STRINGSTRING
aspn aspn ogn ogn bmp2 bmp2 ENSONIP00000001443 ENSONIP00000001443 LOC100711913 LOC100711913 LOC100695903 LOC100695903 bmp4 bmp4 tgfbi tgfbi I3J168_ORENI I3J168_ORENI bambi bambi LOC100700916 LOC100700916 LOC100711374 LOC100711374 bmp8a bmp8a LOC100690458 LOC100690458 LOC100694986 LOC100694986 I3JEN4_ORENI I3JEN4_ORENI LOC100694653 LOC100694653 smad7 smad7 acvr1 acvr1 acvr1c acvr1c LOC100711454 LOC100711454 smad1 smad1 chrd chrd ltbp1 ltbp1 I3JZ47_ORENI I3JZ47_ORENI kera kera LOC100698527 LOC100698527 I3K1Z3_ORENI I3K1Z3_ORENI I3K2B3_ORENI I3K2B3_ORENI LOC100696093 LOC100696093 ACVR2A ACVR2A bgn bgn smad9 smad9 LOC100698095 LOC100698095 LOC100702473 LOC100702473 inha inha LOC100712573 LOC100712573 fst fst LOC100709151 LOC100709151 bmp6 bmp6 LOC100710008 LOC100710008 smad3 smad3 LOC100710325 LOC100710325 nodal nodal LOC106098551 LOC106098551 gdf3 gdf3 LOC100691773 LOC100691773 LOC100698114 LOC100698114 LOC100711883 LOC100711883 LOC100695129 LOC100695129 Zfyve9 Zfyve9 LOC100694608 LOC100694608 LOC100699905 LOC100699905 LOC100694220 LOC100694220 prelp prelp LOC100693128 LOC100693128 TGFBR2 TGFBR2 LOC100701694 LOC100701694 gdf10 gdf10 tgfb3 tgfb3 GREM1 GREM1 LOC100695597 LOC100695597 LOC100700968 LOC100700968 LOC100706019 LOC100706019 I3KLA2_ORENI I3KLA2_ORENI LOC100709787 LOC100709787 I3IZA5_ORENI I3IZA5_ORENI tgfb2 tgfb2 smad6 smad6 LOC100695177 LOC100695177 LOC100706145 LOC100706145 ski ski LOC100699754 LOC100699754 LOC100701625 LOC100701625 LOC100693017 LOC100693017 LOC100709201 LOC100709201 NBL1 NBL1 LOC100704395 LOC100704395 gdf6 gdf6 LOC100698783 LOC100698783 LOC100708381 LOC100708381 I3K925_ORENI I3K925_ORENI LOC100710422 LOC100710422 I3JF61_ORENI I3JF61_ORENI NOG NOG fstl3 fstl3 sparc sparc LOC100691078 LOC100691078 smurf1 smurf1 LOC100705058 LOC100705058 mstn mstn LOC100704356 LOC100704356 LOC100705094 LOC100705094 LOC100711095 LOC100711095 dcn dcn grem2 grem2 SMURF2 SMURF2 LOC100707419 LOC100707419 I3KL84_ORENI I3KL84_ORENI ACVR1B ACVR1B SMAD3 SMAD3 LOC100695752 LOC100695752 LOC100700558 LOC100700558 lum lum gdf5 gdf5 LOC100691573 LOC100691573 bmp5 bmp5 LOC100693777 LOC100693777 I3KQQ1_ORENI I3KQQ1_ORENI
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
aspnAsporin. (370 aa)
ognOsteoglycin, paralog a. (283 aa)
bmp2Bone morphogenetic protein 2b. (418 aa)
ENSONIP00000001443annotation not available (1468 aa)
LOC100711913Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (507 aa)
LOC100695903Left-right determination factor. (418 aa)
bmp4Bone morphogenetic protein 4. (403 aa)
tgfbiTransforming growth factor, beta-induced. (677 aa)
I3J168_ORENIZinc finger, FYVE domain containing 9b. (868 aa)
bambiBMP and activin membrane-bound inhibitor homolog; Negatively regulates TGF-beta signaling. Belongs to the BAMBI family. (256 aa)
LOC100700916V-ski avian sarcoma viral oncogene homolog b. (687 aa)
LOC100711374Nodal-related 1. (404 aa)
bmp8aBone morphogenetic protein 8a. (452 aa)
LOC100690458Transforming growth factor beta; Belongs to the TGF-beta family. (419 aa)
LOC100694986Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1210 aa)
I3JEN4_ORENISerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (520 aa)
LOC100694653Transforming growth factor beta; Belongs to the TGF-beta family. (381 aa)
smad7Mothers against decapentaplegic homolog. (376 aa)
acvr1Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1280 aa)
acvr1cReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (493 aa)
LOC100711454TGF_BETA_2 domain-containing protein. (529 aa)
smad1Mothers against decapentaplegic homolog. (468 aa)
chrdChordin; Belongs to the chordin family. (949 aa)
ltbp1Latent transforming growth factor beta binding protein 1. (1496 aa)
I3JZ47_ORENIZinc finger, FYVE domain containing 16. (1400 aa)
keraKeratocan. (343 aa)
LOC100698527Growth differentiation factor 7. (390 aa)
I3K1Z3_ORENIUncharacterized protein. (1603 aa)
I3K2B3_ORENIReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (505 aa)
LOC100696093TGF_BETA_2 domain-containing protein. (362 aa)
ACVR2ASerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (558 aa)
bgnBiglycan; May be involved in collagen fiber assembly. Belongs to the small leucine-rich proteoglycan (SLRP) family. SLRP class I subfamily. (371 aa)
smad9Mothers against decapentaplegic homolog. (468 aa)
LOC100698095Mothers against decapentaplegic homolog. (501 aa)
LOC100702473Southpaw. (413 aa)
