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usp16 | Ubiquitin carboxyl-terminal hydrolase 16; Specifically deubiquitinates 'Lys-120' of histone H2A (H2AK119Ub), a specific tag for epigenetic transcriptional repression, thereby acting as a coactivator. Deubiquitination of histone H2A is a prerequisite for subsequent phosphorylation at 'Ser-11' of histone H3 (H3S10ph), and is required for chromosome segregation when cells enter into mitosis. Regulates Hox gene expression via histone H2A deubiquitination. Prefers nucleosomal substrates. Does not deubiquitinate histone H2B. (859 aa) | ||||
znf341 | Zinc finger protein 341. (914 aa) | ||||
rnf103 | Ring finger protein 103. (700 aa) | ||||
I3KFT1_ORENI | Ubiquitin specific peptidase 54b. (1328 aa) | ||||
rwdd2b | RWD domain containing 2B. (374 aa) |