(20 nodes) Intrinsic apoptotic signaling pathway in response to endoplasmic reticulum stress network (Acanthochromis polyacanthus)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

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Others

textmining

co-expression

protein homology

Your Input:
	tmem117	Transmembrane protein 117. (520 aa)
	ENSAPOP00000031459	Protein kinase domain-containing protein. (248 aa)
	LOC110954579	BCL2 associated athanogene 6. (1218 aa)
	LOC110946580	CCAAT enhancer binding protein beta. (291 aa)
	LOC110957615	Endoplasmic reticulum to nucleus signaling 2. (978 aa)
	LOC110962959	Zgc:153993. (205 aa)
	aifm1	Apoptosis inducing factor mitochondrion associated 1. (656 aa)
	pdx1	Pancreatic and duodenal homeobox 1. (273 aa)
	bax	BCL2 associated X, apoptosis regulator a. (192 aa)
	LOC110972434	Uncharacterized protein. (715 aa)
	bcl2	BCL2 apoptosis regulator b. (228 aa)
	LOC110956031	Im:7152348. (148 aa)
	LOC110952586	Uncharacterized protein. (905 aa)
	LOC110964369	Tribbles pseudokinase 3. (351 aa)
	LOC110945652	Cyclic AMP-dependent transcription factor ATF-4-like. (438 aa)
	LOC110965865	BH4_2 domain-containing protein. (198 aa)
	ern1	Endoplasmic reticulum to nucleus signaling 1. (1079 aa)
	LOC110965885	Activating transcription factor 4a. (438 aa)
	ddit3	DNA-damage-inducible transcript 3. (313 aa)
	LOC110960138	Ubiquitin-like domain-containing protein. (1179 aa)

Your Current Organism:

Acanthochromis polyacanthus

NCBI taxonomy Id: 80966
Other names: A. polyacanthus, Acanthochromis polyacathus, spiny chromis, spiny damselfish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSAPOP00000031459	LOC110964369	ENSAPOP00000031459	ENSAPOP00000014861	Protein kinase domain-containing protein.	Tribbles pseudokinase 3.	0.483
LOC110945652	LOC110946580	ENSAPOP00000014214	ENSAPOP00000022503	Cyclic AMP-dependent transcription factor ATF-4-like.	CCAAT enhancer binding protein beta.	0.970
LOC110945652	LOC110964369	ENSAPOP00000014214	ENSAPOP00000014861	Cyclic AMP-dependent transcription factor ATF-4-like.	Tribbles pseudokinase 3.	0.847
LOC110945652	ddit3	ENSAPOP00000014214	ENSAPOP00000032326	Cyclic AMP-dependent transcription factor ATF-4-like.	DNA-damage-inducible transcript 3.	0.945
LOC110946580	LOC110945652	ENSAPOP00000022503	ENSAPOP00000014214	CCAAT enhancer binding protein beta.	Cyclic AMP-dependent transcription factor ATF-4-like.	0.970
LOC110946580	LOC110962959	ENSAPOP00000022503	ENSAPOP00000021381	CCAAT enhancer binding protein beta.	Zgc:153993.	0.433
LOC110946580	LOC110964369	ENSAPOP00000022503	ENSAPOP00000014861	CCAAT enhancer binding protein beta.	Tribbles pseudokinase 3.	0.675
LOC110946580	LOC110965865	ENSAPOP00000022503	ENSAPOP00000004482	CCAAT enhancer binding protein beta.	BH4_2 domain-containing protein.	0.476
LOC110946580	LOC110965885	ENSAPOP00000022503	ENSAPOP00000002867	CCAAT enhancer binding protein beta.	Activating transcription factor 4a.	0.970
LOC110946580	bax	ENSAPOP00000022503	ENSAPOP00000020432	CCAAT enhancer binding protein beta.	BCL2 associated X, apoptosis regulator a.	0.429
LOC110946580	bcl2	ENSAPOP00000022503	ENSAPOP00000018951	CCAAT enhancer binding protein beta.	BCL2 apoptosis regulator b.	0.476
LOC110946580	ddit3	ENSAPOP00000022503	ENSAPOP00000032326	CCAAT enhancer binding protein beta.	DNA-damage-inducible transcript 3.	0.917
LOC110952586	LOC110964369	ENSAPOP00000015669	ENSAPOP00000014861	Uncharacterized protein.	Tribbles pseudokinase 3.	0.483
LOC110954579	aifm1	ENSAPOP00000025449	ENSAPOP00000021290	BCL2 associated athanogene 6.	Apoptosis inducing factor mitochondrion associated 1.	0.423
LOC110957615	LOC110964369	ENSAPOP00000021639	ENSAPOP00000014861	Endoplasmic reticulum to nucleus signaling 2.	Tribbles pseudokinase 3.	0.483
LOC110957615	ern1	ENSAPOP00000021639	ENSAPOP00000007890	Endoplasmic reticulum to nucleus signaling 2.	Endoplasmic reticulum to nucleus signaling 1.	0.895
LOC110960138	aifm1	ENSAPOP00000032061	ENSAPOP00000021290	Ubiquitin-like domain-containing protein.	Apoptosis inducing factor mitochondrion associated 1.	0.423
LOC110962959	LOC110946580	ENSAPOP00000021381	ENSAPOP00000022503	Zgc:153993.	CCAAT enhancer binding protein beta.	0.433
LOC110962959	LOC110965865	ENSAPOP00000021381	ENSAPOP00000004482	Zgc:153993.	BH4_2 domain-containing protein.	0.980
LOC110962959	aifm1	ENSAPOP00000021381	ENSAPOP00000021290	Zgc:153993.	Apoptosis inducing factor mitochondrion associated 1.	0.931