132 items (Acanthochromis polyacanthus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	ENSAPOP00000027855	Uncharacterized protein. (295 aa)
	LOC110958739	Tyrosine-protein kinase. (550 aa)
	LOC110953021	V-ral simian leukemia viral oncogene homolog Ba (ras related). (207 aa)
	LOC110968902	Uncharacterized protein. (201 aa)
	LOC110949965	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (385 aa)
	LOC110963602	Tyrosine-protein kinase receptor. (830 aa)
	LOC110956438	MAPK activated protein kinase 2b; Belongs to the protein kinase superfamily. (381 aa)
	LOC110955923	Tyrosine-protein kinase. (537 aa)
	LOC110967161	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (383 aa)
	LOC110954656	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (215 aa)
	LOC110948871	BHLH domain-containing protein. (464 aa)
	ENSAPOP00000003516	NTPase, KAP family P-loop domain containing 1. (700 aa)
	LOC110950007	Mitogen-activated protein kinase kinase 2a; Belongs to the protein kinase superfamily. (407 aa)
	irs2	Insulin receptor substrate 2b. (1124 aa)
	ENSAPOP00000004652	Uncharacterized protein. (265 aa)
	LOC110952243	Insulin receptor substrate 2a. (1060 aa)
	LOC110958051	P/Homo B domain-containing protein; Belongs to the peptidase S8 family. (625 aa)
	pik3cb	Phosphatidylinositol-4,5-bisphosphate 3-kinase, catalytic subunit beta; Belongs to the PI3/PI4-kinase family. (1079 aa)
	map2k5	Mitogen-activated protein kinase kinase 5; Belongs to the protein kinase superfamily. (438 aa)
	map2k1	Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (395 aa)
	ntrk1	Tyrosine-protein kinase receptor. (802 aa)
	DOCK3	Dedicator of cytokinesis 3; Belongs to the DOCK family. (1861 aa)
	ENSAPOP00000007916	Uncharacterized protein. (297 aa)
	LOC110957390	Dual specificity protein phosphatase; Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (369 aa)
	MAPKAPK2	MAPK activated protein kinase 2; Belongs to the protein kinase superfamily. (391 aa)
	ENSAPOP00000009302	Protein phosphatase 4, regulatory subunit 1-like. (188 aa)
	LOC110949785	Ribosomal protein S6 kinase. (746 aa)
	ENSAPOP00000009334	Uncharacterized protein. (224 aa)
	ENSAPOP00000009378	Uncharacterized protein. (216 aa)
	LOC110959164	Furin (paired basic amino acid cleaving enzyme) a; Belongs to the peptidase S8 family. (815 aa)
	shc2	SHC (Src homology 2 domain containing) transforming protein 2. (473 aa)
	creb1	Uncharacterized protein. (339 aa)
	mapk1	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (369 aa)
	kidins220	ANK_REP_REGION domain-containing protein. (1713 aa)
	AP2M1	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...] (442 aa)
	trib2	Tribbles pseudokinase 2. (345 aa)
	DUSP6	Dual specificity protein phosphatase 6-like. (383 aa)
	ENSAPOP00000011034	CHDCT2 domain-containing protein. (239 aa)
	ENSAPOP00000011062	PHD-type domain-containing protein. (131 aa)
	LOC110969868	Protein kinase domain-containing protein. (682 aa)
	LOC110959765	Uncharacterized protein. (363 aa)
	LOC110952915	Ribosomal protein S6 kinase. (735 aa)
	LOC110958411	Ribosomal protein S6 kinase. (784 aa)
	LOC110947990	Mitogen-activated protein kinase. (361 aa)
	CSDE1	Cold shock domain containing E1, RNA-binding. (868 aa)
	LOC110955582	Nerve growth factor b (beta polypeptide); Belongs to the NGF-beta family. (193 aa)
	rala	V-ral simian leukemia viral oncogene homolog Aa (ras related). (206 aa)
	LOC110956114	Mitogen-activated protein kinase. (361 aa)
	ntrk3	Tyrosine-protein kinase receptor. (802 aa)
	ap2s1	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family. (142 aa)
	relch	RAB11 binding and LisH domain, coiled-coil and HEAT repeat containing. (1192 aa)
	LOC110949617	Nerve growth factor a (beta polypeptide); Belongs to the NGF-beta family. (296 aa)
	mapk15	Mitogen-activated protein kinase. (609 aa)
	LOC110953693	Tribbles pseudokinase 1. (356 aa)
	ENSAPOP00000016885	Uncharacterized protein. (71 aa)
	LOC110965492	Dual specificity protein phosphatase 6-like. (383 aa)
	SHC3	SHC adaptor protein 3. (673 aa)
	mapk7	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (1116 aa)
	LOC110955463	Dual specificity protein phosphatase; Dual specificity phosphatase able to dephosphorylate phosphotyrosine, phosphoserine and phosphothreonine residues, with a preference for phosphotyrosine as a substrate. Belongs to the protein-tyrosine phosphatase family. Non- receptor class dual specificity subfamily. (205 aa)
