STRINGSTRING
prkca prkca LOC110962991 LOC110962991 rrad rrad LOC110958786 LOC110958786 LOC110951271 LOC110951271 plcb3 plcb3 mmp2 mmp2 map3k2 map3k2 LOC110951301 LOC110951301 MAPK10 MAPK10 ENSAPOP00000033966 ENSAPOP00000033966 LOC110968411 LOC110968411 LOC110964242 LOC110964242 adcy8 adcy8 LOC110956829 LOC110956829 LOC110961331 LOC110961331 LOC110961360 LOC110961360 LOC110955524 LOC110955524 LOC110966739 LOC110966739 LOC110956697 LOC110956697 LOC110953744 LOC110953744 sos2 sos2 LOC110950915 LOC110950915 adcy3 adcy3 GNAS GNAS map3k4 map3k4 prkcd prkcd ENSAPOP00000029641 ENSAPOP00000029641 ENSAPOP00000029410 ENSAPOP00000029410 kras kras ENSAPOP00000028556 ENSAPOP00000028556 LOC110945879 LOC110945879 itpr1 itpr1 LOC110960299 LOC110960299 ENSAPOP00000028008 ENSAPOP00000028008 LOC110965683 LOC110965683 LOC110948068 LOC110948068 MAPK1 MAPK1 ENSAPOP00000027492 ENSAPOP00000027492 egr1 egr1 LOC110972836 LOC110972836 LOC110963958 LOC110963958 LOC110972709 LOC110972709 calm2 calm2 ENSAPOP00000025798 ENSAPOP00000025798 LOC110966992 LOC110966992 LOC110949354 LOC110949354 ELK3 ELK3 LOC110961648 LOC110961648 ENSAPOP00000025035 ENSAPOP00000025035 map2k7 map2k7 ENSAPOP00000024219 ENSAPOP00000024219 LOC110948199 LOC110948199 LOC110957498 LOC110957498 LOC110952258 LOC110952258 LOC110967601 LOC110967601 LOC110967143 LOC110967143 LOC110961753 LOC110961753 adcy6 adcy6 LOC110952988 LOC110952988 gnrh2 gnrh2 grb2 grb2 LOC110962918 LOC110962918 LOC110970209 LOC110970209 LOC110948328 LOC110948328 LOC110954136 LOC110954136 ptk2b ptk2b LOC110948379 LOC110948379 LOC110966592 LOC110966592 CALML6 CALML6 hras hras LOC110961237 LOC110961237 ENSAPOP00000019975 ENSAPOP00000019975 calml4 calml4 jun jun adcy7 adcy7 LOC110966030 LOC110966030 ENSAPOP00000018743 ENSAPOP00000018743 LOC110950870 LOC110950870 LOC110954831 LOC110954831 ENSAPOP00000018108 ENSAPOP00000018108 LOC110969104 LOC110969104 LOC110969744 LOC110969744 mapk7 mapk7 ENSAPOP00000017140 ENSAPOP00000017140 ptx3 ptx3 PLCB1 PLCB1 PLCB4 PLCB4 jmjd7 jmjd7 LOC110967325 LOC110967325 ADCY9 ADCY9 LOC110964357 LOC110964357 REM1 REM1 map3k3 map3k3 pla2g4a pla2g4a sos1 sos1 camk2b camk2b LOC110945652 LOC110945652 calm3 calm3 LOC110952174 LOC110952174 LOC110956114 LOC110956114 LOC110954952 LOC110954952 CSDE1 CSDE1 LOC110964431 LOC110964431 LOC110956797 LOC110956797 LOC110953261 LOC110953261 LOC110947988 LOC110947988 LOC110947990 LOC110947990 LOC110955660 LOC110955660 ENSAPOP00000012033 ENSAPOP00000012033 LOC110969860 LOC110969860 LOC110966235 LOC110966235 LOC110959104 LOC110959104 cga cga LOC110962674 LOC110962674 ENSAPOP00000010108 ENSAPOP00000010108 mapk1 mapk1 LOC110972832 LOC110972832 LOC110960961 LOC110960961 PLCB2 PLCB2 raf1 raf1 LOC110952161 LOC110952161 CACNA1D CACNA1D prkaca prkaca mapk9 mapk9 CDC42 CDC42 LOC110952819 LOC110952819 LOC110957424 LOC110957424 calm1 calm1 map2k1 map2k1 LOC110964677 LOC110964677 LOC110958600 LOC110958600 LOC110959963 LOC110959963 LOC110959965 LOC110959965 LOC110954028 LOC110954028 LOC110962298 LOC110962298 LOC110970701 LOC110970701 ENSAPOP00000003754 ENSAPOP00000003754 LOC110950007 LOC110950007 MAP2K6 MAP2K6 cacna1s cacna1s LOC110949917 LOC110949917 LOC110946172 LOC110946172 ENSAPOP00000003112 ENSAPOP00000003112 LOC110955249 LOC110955249 LOC110965885 LOC110965885 ENSAPOP00000002611 ENSAPOP00000002611 LOC110962375 LOC110962375 LOC110962897 LOC110962897 gnrh1 gnrh1 LOC110952319 LOC110952319 map2k4 map2k4 LOC110955296 LOC110955296 adcy2 adcy2 LOC110947218 LOC110947218 LOC110961813 LOC110961813 LOC110958739 LOC110958739 LOC110958191 LOC110958191
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
prkcaProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (687 aa)
LOC110962991Guanine nucleotide binding protein (G protein), alpha 11b (Gq class). (359 aa)
rradRas-related associated with diabetes. (309 aa)
LOC110958786Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (667 aa)
LOC110951271Cell division cycle 42. (191 aa)
plcb31-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1257 aa)
