(47 nodes) Presynaptic active zone network (Acanthochromis polyacanthus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	STX19	Syntaxin 19. (299 aa)
	ENSAPOP00000024219	Guanylate cyclase domain-containing protein. (124 aa)
	UNC13B	Unc-13 homolog B. (1596 aa)
	rims3	Regulating synaptic membrane exocytosis 3. (324 aa)
	ENSAPOP00000016038	C2 domain-containing protein. (284 aa)
	ENSAPOP00000016008	PDZ domain-containing protein. (354 aa)
	LOC110957865	Uncharacterized protein. (1096 aa)
	LOC110963314	Uncharacterized protein. (934 aa)
	CDH2	Cadherin 2; Cadherins are calcium-dependent cell adhesion proteins. (910 aa)
	adcy8	Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1181 aa)
	UNC13C	Unc-13 homolog C. (2579 aa)
	ENSAPOP00000032527	G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (371 aa)
	LOC110956638	Si:cabz01090165.1. (660 aa)
	LOC110971754	Uncharacterized protein. (314 aa)
	RIMS2	Regulating synaptic membrane exocytosis 2. (1300 aa)
	stx1b	Syntaxin 1B; Belongs to the syntaxin family. (291 aa)
	ENSAPOP00000028373	Zf-piccolo domain-containing protein. (582 aa)
	erc1	ELKS/RAB6-interacting/CAST family member 1a. (1093 aa)
	PCLO	Piccolo presynaptic cytomatrix protein b. (6314 aa)
	ENSAPOP00000028008	Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (329 aa)
	ENSAPOP00000027021	Syntaxin 11a; Belongs to the syntaxin family. (319 aa)
	ENSAPOP00000026992	t-SNARE coiled-coil homology domain-containing protein. (292 aa)
	LOC110950387	Uncharacterized protein. (278 aa)
	LOC110968688	t-SNARE coiled-coil homology domain-containing protein; Belongs to the syntaxin family. (289 aa)
	LOC110949342	Cadherin 2, type 1, N-cadherin (neuronal); Cadherins are calcium-dependent cell adhesion proteins. (916 aa)
	STX3	Syntaxin 3; Belongs to the syntaxin family. (313 aa)
	LOC110951460	Syntaxin 4; Belongs to the syntaxin family. (296 aa)
	LOC110959330	Zgc:172282. (698 aa)
	ENSAPOP00000012135	C2 domain-containing protein. (260 aa)
	LOC110956834	Piccolo presynaptic cytomatrix protein a. (2412 aa)
	rims4	Regulating synaptic membrane exocytosis 4. (271 aa)
	UNC13A	Unc-13 homolog A. (1876 aa)
	stx1a	Syntaxin 1A (brain); Belongs to the syntaxin family. (302 aa)
	LOC110962432	Uncharacterized protein. (1263 aa)
	LOC110949357	Uncharacterized protein. (1828 aa)
	RIMS1	Regulating synaptic membrane exocytosis 1. (1473 aa)
	zzef1	Zinc finger, ZZ-type with EF hand domain 1. (3004 aa)
	LOC110956487	Regulating synaptic membrane exocytosis 1a. (1379 aa)
	LOC110955259	Bassoon (presynaptic cytomatrix protein) b. (3927 aa)
	erc2	ELKS/RAB6-interacting/CAST family member 2. (970 aa)
	LOC110950537	Syntaxin 2b; Belongs to the syntaxin family. (291 aa)
	LOC110967147	Complexin 3b. (156 aa)
	nptn	Neuroplastin b. (391 aa)
	ENSAPOP00000006602	t-SNARE coiled-coil homology domain-containing protein; Belongs to the syntaxin family. (301 aa)
	ENSAPOP00000006627	t-SNARE coiled-coil homology domain-containing protein. (292 aa)
	LOC110955793	Nectin cell adhesion molecule 1b. (499 aa)
	LOC110960429	Zf-piccolo domain-containing protein. (3778 aa)

Your Current Organism:

Acanthochromis polyacanthus

NCBI taxonomy Id: 80966
Other names: A. polyacanthus, Acanthochromis polyacathus, spiny chromis, spiny damselfish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDH2	LOC110949342	ENSAPOP00000033999	ENSAPOP00000025774	Cadherin 2; Cadherins are calcium-dependent cell adhesion proteins.	Cadherin 2, type 1, N-cadherin (neuronal); Cadherins are calcium-dependent cell adhesion proteins.	0.894
ENSAPOP00000006602	ENSAPOP00000006627	ENSAPOP00000006602	ENSAPOP00000006627	t-SNARE coiled-coil homology domain-containing protein; Belongs to the syntaxin family.	t-SNARE coiled-coil homology domain-containing protein.	0.754
ENSAPOP00000006602	ENSAPOP00000016008	ENSAPOP00000006602	ENSAPOP00000016008	t-SNARE coiled-coil homology domain-containing protein; Belongs to the syntaxin family.	PDZ domain-containing protein.	0.837
ENSAPOP00000006602	LOC110949357	ENSAPOP00000006602	ENSAPOP00000023156	t-SNARE coiled-coil homology domain-containing protein; Belongs to the syntaxin family.	Uncharacterized protein.	0.569
ENSAPOP00000006602	LOC110962432	ENSAPOP00000006602	ENSAPOP00000019303	t-SNARE coiled-coil homology domain-containing protein; Belongs to the syntaxin family.	Uncharacterized protein.	0.569
ENSAPOP00000006602	LOC110971754	ENSAPOP00000006602	ENSAPOP00000032189	t-SNARE coiled-coil homology domain-containing protein; Belongs to the syntaxin family.	Uncharacterized protein.	0.569
ENSAPOP00000006602	RIMS2	ENSAPOP00000006602	ENSAPOP00000031587	t-SNARE coiled-coil homology domain-containing protein; Belongs to the syntaxin family.	Regulating synaptic membrane exocytosis 2.	0.837
ENSAPOP00000006602	UNC13A	ENSAPOP00000006602	ENSAPOP00000020040	t-SNARE coiled-coil homology domain-containing protein; Belongs to the syntaxin family.	Unc-13 homolog A.	0.569
ENSAPOP00000006602	UNC13B	ENSAPOP00000006602	ENSAPOP00000024621	t-SNARE coiled-coil homology domain-containing protein; Belongs to the syntaxin family.	Unc-13 homolog B.	0.569
ENSAPOP00000006602	UNC13C	ENSAPOP00000006602	ENSAPOP00000033076	t-SNARE coiled-coil homology domain-containing protein; Belongs to the syntaxin family.	Unc-13 homolog C.	0.569
ENSAPOP00000006627	ENSAPOP00000006602	ENSAPOP00000006627	ENSAPOP00000006602	t-SNARE coiled-coil homology domain-containing protein.	t-SNARE coiled-coil homology domain-containing protein; Belongs to the syntaxin family.	0.754
ENSAPOP00000006627	ENSAPOP00000016008	ENSAPOP00000006627	ENSAPOP00000016008	t-SNARE coiled-coil homology domain-containing protein.	PDZ domain-containing protein.	0.837
ENSAPOP00000006627	ENSAPOP00000027021	ENSAPOP00000006627	ENSAPOP00000027021	t-SNARE coiled-coil homology domain-containing protein.	Syntaxin 11a; Belongs to the syntaxin family.	0.755
ENSAPOP00000006627	LOC110949357	ENSAPOP00000006627	ENSAPOP00000023156	t-SNARE coiled-coil homology domain-containing protein.	Uncharacterized protein.	0.569
ENSAPOP00000006627	LOC110962432	ENSAPOP00000006627	ENSAPOP00000019303	t-SNARE coiled-coil homology domain-containing protein.	Uncharacterized protein.	0.569
ENSAPOP00000006627	LOC110971754	ENSAPOP00000006627	ENSAPOP00000032189	t-SNARE coiled-coil homology domain-containing protein.	Uncharacterized protein.	0.569
ENSAPOP00000006627	RIMS2	ENSAPOP00000006627	ENSAPOP00000031587	t-SNARE coiled-coil homology domain-containing protein.	Regulating synaptic membrane exocytosis 2.	0.837
ENSAPOP00000006627	UNC13A	ENSAPOP00000006627	ENSAPOP00000020040	t-SNARE coiled-coil homology domain-containing protein.	Unc-13 homolog A.	0.569
ENSAPOP00000006627	UNC13B	ENSAPOP00000006627	ENSAPOP00000024621	t-SNARE coiled-coil homology domain-containing protein.	Unc-13 homolog B.	0.569
ENSAPOP00000006627	UNC13C	ENSAPOP00000006627	ENSAPOP00000033076	t-SNARE coiled-coil homology domain-containing protein.	Unc-13 homolog C.	0.569