	fnbp4	Formin binding protein 4. (897 aa)
	LOC110957734	Activating transcription factor 1. (311 aa)
	LOC110953137	Ribosomal protein S6 kinase. (808 aa)
	LOC110952530	Protein phosphatase 2, regulatory subunit A, beta b. (589 aa)
	srf	MADS-box domain-containing protein. (602 aa)
	rapgef1	Rap guanine nucleotide exchange factor (GEF) 1b. (1098 aa)
	ENSAPOP00000018634	Uncharacterized protein. (132 aa)
	LOC110968412	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (937 aa)
	LOC110966635	Uncharacterized protein. (322 aa)
	LOC110949518	Uncharacterized protein. (351 aa)
	ENSAPOP00000019999	Achaete-scute family bHLH transcription factor 1b. (187 aa)
	LOC110961237	ETS transcription factor ELK1. (604 aa)
	hras	HRas proto-oncogene, GTPase a. (189 aa)
	LOC110950712	JunD proto-oncogene, AP-1 transcription factor subunit. (299 aa)
	bax	BCL2 associated X, apoptosis regulator a. (192 aa)
	bdnf	Brain-derived neurotrophic factor; Promotes the survival of neuronal populations that are all located either in the central nervous system or directly connected to it; Belongs to the NGF-beta family. (319 aa)
	LOC110964154	Serine/threonine-protein phosphatase. (309 aa)
	LOC110948328	Tyrosine-protein kinase. (552 aa)
	nab1	NGFI-A binding protein 1a (EGR1 binding protein 1). (501 aa)
	LOC110969588	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1013 aa)
	LOC110967143	Mitogen-activated protein kinase kinase 2b. (395 aa)
	crkl	V-crk avian sarcoma virus CT10 oncogene homolog-like. (306 aa)
	fosl1	FOS-like antigen 1a. (347 aa)
	LOC110957498	Mitogen-activated protein kinase. (360 aa)
	LOC110959967	Tyrosine-protein kinase receptor. (803 aa)
	LOC110959971	Proprotein convertase subtilisin/kexin type 5a. (1077 aa)
	LOC110952860	cAMP responsive element binding protein 1. (318 aa)
	LOC110968168	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...] (358 aa)
	LOC110949854	Inhibitor of DNA binding 4. (141 aa)
	LOC110971396	Chromodomain helicase DNA binding protein 4a. (1807 aa)
	nab2	NGFI-A binding protein 2 (EGR1 binding protein 2). (498 aa)
	fndc3b	Fibronectin type III domain containing 3Ba. (1211 aa)
	furin	Furin (paired basic amino acid cleaving enzyme) b; Belongs to the peptidase S8 family. (840 aa)
	mapkapk3	Protein kinase domain-containing protein; Belongs to the protein kinase superfamily. (408 aa)
	ntrk2	Tyrosine-protein kinase receptor. (815 aa)
	LOC110966286	JunB proto-oncogene, AP-1 transcription factor subunit a. (331 aa)
	LOC110966887	Serine/threonine-protein phosphatase. (309 aa)
	ENSAPOP00000027341	SH2 domain-containing protein. (120 aa)
	egr1	Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (512 aa)
	LOC110968091	Kinase D-interacting substrate 220b. (1319 aa)
	ENSAPOP00000027503	Early growth response 3. (346 aa)
	MAPK1	Mitogen-activated protein kinase. (150 aa)
	ppp4r4	Protein phosphatase 4, regulatory subunit 4. (931 aa)
	LOC110961531	CRK proto-oncogene, adaptor protein. (315 aa)
	pcsk5	Proprotein convertase subtilisin/kexin type 5b; Belongs to the peptidase S8 family. (920 aa)
	LOC110960299	Zgc:55558. (187 aa)
	dnal4	Dynein light chain. (106 aa)
	ralgds	Ral guanine nucleotide dissociation stimulator. (869 aa)
	LOC110945879	Mitogen-activated protein kinase. (313 aa)
	LOC110952874	Inhibitor of DNA binding 3. (117 aa)
	kras	V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog. (189 aa)
	LOC110951491	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
	LOC110964599	Phosphatidylinositol 4,5-bisphosphate 3-kinase catalytic subunit. (1068 aa)
	ENSAPOP00000029823	annotation not available (297 aa)
	MAPKAPK3	MAPK activated protein kinase 3; Belongs to the protein kinase superfamily. (422 aa)
	ntf3	Neurotrophin-3; Seems to promote the survival of visceral and proprioceptive sensory neurons; Belongs to the NGF-beta family. (300 aa)
	plcg1	1-phosphatidylinositol 4,5-bisphosphate phosphodiesterase gamma; Mediates the production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3). Plays an important role in the regulation of intracellular signaling cascades. (1314 aa)
	LOC110965027	Uncharacterized protein; Belongs to the DOCK family. (1895 aa)
