24 items (Oreochromis niloticus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	I3KG87_ORENI	Citron rho-interacting serine/threonine kinase b. (1683 aa)
	cdk1	Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily. (336 aa)
	ush1c	USH1 protein network component harmonin. (769 aa)
	LOC100696207	Uncharacterized protein. (738 aa)
	LOC100702417	Protein kinase domain-containing protein. (866 aa)
	LOC100696908	Uncharacterized protein. (660 aa)
	ENSONIP00000036143	annotation not available (449 aa)
	I3KB03_ORENI	Protein kinase domain-containing protein. (866 aa)
	I3KTN0_ORENI	Citron Rho-interacting kinase; Plays a role in cytokinesis. Displays serine/threonine protein kinase activity; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (2006 aa)
	fbxl15	F-box and leucine-rich repeat protein 15. (292 aa)
	fbxl22	F-box and leucine-rich repeat protein 22. (306 aa)
	fbxl6	F-box domain-containing protein. (521 aa)
	CDC25B	Cell division cycle 25B. (571 aa)
	Chek2	Checkpoint kinase 2. (482 aa)
	kdm8	Lysine (K)-specific demethylase 8. (419 aa)
	LOC100702285	Protein phosphatase, Mg2+/Mn2+ dependent, 1Db. (572 aa)
	chek1	Checkpoint kinase 1; Belongs to the protein kinase superfamily. (460 aa)
	mastl	Microtubule associated serine/threonine kinase-like. (853 aa)
	LOC100695493	Endosulfine alpha a; Protein phosphatase inhibitor that specifically inhibits protein phosphatase 2A (PP2A) during mitosis. Belongs to the endosulfine family. (169 aa)
	ppm1d	Protein phosphatase, Mg2+/Mn2+ dependent, 1Da. (557 aa)
	skp2	S-phase kinase-associated protein 2, E3 ubiquitin protein ligase. (419 aa)
	I3J272_ORENI	F-box domain-containing protein. (392 aa)
	I3JH22_ORENI	Si:dkey-16p21.7. (764 aa)
	ENSONIP00000075015	Forkhead box M1. (518 aa)

Your Current Organism:

Oreochromis niloticus

NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
CDC25B	Chek2	ENSONIP00000015484	ENSONIP00000000942	Cell division cycle 25B.	Checkpoint kinase 2.	0.994
CDC25B	ENSONIP00000036143	ENSONIP00000015484	ENSONIP00000036143	Cell division cycle 25B.	annotation not available	0.649
CDC25B	ENSONIP00000075015	ENSONIP00000015484	ENSONIP00000075015	Cell division cycle 25B.	Forkhead box M1.	0.649
CDC25B	I3JH22_ORENI	ENSONIP00000015484	ENSONIP00000078583	Cell division cycle 25B.	Si:dkey-16p21.7.	0.762
CDC25B	I3KB03_ORENI	ENSONIP00000015484	ENSONIP00000033301	Cell division cycle 25B.	Protein kinase domain-containing protein.	0.762
CDC25B	LOC100696207	ENSONIP00000015484	ENSONIP00000060415	Cell division cycle 25B.	Uncharacterized protein.	0.762
CDC25B	LOC100696908	ENSONIP00000015484	ENSONIP00000046504	Cell division cycle 25B.	Uncharacterized protein.	0.649
CDC25B	LOC100702417	ENSONIP00000015484	ENSONIP00000048394	Cell division cycle 25B.	Protein kinase domain-containing protein.	0.762
CDC25B	cdk1	ENSONIP00000015484	ENSONIP00000067132	Cell division cycle 25B.	Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily.	0.990
CDC25B	chek1	ENSONIP00000015484	ENSONIP00000006188	Cell division cycle 25B.	Checkpoint kinase 1; Belongs to the protein kinase superfamily.	0.997
Chek2	CDC25B	ENSONIP00000000942	ENSONIP00000015484	Checkpoint kinase 2.	Cell division cycle 25B.	0.994
Chek2	LOC100702285	ENSONIP00000000942	ENSONIP00000002398	Checkpoint kinase 2.	Protein phosphatase, Mg2+/Mn2+ dependent, 1Db.	0.624
Chek2	cdk1	ENSONIP00000000942	ENSONIP00000067132	Checkpoint kinase 2.	Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily.	0.462
Chek2	chek1	ENSONIP00000000942	ENSONIP00000006188	Checkpoint kinase 2.	Checkpoint kinase 1; Belongs to the protein kinase superfamily.	0.991
Chek2	mastl	ENSONIP00000000942	ENSONIP00000008048	Checkpoint kinase 2.	Microtubule associated serine/threonine kinase-like.	0.628
Chek2	ppm1d	ENSONIP00000000942	ENSONIP00000013159	Checkpoint kinase 2.	Protein phosphatase, Mg2+/Mn2+ dependent, 1Da.	0.624
ENSONIP00000036143	CDC25B	ENSONIP00000036143	ENSONIP00000015484	annotation not available	Cell division cycle 25B.	0.649
ENSONIP00000036143	cdk1	ENSONIP00000036143	ENSONIP00000067132	annotation not available	Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily.	0.573
ENSONIP00000075015	CDC25B	ENSONIP00000075015	ENSONIP00000015484	Forkhead box M1.	Cell division cycle 25B.	0.649
ENSONIP00000075015	cdk1	ENSONIP00000075015	ENSONIP00000067132	Forkhead box M1.	Cyclin-dependent kinase 1; Belongs to the protein kinase superfamily.	0.573