(51 nodes) Starch and sucrose metabolism, and Amino sugar biosynthetic process network (Oreochromis niloticus)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC100711459	Glycogenin 1a. (382 aa)
	agl	Amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase b. (1536 aa)
	uap1	UDP-N-acetylglucosamine pyrophosphorylase 1. (524 aa)
	LOC100704840	Glucose-6-phosphate isomerase; Belongs to the GPI family. (553 aa)
	tmco3	Transmembrane and coiled-coil domains 3. (681 aa)
	LOC100695517	Si:ch73-12o23.1; Belongs to the glycosyl hydrolase 31 family. (976 aa)
	LOC100711198	Alpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (862 aa)
	gbe1	Glucan (1,4-alpha-), branching enzyme 1b. (730 aa)
	treh	Trehalase. (579 aa)
	ENSONIP00000009261	Glycogenin-1 isoform X1. (428 aa)
	LOC100709447	Glucosidase, beta, acid 3 (gene/pseudogene); Belongs to the glycosyl hydrolase 1 family. (467 aa)
	efcab7	EF-hand calcium binding domain 7. (620 aa)
	pgm2	Phosphoglucomutase 2. (611 aa)
	LOC100690674	Glutamine--fructose-6-phosphate transaminase 1. (716 aa)
	gckr	Uncharacterized protein. (580 aa)
	pgm5	Phosphoglucomutase 5; Belongs to the phosphohexose mutase family. (580 aa)
	Pgghg	Protein-glucosylgalactosylhydroxylysine glucosidase. (696 aa)
	alkbh3	AlkB homolog 3, alpha-ketoglutarate-dependent dioxygenase. (296 aa)
	LOC100710204	UTP--glucose-1-phosphate uridylyltransferase. (501 aa)
	I3KL20_ORENI	Phosphotransferase. (414 aa)
	LOC100690676	Phosphotransferase. (446 aa)
	ENSONIP00000023323	annotation not available (429 aa)
	LOC100534494	Alpha-amylase. (518 aa)
	pgm2l1	Phosphoglucomutase 2-like 1. (655 aa)
	LOC100706889	Alpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (852 aa)
	LOC100696859	UDP-N-acetylglucosamine pyrophosphorylase 1, like 1. (501 aa)
	pygl	Alpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties. (869 aa)
	LOC109194289	Alpha-amylase. (511 aa)
	gys2	Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan. (709 aa)
	ENSONIP00000041967	annotation not available (236 aa)
	LOC102076176	Chitin synthase chs-1. (1432 aa)
	gaa	Glucosidase, alpha; acid (Pompe disease, glycogen storage disease type II); Belongs to the glycosyl hydrolase 31 family. (938 aa)
	gnpda2	Glucosamine-6-phosphate isomerase. (292 aa)
	pudp	Pseudouridine 5'-phosphatase. (298 aa)
	nagk	Meiosis 1 associated protein. (945 aa)
	gys1	Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan. (716 aa)
	LOC100694059	Glucosamine-6-phosphate isomerase. (276 aa)
	ENSONIP00000065311	annotation not available (249 aa)
	mpi	Mannose-6-phosphate isomerase. (422 aa)
	gnpnat1	Glucosamine 6-phosphate N-acetyltransferase. (206 aa)
	pgm3	Phosphoacetylglucosamine mutase; Catalyzes the conversion of GlcNAc-6-P into GlcNAc-1-P during the synthesis of uridine diphosphate/UDP-GlcNAc, a sugar nucleotide critical to multiple glycosylation pathways including protein N- and O- glycosylation; Belongs to the phosphohexose mutase family. (546 aa)
	LOC102076559	Chitin synthase chs-2. (1282 aa)
	ENSONIP00000073026	Glucosamine-6-phosphate isomerase 1. (208 aa)
	ugp2	UTP--glucose-1-phosphate uridylyltransferase. (517 aa)
	ENSONIP00000074803	Amidohydrolase domain containing 2. (431 aa)
	ENSONIP00000075688	annotation not available (203 aa)
	I3KK26_ORENI	Hexokinase domain containing 1. (1074 aa)
	LOC109199111	N-acetylglucosamine-6-phosphate deacetylase; Belongs to the metallo-dependent hydrolases superfamily. NagA family. (424 aa)
	I3KQP7_ORENI	Uncharacterized protein. (598 aa)
	yipf6	Protein YIPF. (226 aa)
	LOC100692652	Glutamine-fructose-6-phosphate transaminase 2. (696 aa)

