(101 nodes) Tyrosine-protein kinase, catalytic domain network (Amphiprion ocellaris)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC111588222	Tyrosine-protein kinase. (486 aa)
	LOC111574952	Macrophage stimulating 1 receptor a. (1376 aa)
	LOC111580186	Tyrosine-protein kinase. (607 aa)
	fes	Tyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (818 aa)
	LOC111565060	Eph receptor A6. (1049 aa)
	LOC111577204	Si:ch73-40a2.1. (914 aa)
	LOC111580728	Tyrosine-protein kinase. (511 aa)
	kdr	Kinase insert domain receptor (a type III receptor tyrosine kinase); Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1352 aa)
	kit	Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (983 aa)
	pdgfra	Platelet-derived growth factor receptor, alpha polypeptide; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1471 aa)
	tyk2	Tyrosine-protein kinase. (1171 aa)
	fer	Tyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily. (825 aa)
	CSK	Tyrosine-protein kinase. (451 aa)
	SRMS	Src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites; Belongs to the protein kinase superfamily. Tyr protein kinase family. (300 aa)
	egfr	Receptor protein-tyrosine kinase. (1194 aa)
	LOC111573731	Tyrosine-protein kinase. (1134 aa)
	LOC111578215	Kinase insert domain receptor like; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1312 aa)
	csf1r	Colony stimulating factor 1 receptor, a; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (980 aa)
	pdgfrb	Platelet-derived growth factor receptor, beta polypeptide; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1106 aa)
	LOC111571920	Tyrosine-protein kinase receptor. (1418 aa)
	ENSAOCP00000004497	TXK tyrosine kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. (244 aa)
	tec	Tyrosine-protein kinase. (654 aa)
	LOC111575382	Uncharacterized protein. (1031 aa)
	frk	Tyrosine-protein kinase. (517 aa)
	abl1	Tyrosine-protein kinase. (1121 aa)
	epha8	Uncharacterized protein. (986 aa)
	CSK-2	Tyrosine-protein kinase. (450 aa)
	ENSAOCP00000006553	Protein kinase domain-containing protein. (128 aa)
	epha4	Eph receptor A4, like. (964 aa)
	flt4	Fms-related tyrosine kinase 4; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1313 aa)
	LOC111564839	Tyrosine-protein kinase receptor. (798 aa)
	LOC111572455	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1226 aa)
	LOC111568257	Eph receptor B2b. (985 aa)
	LOC111571821	Receptor protein-tyrosine kinase. (1239 aa)
	LOC111586930	Protein kinase domain-containing protein. (317 aa)
	LOC111585552	Discoidin domain receptor family, member 2, like. (807 aa)
	fgfr2	Fibroblast growth factor receptor. (836 aa)
	LOC111579833	Protein tyrosine kinase 2ab; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1095 aa)
	epha3	Eph receptor A3. (994 aa)
	ntrk3	Tyrosine-protein kinase receptor. (815 aa)
	LOC111587416	Tyrosine-protein kinase receptor. (1413 aa)
	itk	Tyrosine-protein kinase. (595 aa)
	LOC111575718	Uncharacterized protein; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (981 aa)
	FYN	Tyrosine-protein kinase. (482 aa)
	LOC111563520	Discoidin domain receptor tyrosine kinase 2a. (850 aa)
	LOC111584754	Eph receptor A2 a. (974 aa)
	flt3	Fms-related tyrosine kinase 3; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (1016 aa)
	LOC111573260	Tyrosine-protein kinase. (537 aa)
	tyro3	TYRO3 protein tyrosine kinase. (879 aa)
	epha5	Uncharacterized protein. (971 aa)
	lck	Tyrosine-protein kinase. (500 aa)
	LOC111571538	Tyrosine-protein kinase. (1113 aa)
	LOC111567389	Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1143 aa)
	LOC111582670	Tyrosine-protein kinase receptor. (1501 aa)
	LOC111569056	Tyrosine-protein kinase receptor. (1288 aa)
	ephb4	Eph receptor B4a. (985 aa)
	ntrk1	Tyrosine-protein kinase receptor. (797 aa)
	LOC111577313	EPH receptor B1. (998 aa)
	LOC111586506	Uncharacterized protein. (950 aa)
	ptk2b	Protein tyrosine kinase 2 beta, b; Belongs to the protein kinase superfamily. Tyr protein kinase family. (991 aa)
	tie1	Tyrosine kinase with immunoglobulin-like and EGF-like domains 1. (1113 aa)
	abl2	Tyrosine-protein kinase. (1180 aa)
	tnk1	Tyrosine kinase, non-receptor, 1; Belongs to the protein kinase superfamily. Tyr protein kinase family. (764 aa)
	mertk	C-mer proto-oncogene tyrosine kinase a. (945 aa)
	LOC111576077	Eph receptor B2a. (956 aa)
	fgfr3	Fibroblast growth factor receptor. (812 aa)
	ret	Proto-oncogene tyrosine-protein kinase receptor Ret; Receptor tyrosine-protein kinase involved in numerous cellular mechanisms including cell proliferation, neuronal navigation, cell migration, and cell differentiation upon binding with glial cell derived neurotrophic factor family ligands. (1109 aa)
	LOC111565508	Uncharacterized protein. (1087 aa)
	jak1	Tyrosine-protein kinase. (1179 aa)
	LOC111565506	Eph receptor A4b. (984 aa)
	LOC111577732	Receptor protein-tyrosine kinase. (1297 aa)
	AXL	AXL receptor tyrosine kinase. (927 aa)
	jak3	Tyrosine-protein kinase. (1114 aa)
	ddr1	Discoidin domain receptor tyrosine kinase 1. (1001 aa)
	LOC111567751	Tyrosine-protein kinase. (533 aa)
	LOC111567104	Tyrosine-protein kinase. (473 aa)
	LOC111577019	Tyrosine-protein kinase. (550 aa)
	LOC111565072	Tyrosine-protein kinase. (545 aa)
	tnk2	Tyrosine kinase, non-receptor, 2b; Belongs to the protein kinase superfamily. Tyr protein kinase family. (1124 aa)
	LOC111564725	Eph receptor A2 b. (993 aa)
	LOC111584156	Eph receptor B4b. (953 aa)
	LOC111575719	Protein kinase domain-containing protein. (904 aa)
	LOC111571065	Fibroblast growth factor receptor. (833 aa)
	hck	Tyrosine-protein kinase. (503 aa)
	met	MET proto-oncogene, receptor tyrosine kinase. (1420 aa)
	LOC111574054	Receptor protein-tyrosine kinase. (1250 aa)
	LOC111585408	Eph receptor B3a. (926 aa)
	mst1r	Macrophage stimulating 1 receptor b. (1374 aa)
	btk	Tyrosine-protein kinase. (636 aa)
	epha7	Eph receptor A7. (992 aa)
	MUSK	Muscle associated receptor tyrosine kinase. (853 aa)
	LOC111567450	Uncharacterized protein. (1047 aa)
	LOC111569809	Mast/stem cell growth factor receptor; Belongs to the protein kinase superfamily. Tyr protein kinase family. CSF-1/PDGF receptor subfamily. (967 aa)
	LOC111568611	Fibroblast growth factor receptor 4. (945 aa)
	YES1	Tyrosine-protein kinase. (552 aa)
	LOC111568919	Receptor protein-tyrosine kinase. (1027 aa)
	ntrk2	Tyrosine-protein kinase receptor. (815 aa)
	syk	Tyrosine-protein kinase. (625 aa)
	insr	Tyrosine-protein kinase receptor. (1368 aa)
	LOC111566214	Tyrosine-protein kinase. (546 aa)
	ENSAOCP00000032405	Discoidin domain receptor tyrosine kinase 2b. (853 aa)

