(47 nodes) Small nuclear ribonucleoprotein complex network (Amphiprion ocellaris)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	sf3a1	Splicing factor 3a, subunit 1. (786 aa)
	lsm6	LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated. (155 aa)
	snrpa	Small nuclear ribonucleoprotein polypeptide A. (282 aa)
	snrpb2	Small nuclear ribonucleoprotein polypeptide B2. (218 aa)
	snrpg	Small nuclear ribonucleoprotein G. (76 aa)
	snrpa1	Small nuclear ribonucleoprotein polypeptide A. (287 aa)
	snrpb	Small nuclear ribonucleoprotein-associated protein. (240 aa)
	sf3b3	Splicing factor 3b, subunit 3. (1217 aa)
	snrpd1	Small nuclear ribonucleoprotein Sm D1; Essential for pre-mRNA splicing. Implicated in the formation of stable, biologically active snRNP structures. Belongs to the snRNP core protein family. (119 aa)
	lsm3	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (102 aa)
	Snrnp35	Small nuclear ribonucleoprotein 35 (U11/U12). (214 aa)
	SNRPD3	Small nuclear ribonucleoprotein Sm D3. (127 aa)
	prpf3	PRP3 pre-mRNA processing factor 3 homolog (yeast). (698 aa)
	prpf6	PRP6 pre-mRNA processing factor 6 homolog (S. cerevisiae). (969 aa)
	sf3a3	Splicing factor 3a, subunit 3. (501 aa)
	lsm8	U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA. (96 aa)
	sart3	Spliceosome associated factor 3, U4/U6 recycling protein. (946 aa)
	Snrpf	Small nuclear ribonucleoprotein polypeptide F. (85 aa)
	lsm7	LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated. (132 aa)
	LSM10	LSM10, U7 small nuclear RNA associated. (121 aa)
	LOC111582252	Small nuclear ribonucleoprotein Sm D3. (108 aa)
	ddx23	DEAD (Asp-Glu-Ala-Asp) box polypeptide 23. (806 aa)
	txnl4a	Thioredoxin-like protein; Plays role in pre-mRNA splicing. Belongs to the DIM1 family. (142 aa)
	sf3b4	Splicing factor 3b, subunit 4. (400 aa)
	phf5a	PHD finger protein 5A. (110 aa)
	snrpc	U1 small nuclear ribonucleoprotein C; Component of the spliceosomal U1 snRNP, which is essential for recognition of the pre-mRNA 5' splice-site and the subsequent assembly of the spliceosome. SNRPC/U1-C is directly involved in initial 5' splice-site recognition for both constitutive and regulated alternative splicing. The interaction with the 5' splice-site seems to precede base-pairing between the pre-mRNA and the U1 snRNA. Stimulates commitment or early (E) complex formation by stabilizing the base pairing of the 5' end of the U1 snRNA and the 5' splice-site region. Belongs to the U1 [...] (148 aa)
	LOC111573911	Small nuclear ribonucleoprotein Sm D3. (127 aa)
	lsm5	U6 snRNA-associated Sm-like protein LSm5; Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA. (91 aa)
	sf3b5	Splicing factor 3B subunit 5; Belongs to the SF3B5 family. (86 aa)
	snrpe	Small nuclear ribonucleoprotein E; Associated with the spliceosome snRNP U1, U2, U4/U6 and U5. Belongs to the snRNP Sm proteins family. (92 aa)
	snrpd2	Small nuclear ribonucleoprotein Sm D2. (118 aa)
	sart1	Spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP. (773 aa)
	ddx42	DEAD (Asp-Glu-Ala-Asp) box helicase 42. (919 aa)
	snrnp40	Small nuclear ribonucleoprotein 40 (U5). (347 aa)
	sf3b1	Splicing factor 3b, subunit 1. (1315 aa)
	prpf4	PRP4 pre-mRNA processing factor 4 homolog (yeast). (510 aa)
	lsm4	U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (148 aa)
	lsm2	U6 snRNA-associated Sm-like protein LSm2; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (121 aa)
	ddx46	DEAD (Asp-Glu-Ala-Asp) box polypeptide 46. (1062 aa)
	sf3b2	Splicing factor 3b, subunit 2. (877 aa)
	prpf8	Pre-mRNA processing factor 8. (2338 aa)
	sf3b6	Splicing factor 3b, subunit 6. (125 aa)
	ENSAOCP00000027008	Sm domain-containing protein. (129 aa)
	sf3a2	Splicing factor 3a, subunit 2. (304 aa)
	prpf31	PRP31 pre-mRNA processing factor 31 homolog (yeast). (536 aa)
	eftud2	Elongation factor Tu GTP binding domain containing 2. (817 aa)
	snrnp200	Small nuclear ribonucleoprotein 200 (U5). (2136 aa)