Your Current Organism:

Oreochromis niloticus

NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSONIP00000009261	LOC100695517	ENSONIP00000009261	ENSONIP00000004849	Glycogenin-1 isoform X1.	Si:ch73-12o23.1; Belongs to the glycosyl hydrolase 31 family.	0.466
ENSONIP00000009261	LOC100706889	ENSONIP00000009261	ENSONIP00000031970	Glycogenin-1 isoform X1.	Alpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.	0.679
ENSONIP00000009261	LOC100710204	ENSONIP00000009261	ENSONIP00000020155	Glycogenin-1 isoform X1.	UTP--glucose-1-phosphate uridylyltransferase.	0.931
ENSONIP00000009261	LOC100711198	ENSONIP00000009261	ENSONIP00000006270	Glycogenin-1 isoform X1.	Alpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.	0.679
ENSONIP00000009261	LOC100711459	ENSONIP00000009261	ENSONIP00000000944	Glycogenin-1 isoform X1.	Glycogenin 1a.	0.904
ENSONIP00000009261	agl	ENSONIP00000009261	ENSONIP00000002076	Glycogenin-1 isoform X1.	Amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase b.	0.842
ENSONIP00000009261	gaa	ENSONIP00000009261	ENSONIP00000047782	Glycogenin-1 isoform X1.	Glucosidase, alpha; acid (Pompe disease, glycogen storage disease type II); Belongs to the glycosyl hydrolase 31 family.	0.466
ENSONIP00000009261	gbe1	ENSONIP00000009261	ENSONIP00000007111	Glycogenin-1 isoform X1.	Glucan (1,4-alpha-), branching enzyme 1b.	0.990
ENSONIP00000009261	gys1	ENSONIP00000009261	ENSONIP00000056500	Glycogenin-1 isoform X1.	Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan.	0.993
ENSONIP00000009261	gys2	ENSONIP00000009261	ENSONIP00000040518	Glycogenin-1 isoform X1.	Glycogen [starch] synthase; Transfers the glycosyl residue from UDP-Glc to the non- reducing end of alpha-1,4-glucan.	0.995
ENSONIP00000009261	pygl	ENSONIP00000009261	ENSONIP00000038358	Glycogenin-1 isoform X1.	Alpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.	0.679
ENSONIP00000009261	ugp2	ENSONIP00000009261	ENSONIP00000073645	Glycogenin-1 isoform X1.	UTP--glucose-1-phosphate uridylyltransferase.	0.931
ENSONIP00000023323	I3KQP7_ORENI	ENSONIP00000023323	ENSONIP00000081332	annotation not available	Uncharacterized protein.	0.452
ENSONIP00000023323	LOC100706889	ENSONIP00000023323	ENSONIP00000031970	annotation not available	Alpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.	0.573
ENSONIP00000023323	LOC100711198	ENSONIP00000023323	ENSONIP00000006270	annotation not available	Alpha-1,4 glucan phosphorylase; Phosphorylase is an important allosteric enzyme in carbohydrate metabolism. Enzymes from different sources differ in their regulatory mechanisms and in their natural substrates. However, all known phosphorylases share catalytic and structural properties.	0.573
ENSONIP00000023323	Pgghg	ENSONIP00000023323	ENSONIP00000019593	annotation not available	Protein-glucosylgalactosylhydroxylysine glucosidase.	0.674
ENSONIP00000023323	agl	ENSONIP00000023323	ENSONIP00000002076	annotation not available	Amylo-alpha-1, 6-glucosidase, 4-alpha-glucanotransferase b.	0.454
ENSONIP00000023323	efcab7	ENSONIP00000023323	ENSONIP00000011090	annotation not available	EF-hand calcium binding domain 7.	0.452
ENSONIP00000023323	gbe1	ENSONIP00000023323	ENSONIP00000007111	annotation not available	Glucan (1,4-alpha-), branching enzyme 1b.	0.746
ENSONIP00000023323	pgm2	ENSONIP00000023323	ENSONIP00000011259	annotation not available	Phosphoglucomutase 2.	0.448