mmp2Matrix metallopeptidase 2. (658 aa)
map3k2Mitogen-activated protein kinase kinase kinase 2. (647 aa)
LOC110951301Guanine nucleotide binding protein (G protein), alpha 11a (Gq class). (359 aa)
MAPK10Mitogen-activated protein kinase. (236 aa)
ENSAPOP00000033966Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1041 aa)
LOC110968411ETS domain-containing protein. (489 aa)
LOC110964242Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1153 aa)
adcy8Adenylate cyclase type 8; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1181 aa)
LOC110956829GNAS complex locus. (379 aa)
LOC110961331Mitogen-activated protein kinase. (212 aa)
LOC110961360Uncharacterized protein. (191 aa)
LOC110955524Inositol 1,4,5-trisphosphate receptor, type 2. (1988 aa)
LOC110966739Matrix metallopeptidase 14a (membrane-inserted). (560 aa)
LOC110956697Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (391 aa)
LOC110953744Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (963 aa)
sos2Son of sevenless homolog 2 (Drosophila). (1310 aa)
LOC110950915Mitogen-activated protein kinase. (364 aa)
adcy3Adenylate cyclase type 3; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1123 aa)
GNASGNAS complex locus. (379 aa)
map3k4Mitogen-activated protein kinase kinase kinase 4. (1593 aa)
prkcdProtein kinase C delta type; Calcium-independent, phospholipid- and diacylglycerol (DAG)- dependent serine/threonine-protein kinase that plays contrasting roles in cell death and cell survival by functioning as a pro-apoptotic protein during DNA damage-induced apoptosis, but acting as an anti- apoptotic protein during cytokine receptor-initiated cell death, is involved in tumor suppression; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (684 aa)
ENSAPOP00000029641AGC-kinase C-terminal domain-containing protein. (57 aa)
ENSAPOP00000029410Ion_trans domain-containing protein. (194 aa)
krasV-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog. (189 aa)
ENSAPOP00000028556Receptor protein-tyrosine kinase. (1194 aa)
LOC110945879Mitogen-activated protein kinase. (313 aa)
itpr1Inositol 1,4,5-trisphosphate receptor, type 1b. (2726 aa)
LOC110960299Zgc:55558. (187 aa)
ENSAPOP00000028008Guanylate cyclase domain-containing protein; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (329 aa)
LOC110965683Calcium/calmodulin-dependent protein kinase (CaM kinase) II delta 2. (519 aa)
LOC110948068Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1468 aa)
MAPK1Mitogen-activated protein kinase. (150 aa)
ENSAPOP00000027492Ion_trans domain-containing protein. (150 aa)
egr1Early growth response protein; Transcriptional regulator. Recognizes and binds to the DNA sequence 5'-GCG(T/G)GGGCG-3'(EGR-site) in the promoter region of target genes. Binds double-stranded target DNA, irrespective of the cytosine methylation status. Regulates the transcription of numerous target genes, and thereby plays an important role in regulating the response to growth factors, DNA damage, and ischemia. Plays a role in the regulation of cell survival, proliferation and cell death. Belongs to the EGR C2H2-type zinc-finger protein family. (512 aa)
LOC110972836Gonadotropin-releasing hormone II receptor-like. (381 aa)
LOC1109639581-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1162 aa)
LOC110972709Phospholipase. (1054 aa)
calm2Calmodulin 2. (149 aa)
ENSAPOP00000025798Protein kinase, cAMP-dependent, catalytic, beta a; Belongs to the protein kinase superfamily. (351 aa)
LOC110966992Mitogen-activated protein kinase kinase 6. (353 aa)
LOC110949354G_PROTEIN_RECEP_F1_2 domain-containing protein. (390 aa)
ELK3ETS transcription factor ELK3. (402 aa)
LOC110961648Phosphoinositide phospholipase C. (403 aa)
ENSAPOP00000025035G_PROTEIN_RECEP_F1_2 domain-containing protein. (108 aa)
map2k7Mitogen-activated protein kinase kinase 7. (423 aa)
ENSAPOP00000024219Guanylate cyclase domain-containing protein. (124 aa)
LOC110948199Mitogen-activated protein kinase. (296 aa)
LOC110957498Mitogen-activated protein kinase. (360 aa)
