(45 nodes) Mixed, incl. Prp19 complex, and Catalytic step 2 spliceosome network (Oreochromis niloticus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	I3IUQ0_ORENI	ISY1 splicing factor homolog. (250 aa)
	snw1	SNW domain containing 1. (536 aa)
	yju2	YJU2 splicing factor homolog. (344 aa)
	LOC100702978	Src homology 2 domain containing transforming protein D, a. (406 aa)
	dhx16	DEAH (Asp-Glu-Ala-His) box polypeptide 16. (1055 aa)
	ccdc12	Coiled-coil domain containing 12. (163 aa)
	cwc25	CWC25 spliceosome associated protein homolog. (403 aa)
	WDR25	WD repeat domain 25. (503 aa)
	bud13	BUD13 homolog. (596 aa)
	srrm1	Serine/arginine repetitive matrix 1. (867 aa)
	ctnnbl1	Catenin, beta like 1. (577 aa)
	bcas2	BCAS2 pre-mRNA processing factor. (225 aa)
	SRRM3	Serine/arginine repetitive matrix protein 3 isoform X1. (647 aa)
	rbm22	RNA binding motif protein 22. (427 aa)
	cdc40	Cell division cycle 40 homolog (S. cerevisiae). (581 aa)
	WDR70	WD repeat domain 70. (651 aa)
	ppil1	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (202 aa)
	cwc27	CWC27 spliceosome associated cyclophilin. (482 aa)
	SNIP1	Smad nuclear interacting protein 1. (376 aa)
	gpkow	G patch domain and KOW motifs. (559 aa)
	parpbp	PARP1 binding protein. (610 aa)
	dhx8	DEAH (Asp-Glu-Ala-His) box polypeptide 8. (1213 aa)
	slu7	SLU7 homolog, splicing factor. (570 aa)
	ppwd1	Peptidylprolyl isomerase domain and WD repeat containing 1. (643 aa)
	ENSONIP00000038061	annotation not available (358 aa)
	ppil3	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (167 aa)
	prpf19	Pre-mRNA processing factor 19. (1489 aa)
	xab2	XPA binding protein 2. (854 aa)
	rbmx2	RRM domain-containing protein. (71 aa)
	dhx38	DEAH (Asp-Glu-Ala-His) box polypeptide 38. (1261 aa)
	ENSONIP00000052157	annotation not available (201 aa)
	cwc15	CWC15 spliceosome associated protein homolog. (237 aa)
	plrg1	Pleiotropic regulator 1. (513 aa)
	LOC100706680	Peroxisome proliferator-activated receptor gamma coactivator-related protein 1 isoform X1. (1167 aa)
	prpf18	PRP18 pre-mRNA processing factor 18 homolog (yeast). (350 aa)
	I3JSM1_ORENI	Serine/arginine repetitive matrix 2. (1331 aa)
	crnkl1	Crooked neck pre-mRNA splicing factor 1. (758 aa)
	dhx35	DEAH-box helicase 35. (706 aa)
	dhx33	DEAH (Asp-Glu-Ala-His) box polypeptide 33. (681 aa)
	ENSONIP00000076847	Cell division cycle 5-like protein. (335 aa)
	syf2	SYF2 pre-mRNA-splicing factor. (239 aa)
	bud31	BUD31 homolog. (144 aa)
	cdc5l	CDC5 cell division cycle 5-like (S. pombe). (882 aa)
	rnf113a	Ring finger protein 113A. (322 aa)
	ppil2	Peptidylprolyl isomerase (cyclophilin)-like 2. (538 aa)

Your Current Organism:

Oreochromis niloticus

NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSONIP00000038061	ENSONIP00000052157	ENSONIP00000038061	ENSONIP00000052157	annotation not available	annotation not available	0.761
ENSONIP00000038061	I3IUQ0_ORENI	ENSONIP00000038061	ENSONIP00000000341	annotation not available	ISY1 splicing factor homolog.	0.900
ENSONIP00000038061	I3JSM1_ORENI	ENSONIP00000038061	ENSONIP00000072810	annotation not available	Serine/arginine repetitive matrix 2.	0.798
ENSONIP00000038061	LOC100702978	ENSONIP00000038061	ENSONIP00000001437	annotation not available	Src homology 2 domain containing transforming protein D, a.	0.785
ENSONIP00000038061	LOC100706680	ENSONIP00000038061	ENSONIP00000068013	annotation not available	Peroxisome proliferator-activated receptor gamma coactivator-related protein 1 isoform X1.	0.637
ENSONIP00000038061	SNIP1	ENSONIP00000038061	ENSONIP00000020508	annotation not available	Smad nuclear interacting protein 1.	0.831
ENSONIP00000038061	SRRM3	ENSONIP00000038061	ENSONIP00000016023	annotation not available	Serine/arginine repetitive matrix protein 3 isoform X1.	0.798
ENSONIP00000038061	WDR25	ENSONIP00000038061	ENSONIP00000004471	annotation not available	WD repeat domain 25.	0.805
ENSONIP00000038061	WDR70	ENSONIP00000038061	ENSONIP00000017600	annotation not available	WD repeat domain 70.	0.541
ENSONIP00000038061	bcas2	ENSONIP00000038061	ENSONIP00000011614	annotation not available	BCAS2 pre-mRNA processing factor.	0.961
ENSONIP00000038061	bud13	ENSONIP00000038061	ENSONIP00000006178	annotation not available	BUD13 homolog.	0.898
ENSONIP00000038061	bud31	ENSONIP00000038061	ENSONIP00000078046	annotation not available	BUD31 homolog.	0.898
ENSONIP00000038061	ccdc12	ENSONIP00000038061	ENSONIP00000003832	annotation not available	Coiled-coil domain containing 12.	0.829
ENSONIP00000038061	cdc40	ENSONIP00000038061	ENSONIP00000016887	annotation not available	Cell division cycle 40 homolog (S. cerevisiae).	0.913
ENSONIP00000038061	crnkl1	ENSONIP00000038061	ENSONIP00000072834	annotation not available	Crooked neck pre-mRNA splicing factor 1.	0.930
ENSONIP00000038061	ctnnbl1	ENSONIP00000038061	ENSONIP00000011589	annotation not available	Catenin, beta like 1.	0.951
ENSONIP00000038061	cwc15	ENSONIP00000038061	ENSONIP00000064198	annotation not available	CWC15 spliceosome associated protein homolog.	0.961
ENSONIP00000038061	cwc25	ENSONIP00000038061	ENSONIP00000004083	annotation not available	CWC25 spliceosome associated protein homolog.	0.899
ENSONIP00000038061	cwc27	ENSONIP00000038061	ENSONIP00000019396	annotation not available	CWC27 spliceosome associated cyclophilin.	0.891
ENSONIP00000038061	dhx16	ENSONIP00000038061	ENSONIP00000002785	annotation not available	DEAH (Asp-Glu-Ala-His) box polypeptide 16.	0.888