STRINGSTRING
I3ITT0_ORENI I3ITT0_ORENI GOT1 GOT1 pdhb pdhb ACLY ACLY rbm45 rbm45 pgls pgls parp6 parp6 LOC100692119 LOC100692119 I3J820_ORENI I3J820_ORENI bckdha bckdha h6pd h6pd pck1 pck1 LOC102082909 LOC102082909 sdha sdha Nit2 Nit2 pdha1 pdha1 LOC100698934 LOC100698934 LOC100694281 LOC100694281 I3JQY5_ORENI I3JQY5_ORENI eno4 eno4 dld dld LOC100705870 LOC100705870 ogdh ogdh idh3g idh3g mdh1b mdh1b rpia rpia LOC100703707 LOC100703707 gpt gpt pdhx pdhx LOC100712280 LOC100712280 txnrd2 txnrd2 LOC100692108 LOC100692108 mycbpap mycbpap pgk1 pgk1 prps1 prps1 I3KPD3_ORENI I3KPD3_ORENI got1 got1 LOC100692737 LOC100692737 LOC102082087 LOC102082087 LOC100710799 LOC100710799 ald ald I3KWE4_ORENI I3KWE4_ORENI mdh2 mdh2 fh fh I3KCF1_ORENI I3KCF1_ORENI LOC109194175 LOC109194175 pck2 pck2 Idh1 Idh1 bpgm bpgm aco2 aco2 pdk3 pdk3 me1 me1 dhtkd1 dhtkd1 I3KIC5_ORENI I3KIC5_ORENI LOC100691863 LOC100691863 pfkfb3 pfkfb3 LOC100694159 LOC100694159 gapdh gapdh LOC100704344 LOC100704344 LOC100710146 LOC100710146 ENSONIP00000034513 ENSONIP00000034513 LOC100703776 LOC100703776 TKT TKT idh3b idh3b ENSONIP00000037117 ENSONIP00000037117 I3KS66_ORENI I3KS66_ORENI LOC100707813 LOC100707813 LOC100701127 LOC100701127 LOC100700674 LOC100700674 pfk pfk ldhd ldhd PC PC LOC100690242 LOC100690242 pdp1 pdp1 me2 me2 ENSONIP00000041052 ENSONIP00000041052 LOC100711978 LOC100711978 LOC100534543 LOC100534543 LOC100699677 LOC100699677 LOC100705311 LOC100705311 dlat dlat ENSONIP00000042650 ENSONIP00000042650 LOC100702997 LOC100702997 LOC100703946 LOC100703946 LOC100709338 LOC100709338 DLST DLST pfkl pfkl HK1 HK1 ENSONIP00000047436 ENSONIP00000047436 LOC100707874 LOC100707874 ENSONIP00000050201 ENSONIP00000050201 LOC100694503 LOC100694503 LOC100712084 LOC100712084 Ogdhl Ogdhl LOC100702976 LOC100702976 LOC100706997 LOC100706997 I3JQ69_ORENI I3JQ69_ORENI sdhc sdhc TK TK LOC100696823 LOC100696823 rbks rbks pgam1 pgam1 ddo ddo taldo1 taldo1 suclg2 suclg2 cs cs dbt dbt I3JTA4_ORENI I3JTA4_ORENI I3JH18_ORENI I3JH18_ORENI tpi tpi bckdhb bckdhb LOC100703249 LOC100703249 pdk1 pdk1 eno1 eno1 G6pdh G6pdh I3K606_ORENI I3K606_ORENI LOC100700435 LOC100700435 OGDH OGDH LOC100696295 LOC100696295 LOC100702375 LOC100702375 pkm pkm LOC100702682 LOC100702682 ENO2 ENO2 sucla2 sucla2 ENSONIP00000071978 ENSONIP00000071978 LOC100534427 LOC100534427 me3 me3 bckdk bckdk LOC100711262 LOC100711262 LOC100691871 LOC100691871 gapdhs gapdhs suclg1 suclg1 SDHB SDHB LOC100696029 LOC100696029 LOC100702713 LOC100702713 LOC100711605 LOC100711605
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query proteins and first shell of interactors
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second shell of interactors
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proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
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Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
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textmining
co-expression
protein homology
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I3ITT0_ORENITP53 induced glycolysis regulatory phosphatase b. (318 aa)
GOT1Aspartate aminotransferase. (410 aa)
pdhbPyruvate dehydrogenase E1 component subunit beta; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO2. (360 aa)
ACLYATP-citrate synthase; In the C-terminal section; belongs to the succinate/malate CoA ligase alpha subunit family. (1107 aa)
rbm45RNA binding motif protein 45. (521 aa)
pgls6-phosphogluconolactonase; Hydrolysis of 6-phosphogluconolactone to 6-phosphogluconate. (253 aa)
