(16 nodes) L27 domain, C-terminal, and Dopamine Neurotransmitter Release Cycle network (Oreochromis niloticus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	lin7a	Protein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family. (218 aa)
	LOC100691548	Uncharacterized protein; Belongs to the MAGUK family. (661 aa)
	I3JG31_ORENI	Amyloid beta (A4) precursor protein-binding, family A, member 2b. (774 aa)
	LOC100706664	Amyloid beta precursor protein binding family A member 3. (724 aa)
	LOC100690163	Membrane protein, palmitoylated 2b (MAGUK p55 subfamily member 2); Belongs to the MAGUK family. (567 aa)
	APBA1	Amyloid beta precursor protein binding family A member 1. (1057 aa)
	LOC100701914	Membrane protein, palmitoylated 2a (MAGUK p55 subfamily member 2); Belongs to the MAGUK family. (577 aa)
	LOC100696258	Amyloid beta (A4) precursor protein-binding, family A, member 2a. (833 aa)
	lin7c	Protein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family. (203 aa)
	mpp1	Membrane protein, palmitoylated 1; Belongs to the MAGUK family. (484 aa)
	LOC100698346	Calcium/calmodulin-dependent protein kinase (CaM kinase) II delta 2. (519 aa)
	CASK	Calcium/calmodulin dependent serine protein kinase; Belongs to the MAGUK family. (950 aa)
	LOC100693503	Calcium/calmodulin-dependent serine protein kinase b; Belongs to the MAGUK family. (944 aa)
	LOC100698823	Amyloid beta A4 precursor protein-binding family A member 1. (1149 aa)
	LOC100694809	Membrane protein, palmitoylated 6a (MAGUK p55 subfamily member 6); Belongs to the MAGUK family. (568 aa)
	Lin7b	Protein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family. (253 aa)

Your Current Organism:

Oreochromis niloticus

NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
APBA1	CASK	ENSONIP00000029001	ENSONIP00000051251	Amyloid beta precursor protein binding family A member 1.	Calcium/calmodulin dependent serine protein kinase; Belongs to the MAGUK family.	0.956
APBA1	LOC100690163	ENSONIP00000029001	ENSONIP00000025075	Amyloid beta precursor protein binding family A member 1.	Membrane protein, palmitoylated 2b (MAGUK p55 subfamily member 2); Belongs to the MAGUK family.	0.657
APBA1	LOC100691548	ENSONIP00000029001	ENSONIP00000005653	Amyloid beta precursor protein binding family A member 1.	Uncharacterized protein; Belongs to the MAGUK family.	0.657
APBA1	LOC100693503	ENSONIP00000029001	ENSONIP00000060090	Amyloid beta precursor protein binding family A member 1.	Calcium/calmodulin-dependent serine protein kinase b; Belongs to the MAGUK family.	0.956
APBA1	LOC100694809	ENSONIP00000029001	ENSONIP00000073409	Amyloid beta precursor protein binding family A member 1.	Membrane protein, palmitoylated 6a (MAGUK p55 subfamily member 6); Belongs to the MAGUK family.	0.657
APBA1	LOC100698346	ENSONIP00000029001	ENSONIP00000049713	Amyloid beta precursor protein binding family A member 1.	Calcium/calmodulin-dependent protein kinase (CaM kinase) II delta 2.	0.659
APBA1	LOC100701914	ENSONIP00000029001	ENSONIP00000029540	Amyloid beta precursor protein binding family A member 1.	Membrane protein, palmitoylated 2a (MAGUK p55 subfamily member 2); Belongs to the MAGUK family.	0.657
APBA1	Lin7b	ENSONIP00000029001	ENSONIP00000080420	Amyloid beta precursor protein binding family A member 1.	Protein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family.	0.597
APBA1	lin7a	ENSONIP00000029001	ENSONIP00000000094	Amyloid beta precursor protein binding family A member 1.	Protein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family.	0.597
APBA1	lin7c	ENSONIP00000029001	ENSONIP00000031248	Amyloid beta precursor protein binding family A member 1.	Protein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family.	0.597
APBA1	mpp1	ENSONIP00000029001	ENSONIP00000039517	Amyloid beta precursor protein binding family A member 1.	Membrane protein, palmitoylated 1; Belongs to the MAGUK family.	0.782
CASK	APBA1	ENSONIP00000051251	ENSONIP00000029001	Calcium/calmodulin dependent serine protein kinase; Belongs to the MAGUK family.	Amyloid beta precursor protein binding family A member 1.	0.956
CASK	I3JG31_ORENI	ENSONIP00000051251	ENSONIP00000007822	Calcium/calmodulin dependent serine protein kinase; Belongs to the MAGUK family.	Amyloid beta (A4) precursor protein-binding, family A, member 2b.	0.956
CASK	LOC100693503	ENSONIP00000051251	ENSONIP00000060090	Calcium/calmodulin dependent serine protein kinase; Belongs to the MAGUK family.	Calcium/calmodulin-dependent serine protein kinase b; Belongs to the MAGUK family.	0.770
CASK	LOC100696258	ENSONIP00000051251	ENSONIP00000029605	Calcium/calmodulin dependent serine protein kinase; Belongs to the MAGUK family.	Amyloid beta (A4) precursor protein-binding, family A, member 2a.	0.956
CASK	LOC100698823	ENSONIP00000051251	ENSONIP00000065024	Calcium/calmodulin dependent serine protein kinase; Belongs to the MAGUK family.	Amyloid beta A4 precursor protein-binding family A member 1.	0.956
CASK	LOC100706664	ENSONIP00000051251	ENSONIP00000015943	Calcium/calmodulin dependent serine protein kinase; Belongs to the MAGUK family.	Amyloid beta precursor protein binding family A member 3.	0.956
CASK	Lin7b	ENSONIP00000051251	ENSONIP00000080420	Calcium/calmodulin dependent serine protein kinase; Belongs to the MAGUK family.	Protein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family.	0.992
CASK	lin7a	ENSONIP00000051251	ENSONIP00000000094	Calcium/calmodulin dependent serine protein kinase; Belongs to the MAGUK family.	Protein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family.	0.992
CASK	lin7c	ENSONIP00000051251	ENSONIP00000031248	Calcium/calmodulin dependent serine protein kinase; Belongs to the MAGUK family.	Protein lin-7 homolog; Plays a role in establishing and maintaining the asymmetric distribution of channels and receptors at the plasma membrane of polarized cells; Belongs to the lin-7 family.	0.992