Your Current Organism:

Amphiprion ocellaris

NCBI taxonomy Id: 80972
Other names: A. ocellaris, clown anemonefish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSAOCP00000027008	LOC111573911	ENSAOCP00000027008	ENSAOCP00000017383	Sm domain-containing protein.	Small nuclear ribonucleoprotein Sm D3.	0.873
ENSAOCP00000027008	LOC111582252	ENSAOCP00000027008	ENSAOCP00000012329	Sm domain-containing protein.	Small nuclear ribonucleoprotein Sm D3.	0.873
ENSAOCP00000027008	SNRPD3	ENSAOCP00000027008	ENSAOCP00000005047	Sm domain-containing protein.	Small nuclear ribonucleoprotein Sm D3.	0.873
ENSAOCP00000027008	Snrnp35	ENSAOCP00000027008	ENSAOCP00000004297	Sm domain-containing protein.	Small nuclear ribonucleoprotein 35 (U11/U12).	0.824
ENSAOCP00000027008	Snrpf	ENSAOCP00000027008	ENSAOCP00000010880	Sm domain-containing protein.	Small nuclear ribonucleoprotein polypeptide F.	0.985
ENSAOCP00000027008	ddx23	ENSAOCP00000027008	ENSAOCP00000012838	Sm domain-containing protein.	DEAD (Asp-Glu-Ala-Asp) box polypeptide 23.	0.906
ENSAOCP00000027008	ddx42	ENSAOCP00000027008	ENSAOCP00000019854	Sm domain-containing protein.	DEAD (Asp-Glu-Ala-Asp) box helicase 42.	0.639
ENSAOCP00000027008	ddx46	ENSAOCP00000027008	ENSAOCP00000022310	Sm domain-containing protein.	DEAD (Asp-Glu-Ala-Asp) box polypeptide 46.	0.901
ENSAOCP00000027008	eftud2	ENSAOCP00000027008	ENSAOCP00000031591	Sm domain-containing protein.	Elongation factor Tu GTP binding domain containing 2.	0.932
ENSAOCP00000027008	lsm2	ENSAOCP00000027008	ENSAOCP00000021866	Sm domain-containing protein.	U6 snRNA-associated Sm-like protein LSm2; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	0.909
ENSAOCP00000027008	lsm3	ENSAOCP00000027008	ENSAOCP00000004261	Sm domain-containing protein.	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	0.801
ENSAOCP00000027008	lsm4	ENSAOCP00000027008	ENSAOCP00000021542	Sm domain-containing protein.	U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	0.893
ENSAOCP00000027008	lsm5	ENSAOCP00000027008	ENSAOCP00000017403	Sm domain-containing protein.	U6 snRNA-associated Sm-like protein LSm5; Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA.	0.866
ENSAOCP00000027008	lsm6	ENSAOCP00000027008	ENSAOCP00000000258	Sm domain-containing protein.	LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated.	0.888
ENSAOCP00000027008	lsm7	ENSAOCP00000027008	ENSAOCP00000011290	Sm domain-containing protein.	LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated.	0.906
ENSAOCP00000027008	lsm8	ENSAOCP00000027008	ENSAOCP00000009751	Sm domain-containing protein.	U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.	0.897
ENSAOCP00000027008	phf5a	ENSAOCP00000027008	ENSAOCP00000016067	Sm domain-containing protein.	PHD finger protein 5A.	0.883
ENSAOCP00000027008	prpf3	ENSAOCP00000027008	ENSAOCP00000007605	Sm domain-containing protein.	PRP3 pre-mRNA processing factor 3 homolog (yeast).	0.846
ENSAOCP00000027008	prpf31	ENSAOCP00000027008	ENSAOCP00000030366	Sm domain-containing protein.	PRP31 pre-mRNA processing factor 31 homolog (yeast).	0.848
ENSAOCP00000027008	prpf4	ENSAOCP00000027008	ENSAOCP00000021006	Sm domain-containing protein.	PRP4 pre-mRNA processing factor 4 homolog (yeast).	0.606