LOC110952258Protein kinase domain-containing protein. (543 aa)
LOC110967601Mitogen-activated protein kinase 8b. (307 aa)
LOC110967143Mitogen-activated protein kinase kinase 2b. (395 aa)
LOC110961753Adenylate cyclase type 5; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1154 aa)
adcy6Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1207 aa)
LOC110952988Mitogen-activated protein kinase kinase 4b; Belongs to the protein kinase superfamily. (435 aa)
gnrh2Gonadoliberin; Stimulates the secretion of gonadotropins. Belongs to the GnRH family. (85 aa)
grb2Growth factor receptor-bound protein 2b. (217 aa)
LOC110962918Mitogen-activated protein kinase 10. (268 aa)
LOC110970209Luteinizing hormone, beta polypeptide. (139 aa)
LOC110948328Tyrosine-protein kinase. (552 aa)
LOC110954136GRB2 related adaptor protein 2a. (284 aa)
ptk2bProtein tyrosine kinase 2 beta, b; Belongs to the protein kinase superfamily. Tyr protein kinase family. (912 aa)
LOC110948379Protein kinase domain-containing protein. (569 aa)
LOC110966592Mitogen-activated protein kinase kinase kinase 22. (624 aa)
CALML6Calmodulin like 6. (153 aa)
hrasHRas proto-oncogene, GTPase a. (189 aa)
LOC110961237ETS transcription factor ELK1. (604 aa)
ENSAPOP00000019975MIR domain-containing protein. (221 aa)
calml4Calmodulin-like 4a. (153 aa)
junBZIP domain-containing protein; Belongs to the bZIP family. (323 aa)
adcy7Adenylate cyclase type 7; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1093 aa)
LOC110966030Uncharacterized protein; Belongs to the protein kinase superfamily. (380 aa)
ENSAPOP00000018743Gonadoliberin; Stimulates the secretion of gonadotropins. Belongs to the GnRH family. (92 aa)
LOC110950870Uncharacterized protein. (359 aa)
LOC110954831G_PROTEIN_RECEP_F1_2 domain-containing protein. (424 aa)
ENSAPOP00000018108G_PROTEIN_RECEP_F1_2 domain-containing protein. (365 aa)
LOC110969104Calcium/calmodulin-dependent protein kinase II alpha; Belongs to the protein kinase superfamily. (478 aa)
LOC110969744Protein kinase domain-containing protein. (192 aa)
mapk7Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (1116 aa)
ENSAPOP00000017140JunE proto-oncogene, AP-1 transcription factor subunit. (340 aa)
ptx3Pentraxin 3, long b. (461 aa)
PLCB1Phosphoinositide phospholipase C. (583 aa)
PLCB41-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1241 aa)
jmjd7Jumonji domain containing 7. (316 aa)
LOC110967325Uncharacterized protein. (1301 aa)
ADCY9Adenylate cyclase 9; Belongs to the adenylyl cyclase class-4/guanylyl cyclase family. (1440 aa)
LOC110964357Calcium/calmodulin-dependent protein kinase (CaM kinase) II beta 2. (343 aa)
REM1RRAD and GEM like GTPase 1. (309 aa)
map3k3Mitogen-activated protein kinase kinase kinase 3. (623 aa)
pla2g4aPhospholipase A2. (749 aa)
sos1Son of sevenless homolog 1 (Drosophila). (1152 aa)
camk2bCalcium/calmodulin-dependent protein kinase (CaM kinase) II beta 2. (539 aa)
LOC110945652Cyclic AMP-dependent transcription factor ATF-4-like. (438 aa)
calm3Calmodulin 3. (149 aa)
LOC110952174Heparin-binding EGF-like growth factor a. (240 aa)
LOC110956114Mitogen-activated protein kinase. (361 aa)
LOC110954952Protein kinase C, gamma; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (851 aa)
CSDE1Cold shock domain containing E1, RNA-binding. (868 aa)
LOC110964431Ion_trans domain-containing protein. (482 aa)
LOC110956797Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (657 aa)
LOC110953261Matrix metallopeptidase 14b (membrane-inserted). (628 aa)
LOC110947988Mitogen-activated protein kinase. (360 aa)
LOC110947990Mitogen-activated protein kinase. (361 aa)
LOC110955660Adenylate cyclase type 1; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1127 aa)
ENSAPOP00000012033Ion_trans domain-containing protein. (466 aa)
LOC110969860GRB2 related adaptor protein 2b. (287 aa)
LOC110966235Cell division cycle 42, like. (191 aa)
LOC110959104Mitogen-activated protein kinase. (464 aa)
