000022281	ENSAPOP00000010747	Small nuclear ribonucleoprotein polypeptide F.	Small nuclear ribonucleoprotein G.	0.999
ENSAPOP00000022281	LOC110962189	ENSAPOP00000022281	ENSAPOP00000007341	Small nuclear ribonucleoprotein polypeptide F.	Small nuclear ribonucleoprotein 70 (U1).	0.996
ENSAPOP00000022281	snrpa	ENSAPOP00000022281	ENSAPOP00000013731	Small nuclear ribonucleoprotein polypeptide F.	Small nuclear ribonucleoprotein polypeptide A.	0.973
ENSAPOP00000022281	snrpb	ENSAPOP00000022281	ENSAPOP00000016502	Small nuclear ribonucleoprotein polypeptide F.	Small nuclear ribonucleoprotein polypeptides B and B1.	0.997
ENSAPOP00000022281	snrpc	ENSAPOP00000022281	ENSAPOP00000028608	Small nuclear ribonucleoprotein polypeptide F.	U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. Belongs to the U1 [...]	0.997
ENSAPOP00000022281	snrpd1	ENSAPOP00000022281	ENSAPOP00000031903	Small nuclear ribonucleoprotein polypeptide F.	Small nuclear ribonucleoprotein Sm D1; Essential for pre-mRNA splicing. Implicated in the formation of stable, biologically active snRNP structures. Belongs to the snRNP core protein family.	0.999
ENSAPOP00000022281	snrpd2	ENSAPOP00000022281	ENSAPOP00000027637	Small nuclear ribonucleoprotein polypeptide F.	Small nuclear ribonucleoprotein Sm D2.	0.999
ENSAPOP00000022281	snrpe	ENSAPOP00000022281	ENSAPOP00000020517	Small nuclear ribonucleoprotein polypeptide F.	Small nuclear ribonucleoprotein E; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. Belongs to the snRNP Sm proteins family.	0.999
LOC110946918	ENSAPOP00000011318	ENSAPOP00000010747	ENSAPOP00000011318	Small nuclear ribonucleoprotein G.	LRRcap domain-containing protein.	0.963
LOC110946918	ENSAPOP00000022281	ENSAPOP00000010747	ENSAPOP00000022281	Small nuclear ribonucleoprotein G.	Small nuclear ribonucleoprotein polypeptide F.	0.999