(64 nodes) Mixed, incl. Other glycan degradation, and Glycosphingolipid metabolism network (Oreochromis niloticus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	fuca2	Alpha-L-fucosidase; Alpha-L-fucosidase is responsible for hydrolyzing the alpha- 1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. (454 aa)
	fam149b1	Family with sequence similarity 149 member B1. (683 aa)
	gla	Alpha-galactosidase. (430 aa)
	galns	Galactosamine (N-acetyl)-6-sulfatase. (526 aa)
	neu4	Sialidase 4. (498 aa)
	A3GALT2	Alpha 1,3-galactosyltransferase 2. (370 aa)
	gm2a	GM2 ganglioside activator. (195 aa)
	raly	RALY heterogeneous nuclear ribonucleoprotein. (291 aa)
	kbtbd3	Kelch repeat and BTB (POZ) domain containing 3. (633 aa)
	neu3a	Sialidase 3a. (408 aa)
	LOC100709410	Beta-galactosidase. (640 aa)
	LOC100709681	Beta-galactosidase. (605 aa)
	ENSONIP00000009037	Alpha-1,3-galactosyltransferase 2-like. (307 aa)
	I3JPS6_ORENI	Stanniocalcin 2b. (272 aa)
	G6PC2	Glucose-6-phosphatase catalytic subunit 2. (358 aa)
	LOC100708354	Galactosidase, beta 1-like; Belongs to the glycosyl hydrolase 35 family. (644 aa)
	man2b2	Alpha-mannosidase. (1009 aa)
	LOC100709839	Beta-galactosidase. (638 aa)
	st8sia1	ST8 alpha-N-acetyl-neuraminide alpha-2,8-sialyltransferase 1; Belongs to the glycosyltransferase 29 family. (335 aa)
	LOC100707042	Uncharacterized protein. (419 aa)
	LOC100702967	Si:ch211-236l14.4; Belongs to the glycosyl hydrolase 31 family. (693 aa)
	man2c1	Mannosidase, alpha, class 2C, member 1. (1023 aa)
	glb1	Beta-galactosidase. (663 aa)
	LOC106098442	Sialidase domain-containing protein. (397 aa)
	LOC100534530	Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (352 aa)
	g6pc	Glucose-6-phosphatase; Belongs to the glucose-6-phosphatase family. (354 aa)
	LOC100690587	ST3 beta-galactoside alpha-2,3-sialyltransferase 7; Belongs to the glycosyltransferase 29 family. (393 aa)
	GRID1	Glutamate receptor, ionotropic, delta 1b. (1023 aa)
	b4galnt1	Beta-1,4 N-acetylgalactosaminyltransferase. (533 aa)
	I3KT17_ORENI	Glyco_18 domain-containing protein; Belongs to the glycosyl hydrolase 18 family. (303 aa)
	ctsa	Carboxypeptidase; Belongs to the peptidase S10 family. (466 aa)
	man2b1	Alpha-mannosidase. (892 aa)
	gck	Phosphotransferase. (478 aa)
	LOC100699221	Uncharacterized protein. (363 aa)
	gal3st1	Galactose-3-O-sulfotransferase 1a. (437 aa)
	ENSONIP00000033589	annotation not available (619 aa)
	ENSONIP00000036222	annotation not available (200 aa)
	I3JJJ3_ORENI	Uncharacterized protein. (327 aa)
	ENSONIP00000040558	annotation not available (318 aa)
	g6pc3	Glucose-6-phosphatase 3. (339 aa)
	ENSONIP00000044879	Globoside alpha-1,3-N-acetylgalactosaminyltransferase 1 isoform X1. (358 aa)
	ENSONIP00000045346	annotation not available (1348 aa)
	ENSONIP00000046015	N-acetyllactosaminide alpha-1,3-galactosyltransferase isoform X1. (318 aa)
	LOC100705425	Beta-1,4 N-acetylgalactosaminyltransferase. (592 aa)
	St3gal5	Lactosylceramide alpha-2,3-sialyltransferase (sialyltransferase 9). (351 aa)
	alkbh8	AlkB homolog 8, tRNA methyltransferase. (741 aa)
	LOC100704949	Globoside alpha-1,3-N-acetylgalactosaminyltransferase 1, like 2. (350 aa)
	adpgk	ADP-dependent glucokinase. (497 aa)
	hexd	Hexosaminidase (glycosyl hydrolase family 20, catalytic domain) containing. (482 aa)
	I3JLS2_ORENI	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6. (391 aa)
	LOC100703330	Uncharacterized protein. (1893 aa)
	stc2	Stanniocalcin 2. (286 aa)
	I3JPS1_ORENI	Biorientation of chromosomes in cell division 1. (162 aa)
	LOC100706635	Carboxypeptidase; Belongs to the peptidase S10 family. (468 aa)
	neu3e	Sialidase-2/3/4. (396 aa)
	Fuca1	Alpha-L-fucosidase; Alpha-L-fucosidase is responsible for hydrolyzing the alpha- 1,6-linked fucose joined to the reducing-end N-acetylglucosamine of the carbohydrate moieties of glycoproteins. (516 aa)
	cpvl	Carboxypeptidase vitellogenic like; Belongs to the peptidase S10 family. (489 aa)
	LOC100699774	ADP-dependent glucokinase 2. (493 aa)
	hexa	Beta-hexosaminidase. (596 aa)
	ENSONIP00000070284	annotation not available (2306 aa)
	neu1	Neuraminidase 1. (405 aa)
	naga	Alpha-galactosidase. (435 aa)
	hexb	Beta-hexosaminidase. (549 aa)
	manba	Mannosidase, beta A, lysosomal. (903 aa)