Your Current Organism:

Amphiprion ocellaris

NCBI taxonomy Id: 80972
Other names: A. ocellaris, clown anemonefish

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CSK	FYN	ENSAOCP00000002312	ENSAOCP00000012515	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.670
CSK	LOC111565072	ENSAOCP00000002312	ENSAOCP00000023603	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.716
CSK	LOC111566214	ENSAOCP00000002312	ENSAOCP00000031707	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.749
CSK	LOC111567104	ENSAOCP00000002312	ENSAOCP00000022956	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.665
CSK	LOC111567389	ENSAOCP00000002312	ENSAOCP00000017911	Tyrosine-protein kinase.	Protein tyrosine kinase 2; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.591
CSK	LOC111567751	ENSAOCP00000002312	ENSAOCP00000022904	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.668
CSK	LOC111571821	ENSAOCP00000002312	ENSAOCP00000008488	Tyrosine-protein kinase.	Receptor protein-tyrosine kinase.	0.525
CSK	LOC111573260	ENSAOCP00000002312	ENSAOCP00000014566	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.666
CSK	LOC111574054	ENSAOCP00000002312	ENSAOCP00000028327	Tyrosine-protein kinase.	Receptor protein-tyrosine kinase.	0.525
CSK	LOC111574952	ENSAOCP00000002312	ENSAOCP00000000063	Tyrosine-protein kinase.	Macrophage stimulating 1 receptor a.	0.596
CSK	LOC111577019	ENSAOCP00000002312	ENSAOCP00000023194	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.750
CSK	LOC111577732	ENSAOCP00000002312	ENSAOCP00000021158	Tyrosine-protein kinase.	Receptor protein-tyrosine kinase.	0.525
CSK	LOC111579833	ENSAOCP00000002312	ENSAOCP00000009559	Tyrosine-protein kinase.	Protein tyrosine kinase 2ab; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.591
CSK	LOC111580186	ENSAOCP00000002312	ENSAOCP00000000221	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.486
CSK	LOC111580728	ENSAOCP00000002312	ENSAOCP00000001949	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.716
CSK	LOC111588222	ENSAOCP00000002312	ENSAOCP00000023360	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.715
CSK	SRMS	ENSAOCP00000002312	ENSAOCP00000002717	Tyrosine-protein kinase.	Src-related kinase lacking C-terminal regulatory tyrosine and N-terminal myristylation sites; Belongs to the protein kinase superfamily. Tyr protein kinase family.	0.661
CSK	YES1	ENSAOCP00000002312	ENSAOCP00000031212	Tyrosine-protein kinase.	Tyrosine-protein kinase.	0.715
CSK	egfr	ENSAOCP00000002312	ENSAOCP00000003053	Tyrosine-protein kinase.	Receptor protein-tyrosine kinase.	0.525
CSK	fer	ENSAOCP00000002312	ENSAOCP00000002310	Tyrosine-protein kinase.	Tyrosine-protein kinase; Belongs to the protein kinase superfamily. Tyr protein kinase family. Fes/fps subfamily.	0.463