(10 nodes) Ribosome localization, and PA2G4 family network (Oreochromis niloticus)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

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second shell of interactors

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proteins of unknown 3D structure

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Known Interactions

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Predicted Interactions

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protein homology

Your Input:
	Mdn1	Midasin; Nuclear chaperone required for maturation and nuclear export of pre-60S ribosome subunits; Belongs to the midasin family. (5480 aa)
	Lsg1	Large 60S subunit nuclear export GTPase 1. (642 aa)
	znf593	Zinc finger protein 593. (129 aa)
	LOC100711208	Proliferation-associated 2G4, b. (392 aa)
	znf622	Zinc finger protein 622. (472 aa)
	eif6	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis. (246 aa)
	nmd3	60S ribosomal export protein NMD3; Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit; Belongs to the NMD3 family. (505 aa)
	sdad1	Protein SDA1; Required for 60S pre-ribosomal subunits export to the cytoplasm; Belongs to the SDA1 family. (707 aa)
	pa2g4	Proliferation-associated 2G4, a. (391 aa)
	nle1	Notchless homolog 1 (Drosophila). (486 aa)

Your Current Organism:

Oreochromis niloticus

NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC100711208	Lsg1	ENSONIP00000015309	ENSONIP00000003300	Proliferation-associated 2G4, b.	Large 60S subunit nuclear export GTPase 1.	0.938
LOC100711208	Mdn1	ENSONIP00000015309	ENSONIP00000002021	Proliferation-associated 2G4, b.	Midasin; Nuclear chaperone required for maturation and nuclear export of pre-60S ribosome subunits; Belongs to the midasin family.	0.724
LOC100711208	eif6	ENSONIP00000015309	ENSONIP00000023371	Proliferation-associated 2G4, b.	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis.	0.924
LOC100711208	nle1	ENSONIP00000015309	ENSONIP00000081516	Proliferation-associated 2G4, b.	Notchless homolog 1 (Drosophila).	0.949
LOC100711208	nmd3	ENSONIP00000015309	ENSONIP00000028531	Proliferation-associated 2G4, b.	60S ribosomal export protein NMD3; Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit; Belongs to the NMD3 family.	0.965
LOC100711208	sdad1	ENSONIP00000015309	ENSONIP00000047123	Proliferation-associated 2G4, b.	Protein SDA1; Required for 60S pre-ribosomal subunits export to the cytoplasm; Belongs to the SDA1 family.	0.947
LOC100711208	znf593	ENSONIP00000015309	ENSONIP00000004494	Proliferation-associated 2G4, b.	Zinc finger protein 593.	0.917
LOC100711208	znf622	ENSONIP00000015309	ENSONIP00000015631	Proliferation-associated 2G4, b.	Zinc finger protein 622.	0.844
Lsg1	LOC100711208	ENSONIP00000003300	ENSONIP00000015309	Large 60S subunit nuclear export GTPase 1.	Proliferation-associated 2G4, b.	0.938
Lsg1	Mdn1	ENSONIP00000003300	ENSONIP00000002021	Large 60S subunit nuclear export GTPase 1.	Midasin; Nuclear chaperone required for maturation and nuclear export of pre-60S ribosome subunits; Belongs to the midasin family.	0.651
Lsg1	eif6	ENSONIP00000003300	ENSONIP00000023371	Large 60S subunit nuclear export GTPase 1.	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis.	0.984
Lsg1	nle1	ENSONIP00000003300	ENSONIP00000081516	Large 60S subunit nuclear export GTPase 1.	Notchless homolog 1 (Drosophila).	0.777
Lsg1	nmd3	ENSONIP00000003300	ENSONIP00000028531	Large 60S subunit nuclear export GTPase 1.	60S ribosomal export protein NMD3; Acts as an adapter for the XPO1/CRM1-mediated export of the 60S ribosomal subunit; Belongs to the NMD3 family.	0.995
Lsg1	pa2g4	ENSONIP00000003300	ENSONIP00000077766	Large 60S subunit nuclear export GTPase 1.	Proliferation-associated 2G4, a.	0.938
Lsg1	sdad1	ENSONIP00000003300	ENSONIP00000047123	Large 60S subunit nuclear export GTPase 1.	Protein SDA1; Required for 60S pre-ribosomal subunits export to the cytoplasm; Belongs to the SDA1 family.	0.976
Lsg1	znf593	ENSONIP00000003300	ENSONIP00000004494	Large 60S subunit nuclear export GTPase 1.	Zinc finger protein 593.	0.881
Lsg1	znf622	ENSONIP00000003300	ENSONIP00000015631	Large 60S subunit nuclear export GTPase 1.	Zinc finger protein 622.	0.940
Mdn1	LOC100711208	ENSONIP00000002021	ENSONIP00000015309	Midasin; Nuclear chaperone required for maturation and nuclear export of pre-60S ribosome subunits; Belongs to the midasin family.	Proliferation-associated 2G4, b.	0.724
Mdn1	Lsg1	ENSONIP00000002021	ENSONIP00000003300	Midasin; Nuclear chaperone required for maturation and nuclear export of pre-60S ribosome subunits; Belongs to the midasin family.	Large 60S subunit nuclear export GTPase 1.	0.651
Mdn1	eif6	ENSONIP00000002021	ENSONIP00000023371	Midasin; Nuclear chaperone required for maturation and nuclear export of pre-60S ribosome subunits; Belongs to the midasin family.	Eukaryotic translation initiation factor 6; Binds to the 60S ribosomal subunit and prevents its association with the 40S ribosomal subunit to form the 80S initiation complex in the cytoplasm. May also be involved in ribosome biogenesis.	0.695