(10 nodes) MyD88-dependent toll-like receptor signaling pathway, and interleukin-1-mediated signaling pathway network (Oreochromis niloticus)

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Your Input:
	tirap	Toll-interleukin 1 receptor (TIR) domain containing adaptor protein. (291 aa)
	myd88	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response. (288 aa)
	LOC102076024	TIR domain-containing protein; Belongs to the Toll-like receptor family. (827 aa)
	TLR2	Uncharacterized protein. (787 aa)
	TLR2-2	Toll-like receptor 2 isoform X1. (786 aa)
	tollip	Toll interacting protein. (275 aa)
	TLR2-3	Toll-like receptor 2. (670 aa)
	traf6	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family. (616 aa)
	irak4	Interleukin-1 receptor-associated kinase 4. (463 aa)
	irak1	Interleukin-1 receptor-associated kinase 1. (752 aa)

Your Current Organism:

Oreochromis niloticus

NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC102076024	TLR2	ENSONIP00000017788	ENSONIP00000025925	TIR domain-containing protein; Belongs to the Toll-like receptor family.	Uncharacterized protein.	0.900
LOC102076024	TLR2-2	ENSONIP00000017788	ENSONIP00000029726	TIR domain-containing protein; Belongs to the Toll-like receptor family.	Toll-like receptor 2 isoform X1.	0.900
LOC102076024	TLR2-3	ENSONIP00000017788	ENSONIP00000054439	TIR domain-containing protein; Belongs to the Toll-like receptor family.	Toll-like receptor 2.	0.900
LOC102076024	myd88	ENSONIP00000017788	ENSONIP00000007350	TIR domain-containing protein; Belongs to the Toll-like receptor family.	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	0.939
LOC102076024	tirap	ENSONIP00000017788	ENSONIP00000006704	TIR domain-containing protein; Belongs to the Toll-like receptor family.	Toll-interleukin 1 receptor (TIR) domain containing adaptor protein.	0.933
TLR2	LOC102076024	ENSONIP00000025925	ENSONIP00000017788	Uncharacterized protein.	TIR domain-containing protein; Belongs to the Toll-like receptor family.	0.900
TLR2	irak1	ENSONIP00000025925	ENSONIP00000070688	Uncharacterized protein.	Interleukin-1 receptor-associated kinase 1.	0.522
TLR2	irak4	ENSONIP00000025925	ENSONIP00000065648	Uncharacterized protein.	Interleukin-1 receptor-associated kinase 4.	0.572
TLR2	myd88	ENSONIP00000025925	ENSONIP00000007350	Uncharacterized protein.	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	0.980
TLR2	tirap	ENSONIP00000025925	ENSONIP00000006704	Uncharacterized protein.	Toll-interleukin 1 receptor (TIR) domain containing adaptor protein.	0.942
TLR2	tollip	ENSONIP00000025925	ENSONIP00000045642	Uncharacterized protein.	Toll interacting protein.	0.920
TLR2	traf6	ENSONIP00000025925	ENSONIP00000057481	Uncharacterized protein.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.653
TLR2-2	LOC102076024	ENSONIP00000029726	ENSONIP00000017788	Toll-like receptor 2 isoform X1.	TIR domain-containing protein; Belongs to the Toll-like receptor family.	0.900
TLR2-2	irak1	ENSONIP00000029726	ENSONIP00000070688	Toll-like receptor 2 isoform X1.	Interleukin-1 receptor-associated kinase 1.	0.522
TLR2-2	irak4	ENSONIP00000029726	ENSONIP00000065648	Toll-like receptor 2 isoform X1.	Interleukin-1 receptor-associated kinase 4.	0.533
TLR2-2	myd88	ENSONIP00000029726	ENSONIP00000007350	Toll-like receptor 2 isoform X1.	Myeloid differentiation primary response protein MyD88; Adapter protein involved in the Toll-like receptor and IL-1 receptor signaling pathway in the innate immune response.	0.980
TLR2-2	tirap	ENSONIP00000029726	ENSONIP00000006704	Toll-like receptor 2 isoform X1.	Toll-interleukin 1 receptor (TIR) domain containing adaptor protein.	0.947
TLR2-2	tollip	ENSONIP00000029726	ENSONIP00000045642	Toll-like receptor 2 isoform X1.	Toll interacting protein.	0.920
TLR2-2	traf6	ENSONIP00000029726	ENSONIP00000057481	Toll-like receptor 2 isoform X1.	TNF receptor-associated factor; Belongs to the TNF receptor-associated factor family.	0.655
TLR2-3	LOC102076024	ENSONIP00000054439	ENSONIP00000017788	Toll-like receptor 2.	TIR domain-containing protein; Belongs to the Toll-like receptor family.	0.900