5 items (Oreochromis niloticus) - STRING interaction network

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Your Input:
	ENSONIP00000064374	Small ubiquitin-related modifier 2. (90 aa)
	ube2i	Ubiquitin-conjugating enzyme E2Ib; Belongs to the ubiquitin-conjugating enzyme family. (158 aa)
	uba2	SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family. (657 aa)
	sae1	SUMO1 activating enzyme subunit 1. (381 aa)
	sumo1	Small ubiquitin-related modifier. (101 aa)

Your Current Organism:

Oreochromis niloticus

NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSONIP00000064374	sae1	ENSONIP00000064374	ENSONIP00000072203	Small ubiquitin-related modifier 2.	SUMO1 activating enzyme subunit 1.	0.899
ENSONIP00000064374	sumo1	ENSONIP00000064374	ENSONIP00000072692	Small ubiquitin-related modifier 2.	Small ubiquitin-related modifier.	0.655
ENSONIP00000064374	uba2	ENSONIP00000064374	ENSONIP00000069482	Small ubiquitin-related modifier 2.	SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family.	0.892
ENSONIP00000064374	ube2i	ENSONIP00000064374	ENSONIP00000066419	Small ubiquitin-related modifier 2.	Ubiquitin-conjugating enzyme E2Ib; Belongs to the ubiquitin-conjugating enzyme family.	0.981
sae1	ENSONIP00000064374	ENSONIP00000072203	ENSONIP00000064374	SUMO1 activating enzyme subunit 1.	Small ubiquitin-related modifier 2.	0.899
sae1	sumo1	ENSONIP00000072203	ENSONIP00000072692	SUMO1 activating enzyme subunit 1.	Small ubiquitin-related modifier.	0.987
sae1	uba2	ENSONIP00000072203	ENSONIP00000069482	SUMO1 activating enzyme subunit 1.	SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family.	0.999
sae1	ube2i	ENSONIP00000072203	ENSONIP00000066419	SUMO1 activating enzyme subunit 1.	Ubiquitin-conjugating enzyme E2Ib; Belongs to the ubiquitin-conjugating enzyme family.	0.960
sumo1	ENSONIP00000064374	ENSONIP00000072692	ENSONIP00000064374	Small ubiquitin-related modifier.	Small ubiquitin-related modifier 2.	0.655
sumo1	sae1	ENSONIP00000072692	ENSONIP00000072203	Small ubiquitin-related modifier.	SUMO1 activating enzyme subunit 1.	0.987
sumo1	uba2	ENSONIP00000072692	ENSONIP00000069482	Small ubiquitin-related modifier.	SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family.	0.998
sumo1	ube2i	ENSONIP00000072692	ENSONIP00000066419	Small ubiquitin-related modifier.	Ubiquitin-conjugating enzyme E2Ib; Belongs to the ubiquitin-conjugating enzyme family.	0.997
uba2	ENSONIP00000064374	ENSONIP00000069482	ENSONIP00000064374	SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family.	Small ubiquitin-related modifier 2.	0.892
uba2	sae1	ENSONIP00000069482	ENSONIP00000072203	SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family.	SUMO1 activating enzyme subunit 1.	0.999
uba2	sumo1	ENSONIP00000069482	ENSONIP00000072692	SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family.	Small ubiquitin-related modifier.	0.998
uba2	ube2i	ENSONIP00000069482	ENSONIP00000066419	SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family.	Ubiquitin-conjugating enzyme E2Ib; Belongs to the ubiquitin-conjugating enzyme family.	0.969
ube2i	ENSONIP00000064374	ENSONIP00000066419	ENSONIP00000064374	Ubiquitin-conjugating enzyme E2Ib; Belongs to the ubiquitin-conjugating enzyme family.	Small ubiquitin-related modifier 2.	0.981
ube2i	sae1	ENSONIP00000066419	ENSONIP00000072203	Ubiquitin-conjugating enzyme E2Ib; Belongs to the ubiquitin-conjugating enzyme family.	SUMO1 activating enzyme subunit 1.	0.960
ube2i	sumo1	ENSONIP00000066419	ENSONIP00000072692	Ubiquitin-conjugating enzyme E2Ib; Belongs to the ubiquitin-conjugating enzyme family.	Small ubiquitin-related modifier.	0.997
ube2i	uba2	ENSONIP00000066419	ENSONIP00000069482	Ubiquitin-conjugating enzyme E2Ib; Belongs to the ubiquitin-conjugating enzyme family.	SUMO-activating enzyme subunit 2; The heterodimer acts as an E1 ligase for SUMO1, SUMO2, SUMO3, and probably SUMO4. It mediates ATP-dependent activation of SUMO proteins followed by formation of a thioester bond between a SUMO protein and a conserved active site cysteine residue on UBA2/SAE2. Belongs to the ubiquitin-activating E1 family.	0.969