parp6Poly [ADP-ribose] polymerase. (642 aa)
LOC100692119Isocitrate dehydrogenase [NAD] subunit, mitochondrial. (367 aa)
I3J820_ORENIPhosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (264 aa)
bckdha2-oxoisovalerate dehydrogenase subunit alpha; The branched-chain alpha-keto dehydrogenase complex catalyzes the overall conversion of alpha-keto acids to acyl-CoA and CO(2). It contains multiple copies of three enzymatic components: branched-chain alpha-keto acid decarboxylase (E1), lipoamide acyltransferase (E2) and lipoamide dehydrogenase (E3). (446 aa)
h6pdHexose-6-phosphate dehydrogenase (glucose 1-dehydrogenase). (791 aa)
pck1Phosphoenolpyruvate carboxykinase 1 (soluble). (672 aa)
LOC102082909Si:ch211-114c12.2. (627 aa)
sdhaSuccinate dehydrogenase [ubiquinone] flavoprotein subunit, mitochondrial; Flavoprotein (FP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (663 aa)
Nit2Nitrilase family, member 2. (285 aa)
pdha1Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (393 aa)
LOC100698934Poly [ADP-ribose] polymerase. (594 aa)
LOC100694281L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (352 aa)
I3JQY5_ORENIFamily with sequence similarity 114 member A1. (533 aa)
eno4Enolase 4. (568 aa)
dldDihydrolipoyl dehydrogenase. (508 aa)
LOC100705870Fructose-bisphosphatase 1; Belongs to the FBPase class 1 family. (339 aa)
ogdhOxoglutarate (alpha-ketoglutarate) dehydrogenase b (lipoamide). (959 aa)
idh3gIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (392 aa)
mdh1bMalate dehydrogenase 1B, NAD (soluble). (465 aa)
rpiaRibose 5-phosphate isomerase A (ribose 5-phosphate epimerase). (287 aa)
LOC100703707Fructose-1,6-bisphosphatase 1a; Belongs to the FBPase class 1 family. (709 aa)
gptSi:ch211-217a12.1. (994 aa)
pdhxDihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (493 aa)
LOC1007122806PF2K domain-containing protein. (536 aa)
txnrd2Thioredoxin reductase 2, tandem duplicate 1. (512 aa)
LOC100692108Ribulose-phosphate 3-epimerase; Belongs to the ribulose-phosphate 3-epimerase family. (228 aa)
mycbpapMycbp associated protein. (745 aa)
pgk1Phosphoglycerate kinase. (417 aa)
prps1Phosphoribosyl pyrophosphate synthetase 1B. (386 aa)
I3KPD3_ORENIGlucose-6-phosphate isomerase; Belongs to the GPI family. (552 aa)
got1Aspartate aminotransferase. (414 aa)
LOC100692737Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (254 aa)
LOC102082087Aminotran_1_2 domain-containing protein. (468 aa)
LOC100710799Aminotran_1_2 domain-containing protein. (435 aa)
aldFructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (363 aa)
I3KWE4_ORENIDihydrolipoamide S-succinyltransferase. (480 aa)
mdh2Malate dehydrogenase. (331 aa)
fhFumarate hydratase. (499 aa)
I3KCF1_ORENIATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (777 aa)
LOC109194175Succinate dehydrogenase [ubiquinone] cytochrome b small subunit; Membrane-anchoring subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q); Belongs to the CybS family. (164 aa)
pck2Phosphoenolpyruvate carboxykinase 2 (mitochondrial). (641 aa)
Idh1Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (429 aa)
bpgmPhosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (258 aa)
aco2Aconitate hydratase, mitochondrial; Belongs to the aconitase/IPM isomerase family. (833 aa)
pdk3Protein-serine/threonine kinase. (434 aa)
me1Malic enzyme. (588 aa)
dhtkd1Dehydrogenase E1 and transketolase domain containing 1. (926 aa)
I3KIC5_ORENIIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (436 aa)
LOC100691863Transketolase a. (649 aa)