	LOC110950915	Mitogen-activated protein kinase. (364 aa)
	SRF	Serum response factor. (243 aa)
	ascl1	Achaete-scute family bHLH transcription factor 1a. (200 aa)
	LOC110956697	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (391 aa)
	LOC110951668	NGF domain-containing protein; Belongs to the NGF-beta family. (442 aa)
	LOC110970400	BZIP domain-containing protein. (103 aa)
	LOC110949073	Serine/threonine-protein phosphatase. (309 aa)
	egr2	Early growth response 2b. (444 aa)
	LOC110951350	AP complex subunit beta. (953 aa)
	clta	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (232 aa)
	LOC110967227	VRK serine/threonine kinase 3. (541 aa)
	fndc3a	Fibronectin type III domain containing 3A. (1245 aa)
	LOC110970959	Uncharacterized protein. (315 aa)
	JUND	BZIP domain-containing protein. (297 aa)
	LOC110961811	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (956 aa)

Your Current Organism:

Acanthochromis polyacanthus

NCBI taxonomy Id: 80966
Other names: A. polyacanthus, Acanthochromis polyacathus, spiny chromis, spiny damselfish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AP2M1	ENSAPOP00000003516	ENSAPOP00000010209	ENSAPOP00000003516	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]	NTPase, KAP family P-loop domain containing 1.	0.503
AP2M1	ENSAPOP00000018634	ENSAPOP00000010209	ENSAPOP00000018634	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]	Uncharacterized protein.	0.503
AP2M1	LOC110945879	ENSAPOP00000010209	ENSAPOP00000028293	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]	Mitogen-activated protein kinase.	0.582
AP2M1	LOC110947990	ENSAPOP00000010209	ENSAPOP00000012325	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]	Mitogen-activated protein kinase.	0.554
AP2M1	LOC110949518	ENSAPOP00000010209	ENSAPOP00000019560	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]	Uncharacterized protein.	0.655
AP2M1	LOC110950915	ENSAPOP00000010209	ENSAPOP00000030438	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]	Mitogen-activated protein kinase.	0.554
AP2M1	LOC110951350	ENSAPOP00000010209	ENSAPOP00000032773	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]	AP complex subunit beta.	0.995
AP2M1	LOC110952243	ENSAPOP00000010209	ENSAPOP00000004786	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]	Insulin receptor substrate 2a.	0.660
AP2M1	LOC110956114	ENSAPOP00000010209	ENSAPOP00000013715	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]	Mitogen-activated protein kinase.	0.554
AP2M1	LOC110956697	ENSAPOP00000010209	ENSAPOP00000031576	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]	Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily.	0.582
AP2M1	LOC110957498	ENSAPOP00000010209	ENSAPOP00000023966	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]	Mitogen-activated protein kinase.	0.554
AP2M1	LOC110959164	ENSAPOP00000010209	ENSAPOP00000009410	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]	Furin (paired basic amino acid cleaving enzyme) a; Belongs to the peptidase S8 family.	0.402
AP2M1	LOC110959765	ENSAPOP00000010209	ENSAPOP00000011190	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]	Uncharacterized protein.	0.655
AP2M1	LOC110959967	ENSAPOP00000010209	ENSAPOP00000024370	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]	Tyrosine-protein kinase receptor.	0.587
AP2M1	LOC110961811	ENSAPOP00000010209	ENSAPOP00000034767	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	0.996
AP2M1	LOC110963602	ENSAPOP00000010209	ENSAPOP00000001733	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]	Tyrosine-protein kinase receptor.	0.592
AP2M1	LOC110968091	ENSAPOP00000010209	ENSAPOP00000027499	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]	Kinase D-interacting substrate 220b.	0.503
AP2M1	LOC110968412	ENSAPOP00000010209	ENSAPOP00000019033	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	0.998
AP2M1	MAPK1	ENSAPOP00000010209	ENSAPOP00000027566	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]	Mitogen-activated protein kinase.	0.582
AP2M1	ap2s1	ENSAPOP00000010209	ENSAPOP00000014385	AP-2 complex subunit mu; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold but i [...]	AP complex subunit sigma; Belongs to the adaptor complexes small subunit family.	0.997