Your Current Organism:

Oreochromis niloticus

NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
A3GALT2	I3JLS2_ORENI	ENSONIP00000004932	ENSONIP00000055043	Alpha 1,3-galactosyltransferase 2.	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6.	0.851
A3GALT2	LOC100708354	ENSONIP00000004932	ENSONIP00000011338	Alpha 1,3-galactosyltransferase 2.	Galactosidase, beta 1-like; Belongs to the glycosyl hydrolase 35 family.	0.800
A3GALT2	glb1	ENSONIP00000004932	ENSONIP00000022152	Alpha 1,3-galactosyltransferase 2.	Beta-galactosidase.	0.800
ENSONIP00000009037	I3JLS2_ORENI	ENSONIP00000009037	ENSONIP00000055043	Alpha-1,3-galactosyltransferase 2-like.	UDP-Gal:betaGlcNAc beta 1,4- galactosyltransferase, polypeptide 6.	0.815
ENSONIP00000009037	LOC100708354	ENSONIP00000009037	ENSONIP00000011338	Alpha-1,3-galactosyltransferase 2-like.	Galactosidase, beta 1-like; Belongs to the glycosyl hydrolase 35 family.	0.801
ENSONIP00000009037	glb1	ENSONIP00000009037	ENSONIP00000022152	Alpha-1,3-galactosyltransferase 2-like.	Beta-galactosidase.	0.801
ENSONIP00000033589	ENSONIP00000036222	ENSONIP00000033589	ENSONIP00000036222	annotation not available	annotation not available	0.417
ENSONIP00000033589	I3JPS1_ORENI	ENSONIP00000033589	ENSONIP00000057243	annotation not available	Biorientation of chromosomes in cell division 1.	0.417
ENSONIP00000033589	I3JPS6_ORENI	ENSONIP00000033589	ENSONIP00000010870	annotation not available	Stanniocalcin 2b.	0.417
ENSONIP00000033589	LOC100708354	ENSONIP00000033589	ENSONIP00000011338	annotation not available	Galactosidase, beta 1-like; Belongs to the glycosyl hydrolase 35 family.	0.417
ENSONIP00000033589	LOC100709410	ENSONIP00000033589	ENSONIP00000006668	annotation not available	Beta-galactosidase.	0.417
ENSONIP00000033589	LOC100709681	ENSONIP00000033589	ENSONIP00000006682	annotation not available	Beta-galactosidase.	0.417
ENSONIP00000033589	LOC100709839	ENSONIP00000033589	ENSONIP00000014228	annotation not available	Beta-galactosidase.	0.417
ENSONIP00000033589	glb1	ENSONIP00000033589	ENSONIP00000022152	annotation not available	Beta-galactosidase.	0.417
ENSONIP00000033589	neu1	ENSONIP00000033589	ENSONIP00000070436	annotation not available	Neuraminidase 1.	0.548
ENSONIP00000036222	ENSONIP00000033589	ENSONIP00000036222	ENSONIP00000033589	annotation not available	annotation not available	0.417
ENSONIP00000036222	ENSONIP00000040558	ENSONIP00000036222	ENSONIP00000040558	annotation not available	annotation not available	0.417
ENSONIP00000036222	ENSONIP00000045346	ENSONIP00000036222	ENSONIP00000045346	annotation not available	annotation not available	0.417
ENSONIP00000036222	ENSONIP00000070284	ENSONIP00000036222	ENSONIP00000070284	annotation not available	annotation not available	0.417
ENSONIP00000036222	LOC100706635	ENSONIP00000036222	ENSONIP00000057773	annotation not available	Carboxypeptidase; Belongs to the peptidase S10 family.	0.550