pfkfb36-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3. (534 aa)
LOC100694159Hexokinase 2. (937 aa)
gapdhGlyceraldehyde-3-phosphate dehydrogenase. (359 aa)
LOC100704344Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (422 aa)
LOC100710146TP53 induced glycolysis regulatory phosphatase a. (271 aa)
ENSONIP00000034513annotation not available (780 aa)
LOC1007037766PF2K domain-containing protein. (546 aa)
TKTTransketolase. (632 aa)
idh3bIsocitrate dehydrogenase [NAD] subunit, mitochondrial. (386 aa)
ENSONIP00000037117annotation not available (441 aa)
I3KS66_ORENI6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4b. (532 aa)
LOC100707813Phosphoribosyl pyrophosphate synthetase-associated protein 2. (370 aa)
LOC100701127Glutaryl-CoA dehydrogenase a. (443 aa)
LOC100700674Phosphoribosyl pyrophosphate synthetase associated protein 1. (390 aa)
pfkATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (797 aa)
ldhdLactate dehydrogenase D. (496 aa)
PCPyruvate carboxylase; Catalyzes a 2-step reaction, involving the ATP-dependent carboxylation of the covalently attached biotin in the first step and the transfer of the carboxyl group to pyruvate in the second. (1209 aa)
LOC100690242Glutamic pyruvate transaminase (alanine aminotransferase) 2, like. (560 aa)
pdp1Pyruvate dehyrogenase phosphatase catalytic subunit 1. (541 aa)
me2Malic enzyme. (591 aa)
ENSONIP00000041052Succinate dehydrogenase [ubiquinone] cytochrome b small subunit B, mitochondrial-like. (148 aa)
LOC100711978Malate dehydrogenase. (383 aa)
LOC100534543Pyruvate kinase; Belongs to the pyruvate kinase family. (543 aa)
LOC100699677Enolase 3, (beta, muscle). (464 aa)
LOC100705311Aspartate aminotransferase. (449 aa)
dlatAcetyltransferase component of pyruvate dehydrogenase complex; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (638 aa)
ENSONIP00000042650annotation not available (337 aa)
LOC100702997ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (784 aa)
LOC100703946Glucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. (560 aa)
LOC100709338Pyruvate dehydrogenase E1 component subunit alpha; The pyruvate dehydrogenase complex catalyzes the overall conversion of pyruvate to acetyl-CoA and CO(2). (395 aa)
DLSTDihydrolipoamide S-succinyltransferase. (448 aa)
pfklATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (799 aa)
HK1Hexokinase 1. (970 aa)
ENSONIP00000047436Ribose-phosphate pyrophosphokinase 2. (342 aa)
LOC100707874Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (456 aa)
ENSONIP00000050201Enolase 1b, (alpha). (471 aa)
LOC100694503Fructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (419 aa)
LOC100712084Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (351 aa)
OgdhlOxoglutarate dehydrogenase like. (1019 aa)
LOC100702976Thioredoxin reductase 3. (602 aa)
LOC100706997ATP-citrate synthase; In the C-terminal section; belongs to the succinate/malate CoA ligase alpha subunit family. (1150 aa)
I3JQ69_ORENIE1_dh domain-containing protein. (376 aa)
sdhcSuccinate dehydrogenase cytochrome b560 subunit, mitochondrial. (191 aa)
TKTransketolase b. (625 aa)
LOC100696823Glyceraldehyde-3-phosphate dehydrogenase. (361 aa)
rbksRibokinase; Catalyzes the phosphorylation of ribose at O-5 in a reaction requiring ATP and magnesium. The resulting D-ribose-5-phosphate can then be used either for sythesis of nucleotides, histidine, and tryptophan, or as a component of the pentose phosphate pathway. (329 aa)
pgam1Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (254 aa)
ddoZgc:172341. (339 aa)