cgaGlycoprotein hormones alpha chain; Belongs to the glycoprotein hormones subunit alpha family. (124 aa)
LOC110962674Mitogen-activated protein kinase. (363 aa)
ENSAPOP00000010108Uncharacterized protein. (130 aa)
mapk1Mitogen-activated protein kinase; Belongs to the protein kinase superfamily. Ser/Thr protein kinase family. MAP kinase subfamily. (369 aa)
LOC110972832G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (381 aa)
LOC110960961Inositol 1,4,5-trisphosphate receptor, type 1a. (1966 aa)
PLCB21-phosphatidylinositol 4,5-bisphosphate phosphodiesterase; The production of the second messenger molecules diacylglycerol (DAG) and inositol 1,4,5-trisphosphate (IP3) is mediated by activated phosphatidylinositol-specific phospholipase C enzymes. (1208 aa)
raf1Raf-1 proto-oncogene, serine/threonine kinase a. (655 aa)
LOC110952161Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (681 aa)
CACNA1DVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1963 aa)
prkacaProtein kinase, cAMP-dependent, catalytic, alpha, genome duplicate b; Belongs to the protein kinase superfamily. (351 aa)
mapk9Mitogen-activated protein kinase. (420 aa)
CDC42Cell division cycle 42. (191 aa)
LOC110952819Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (2140 aa)
LOC110957424Protein kinase domain-containing protein. (560 aa)
calm1Calmodulin 1. (149 aa)
map2k1Mitogen-activated protein kinase kinase 1; Belongs to the protein kinase superfamily. (395 aa)
LOC110964677Activating transcription factor 4b. (435 aa)
LOC110958600Adenylate cyclase type 6; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1144 aa)
LOC110959963Uncharacterized protein. (354 aa)
LOC110959965Uncharacterized protein. (359 aa)
LOC110954028Cys_knot domain-containing protein. (195 aa)
LOC110962298Calmodulin 2a (phosphorylase kinase, delta); Belongs to the calmodulin family. (149 aa)
LOC110970701Receptor protein-tyrosine kinase. (1070 aa)
ENSAPOP00000003754EF-hand domain-containing protein. (282 aa)
LOC110950007Mitogen-activated protein kinase kinase 2a; Belongs to the protein kinase superfamily. (407 aa)
MAP2K6Mitogen-activated protein kinase kinase 6. (345 aa)
cacna1sVoltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1777 aa)
LOC110949917Uncharacterized protein. (484 aa)
LOC110946172Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1821 aa)
ENSAPOP00000003112Calcium channel, voltage-dependent, L type, alpha 1D subunit, b. (101 aa)
LOC110955249Voltage-dependent L-type calcium channel subunit alpha; Voltage-sensitive calcium channels (VSCC) mediate the entry of calcium ions into excitable cells and are also involved in a variety of calcium-dependent processes, including muscle contraction, hormone or neurotransmitter release, gene expression, cell motility, cell division and cell death; Belongs to the calcium channel alpha-1 subunit (TC 1.A.1.11) family. (1581 aa)
LOC110965885Activating transcription factor 4a. (438 aa)
ENSAPOP00000002611Phorbol-ester/DAG-type domain-containing protein. (60 aa)
LOC110962375Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. (900 aa)
LOC110962897Protein kinase, cAMP-dependent, catalytic, alpha, genome duplicate a; Belongs to the protein kinase superfamily. (388 aa)
gnrh1Uncharacterized protein. (99 aa)
LOC110952319Jun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (291 aa)
map2k4Mitogen-activated protein kinase kinase 4; Belongs to the protein kinase superfamily. (433 aa)
LOC110955296Protein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (681 aa)
adcy2Adenylate cyclase type 2; Catalyzes the formation of the signaling molecule cAMP in response to G-protein signaling. (1117 aa)
LOC110947218Phospholipase. (954 aa)
LOC110961813G_PROTEIN_RECEP_F1_2 domain-containing protein. (400 aa)
LOC110958739Tyrosine-protein kinase. (550 aa)
LOC110958191Phospholipase. (1038 aa)
Your Current Organism:
Acanthochromis polyacanthus
NCBI taxonomy Id: 80966
Other names: A. polyacanthus, Acanthochromis polyacathus, spiny chromis, spiny damselfish
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