(19 nodes) U4/U6 x U5 tri-snRNP complex network (Amphiprion ocellaris)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	lsm6	LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated. (155 aa)
	lsm3	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (102 aa)
	prpf3	PRP3 pre-mRNA processing factor 3 homolog (yeast). (698 aa)
	prpf6	PRP6 pre-mRNA processing factor 6 homolog (S. cerevisiae). (969 aa)
	lsm8	U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA. (96 aa)
	sart3	Spliceosome associated factor 3, U4/U6 recycling protein. (946 aa)
	lsm7	LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated. (132 aa)
	ddx23	DEAD (Asp-Glu-Ala-Asp) box polypeptide 23. (806 aa)
	txnl4a	Thioredoxin-like protein; Plays role in pre-mRNA splicing. Belongs to the DIM1 family. (142 aa)
	lsm5	U6 snRNA-associated Sm-like protein LSm5; Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA. (91 aa)
	sart1	Spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP. (773 aa)
	snrnp40	Small nuclear ribonucleoprotein 40 (U5). (347 aa)
	prpf4	PRP4 pre-mRNA processing factor 4 homolog (yeast). (510 aa)
	lsm4	U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (148 aa)
	lsm2	U6 snRNA-associated Sm-like protein LSm2; Binds specifically to the 3'-terminal U-tract of U6 snRNA. (121 aa)
	prpf8	Pre-mRNA processing factor 8. (2338 aa)
	prpf31	PRP31 pre-mRNA processing factor 31 homolog (yeast). (536 aa)
	eftud2	Elongation factor Tu GTP binding domain containing 2. (817 aa)
	snrnp200	Small nuclear ribonucleoprotein 200 (U5). (2136 aa)

Your Current Organism:

Amphiprion ocellaris

NCBI taxonomy Id: 80972
Other names: A. ocellaris, clown anemonefish

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ddx23	eftud2	ENSAOCP00000012838	ENSAOCP00000031591	DEAD (Asp-Glu-Ala-Asp) box polypeptide 23.	Elongation factor Tu GTP binding domain containing 2.	0.997
ddx23	lsm2	ENSAOCP00000012838	ENSAOCP00000021866	DEAD (Asp-Glu-Ala-Asp) box polypeptide 23.	U6 snRNA-associated Sm-like protein LSm2; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	0.869
ddx23	lsm3	ENSAOCP00000012838	ENSAOCP00000004261	DEAD (Asp-Glu-Ala-Asp) box polypeptide 23.	U6 snRNA-associated Sm-like protein LSm3; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	0.728
ddx23	lsm4	ENSAOCP00000012838	ENSAOCP00000021542	DEAD (Asp-Glu-Ala-Asp) box polypeptide 23.	U6 snRNA-associated Sm-like protein LSm4; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	0.852
ddx23	lsm5	ENSAOCP00000012838	ENSAOCP00000017403	DEAD (Asp-Glu-Ala-Asp) box polypeptide 23.	U6 snRNA-associated Sm-like protein LSm5; Plays a role in U6 snRNP assembly and function. Binds to the 3' end of U6 snRNA.	0.850
ddx23	lsm6	ENSAOCP00000012838	ENSAOCP00000000258	DEAD (Asp-Glu-Ala-Asp) box polypeptide 23.	LSM6 homolog, U6 small nuclear RNA and mRNA degradation associated.	0.878
ddx23	lsm7	ENSAOCP00000012838	ENSAOCP00000011290	DEAD (Asp-Glu-Ala-Asp) box polypeptide 23.	LSM7 homolog, U6 small nuclear RNA and mRNA degradation associated.	0.893
ddx23	lsm8	ENSAOCP00000012838	ENSAOCP00000009751	DEAD (Asp-Glu-Ala-Asp) box polypeptide 23.	U6 snRNA-associated Sm-like protein LSm8; Plays role in pre-mRNA splicing as component of the U4/U6-U5 tri-snRNP complex that is involved in spliceosome assembly, and as component of the precatalytic spliceosome (spliceosome B complex). The heptameric LSM2-8 complex binds specifically to the 3'-terminal U-tract of U6 snRNA.	0.786
ddx23	prpf3	ENSAOCP00000012838	ENSAOCP00000007605	DEAD (Asp-Glu-Ala-Asp) box polypeptide 23.	PRP3 pre-mRNA processing factor 3 homolog (yeast).	0.972
ddx23	prpf31	ENSAOCP00000012838	ENSAOCP00000030366	DEAD (Asp-Glu-Ala-Asp) box polypeptide 23.	PRP31 pre-mRNA processing factor 31 homolog (yeast).	0.969
ddx23	prpf4	ENSAOCP00000012838	ENSAOCP00000021006	DEAD (Asp-Glu-Ala-Asp) box polypeptide 23.	PRP4 pre-mRNA processing factor 4 homolog (yeast).	0.954
ddx23	prpf6	ENSAOCP00000012838	ENSAOCP00000008883	DEAD (Asp-Glu-Ala-Asp) box polypeptide 23.	PRP6 pre-mRNA processing factor 6 homolog (S. cerevisiae).	0.998
ddx23	prpf8	ENSAOCP00000012838	ENSAOCP00000024074	DEAD (Asp-Glu-Ala-Asp) box polypeptide 23.	Pre-mRNA processing factor 8.	0.999
ddx23	sart1	ENSAOCP00000012838	ENSAOCP00000019471	DEAD (Asp-Glu-Ala-Asp) box polypeptide 23.	Spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP.	0.975
ddx23	sart3	ENSAOCP00000012838	ENSAOCP00000010830	DEAD (Asp-Glu-Ala-Asp) box polypeptide 23.	Spliceosome associated factor 3, U4/U6 recycling protein.	0.660
ddx23	snrnp200	ENSAOCP00000012838	ENSAOCP00000032305	DEAD (Asp-Glu-Ala-Asp) box polypeptide 23.	Small nuclear ribonucleoprotein 200 (U5).	0.996
ddx23	snrnp40	ENSAOCP00000012838	ENSAOCP00000020055	DEAD (Asp-Glu-Ala-Asp) box polypeptide 23.	Small nuclear ribonucleoprotein 40 (U5).	0.995
ddx23	txnl4a	ENSAOCP00000012838	ENSAOCP00000014875	DEAD (Asp-Glu-Ala-Asp) box polypeptide 23.	Thioredoxin-like protein; Plays role in pre-mRNA splicing. Belongs to the DIM1 family.	0.995
eftud2	ddx23	ENSAOCP00000031591	ENSAOCP00000012838	Elongation factor Tu GTP binding domain containing 2.	DEAD (Asp-Glu-Ala-Asp) box polypeptide 23.	0.997
eftud2	lsm2	ENSAOCP00000031591	ENSAOCP00000021866	Elongation factor Tu GTP binding domain containing 2.	U6 snRNA-associated Sm-like protein LSm2; Binds specifically to the 3'-terminal U-tract of U6 snRNA.	0.942