inhaInhibin alpha chain; Inhibins and activins inhibit and activate, respectively, the secretion of follitropin by the pituitary gland. Inhibins/activins are involved in regulating a number of diverse functions such as hypothalamic and pituitary hormone secretion, gonadal hormone secretion, germ cell development and maturation, erythroid differentiation, insulin secretion, nerve cell survival, embryonic axial development or bone growth, depending on their subunit composition; Belongs to the TGF-beta family. (346 aa)
LOC100712573Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (637 aa)
fstFollistatin a. (339 aa)
LOC100709151Forkhead box H1. (514 aa)
bmp6Bone morphogenetic protein 6. (428 aa)
LOC100710008Transforming growth factor beta; Belongs to the TGF-beta family. (408 aa)
smad3Mothers against decapentaplegic homolog. (448 aa)
LOC100710325Mothers against decapentaplegic homolog. (467 aa)
nodalNodal-related 2. (386 aa)
LOC106098551Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (614 aa)
gdf3Growth differentiation factor 3. (376 aa)
LOC100691773Fibromodulin b. (346 aa)
LOC100698114Osteoglycin, paralog b. (269 aa)
LOC100711883Uncharacterized protein. (349 aa)
LOC100695129Uncharacterized protein. (659 aa)
Zfyve9Zinc finger, FYVE domain containing 9a. (1201 aa)
LOC100694608Anti-dorsalizing morphogenic protein. (386 aa)
LOC100699905Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (501 aa)
LOC100694220Fibromodulin a. (349 aa)
prelpProline/arginine-rich end leucine-rich repeat protein. (379 aa)
LOC100693128TGF_BETA_2 domain-containing protein. (387 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (538 aa)
LOC100701694Growth differentiation factor 2. (420 aa)
gdf10Growth differentiation factor 10b. (454 aa)
tgfb3Transforming growth factor beta; Belongs to the TGF-beta family. (405 aa)
GREM1Gremlin. (182 aa)
LOC100695597Uncharacterized protein. (283 aa)
LOC100700968Noggin; Belongs to the noggin family. (211 aa)
LOC100706019Gremlin 1a, DAN family BMP antagonist. (236 aa)
I3KLA2_ORENISerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (522 aa)
LOC100709787Metalloendopeptidase. (301 aa)
I3IZA5_ORENIMothers against decapentaplegic homolog. (220 aa)
tgfb2Transforming growth factor beta; Belongs to the TGF-beta family. (422 aa)
smad6Mothers against decapentaplegic homolog. (488 aa)
LOC100695177Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (523 aa)
LOC100706145Mothers against decapentaplegic homolog. (481 aa)
skiV-ski avian sarcoma viral oncogene homolog a. (740 aa)
LOC100699754Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (516 aa)
LOC100701625Bone morphogenetic protein 7a. (425 aa)
LOC100693017Growth differentiation factor 6a. (442 aa)
LOC100709201TGF_BETA_2 domain-containing protein. (391 aa)
NBL1NBL1, DAN family BMP antagonist. (187 aa)
LOC100704395TGF_BETA_2 domain-containing protein. (390 aa)
gdf6Growth differentiation factor 6b. (436 aa)
LOC100698783Bone morphogenetic protein 10, like. (458 aa)
LOC100708381Mothers against decapentaplegic homolog. (526 aa)
I3K925_ORENISerine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (509 aa)
LOC100710422Inhibin subunit beta C. (374 aa)
I3JF61_ORENIBone morphogenetic protein 16. (580 aa)
NOGNoggin 3. (179 aa)
fstl3Follistatin-like 3 (secreted glycoprotein). (278 aa)
sparcSecreted protein, acidic, cysteine-rich (osteonectin). (332 aa)
LOC100691078E3 ubiquitin-protein ligase. (844 aa)
smurf1E3 ubiquitin-protein ligase. (745 aa)
LOC100705058Inhibin subunit beta B. (404 aa)
mstnMyostatin b. (376 aa)
LOC100704356Periostin, osteoblast specific factor b. (817 aa)
LOC100705094Mothers against decapentaplegic homolog. (765 aa)
LOC100711095Zgc:113307. (375 aa)
dcnDecorin; May affect the rate of fibrils formation. (359 aa)
grem2Gremlin 2, DAN family BMP antagonist a. (195 aa)
SMURF2E3 ubiquitin-protein ligase. (747 aa)
LOC100707419Bone morphogenetic protein 7b. (451 aa)
I3KL84_ORENIInhibin subunit beta Aa. (427 aa)
ACVR1BReceptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. (506 aa)
SMAD3Mothers against decapentaplegic homolog. (425 aa)
LOC100695752Bone morphogenetic protein 10. (480 aa)
LOC100700558Mothers against decapentaplegic homolog. (550 aa)
lumLumican. (383 aa)
gdf5Growth differentiation factor 5. (479 aa)
LOC100691573Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (566 aa)
bmp5Bone morphogenetic protein 5. (458 aa)
LOC100693777Mothers against decapentaplegic homolog. (500 aa)
I3KQQ1_ORENISKI-like proto-oncogene a. (655 aa)
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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