taldo1Transaldolase; Transaldolase is important for the balance of metabolites in the pentose-phosphate pathway. (355 aa)
suclg2Succinate--CoA ligase [GDP-forming] subunit beta, mitochondrial; GTP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (431 aa)
csCitrate synthase; Belongs to the citrate synthase family. (481 aa)
dbtDihydrolipoamide acetyltransferase component of pyruvate dehydrogenase complex. (486 aa)
I3JTA4_ORENIAminotran_1_2 domain-containing protein. (490 aa)
I3JH18_ORENIPyruvate kinase; Belongs to the pyruvate kinase family. (575 aa)
tpiTriosephosphate isomerase. (247 aa)
bckdhbBranched chain keto acid dehydrogenase E1 subunit beta. (402 aa)
LOC1007032496-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4a. (530 aa)
pdk1Protein-serine/threonine kinase. (430 aa)
eno1Enolase 1a, (alpha). (451 aa)
G6pdhGlucose-6-phosphate 1-dehydrogenase; Catalyzes the rate-limiting step of the oxidative pentose- phosphate pathway, which represents a route for the dissimilation of carbohydrates besides glycolysis. (559 aa)
I3K606_ORENIFructose-bisphosphate aldolase; Belongs to the class I fructose-bisphosphate aldolase family. (405 aa)
LOC1007004356-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1. (527 aa)
OGDHOxoglutarate dehydrogenase. (1029 aa)
LOC100696295Enolase 2. (459 aa)
LOC100702375ATP-dependent 6-phosphofructokinase; Catalyzes the phosphorylation of D-fructose 6-phosphate to fructose 1,6-bisphosphate by ATP, the first committing step of glycolysis; Belongs to the phosphofructokinase type A (PFKA) family. ATP-dependent PFK group I subfamily. Eukaryotic two domain clade 'E' sub-subfamily. (794 aa)
pkmPyruvate kinase; Belongs to the pyruvate kinase family. (596 aa)
LOC100702682Isocitrate dehydrogenase [NADP]; Belongs to the isocitrate and isopropylmalate dehydrogenases family. (593 aa)
ENO2Enolase 2. (443 aa)
sucla2Succinate--CoA ligase [ADP-forming] subunit beta, mitochondrial; ATP-specific succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of ATP and thus represents the only step of substrate-level phosphorylation in the TCA. The beta subunit provides nucleotide specificity of the enzyme and binds the substrate succinate, while the binding sites for coenzyme A and phosphate are found in the alpha subunit. (466 aa)
ENSONIP00000071978annotation not available (168 aa)
LOC100534427L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (351 aa)
me3Malic enzyme. (628 aa)
bckdkProtein-serine/threonine kinase. (482 aa)
LOC100711262Malate dehydrogenase, cytoplasmic isoform X2. (364 aa)
LOC100691871Isocitrate dehydrogenase [NAD] subunit, mitochondrial. (394 aa)
gapdhsGlyceraldehyde-3-phosphate dehydrogenase. (375 aa)
suclg1Succinate--CoA ligase [ADP/GDP-forming] subunit alpha, mitochondrial; Succinyl-CoA synthetase functions in the citric acid cycle (TCA), coupling the hydrolysis of succinyl-CoA to the synthesis of either ATP or GTP and thus represents the only step of substrate-level phosphorylation in the TCA. The alpha subunit of the enzyme binds the substrates coenzyme A and phosphate, while succinate binding and specificity for either ATP or GTP is provided by different beta subunits. (360 aa)
SDHBSuccinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (282 aa)
LOC100696029Triosephosphate isomerase. (248 aa)
LOC100702713L-lactate dehydrogenase; Belongs to the LDH/MDH superfamily. (355 aa)
LOC100711605Malate synthase-like. (567 aa)
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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