51 items (Oreochromis niloticus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	usp8	Ubiquitin specific peptidase 8; Belongs to the peptidase C19 family. (931 aa)
	LOC100699690	Uncharacterized protein. (951 aa)
	klhdc8b	Kelch domain containing 8B. (354 aa)
	pdcd6ip	Programmed cell death 6 interacting protein. (884 aa)
	LOC100690370	Sorting nexin. (541 aa)
	kif4a	Kinesin family member 4; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1241 aa)
	lzts3	Leucine zipper putative tumor suppressor 3 isoform X1. (946 aa)
	LOC100702271	GMP_PDE_delta domain-containing protein. (256 aa)
	Efhc1	EF-hand domain (C-terminal) containing 1. (586 aa)
	KIF23	Kinesin family member 23; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (1056 aa)
	vps4a	Vacuolar protein sorting 4 homolog A; Belongs to the AAA ATPase family. (485 aa)
	LOC100710423	Leucine zipper putative tumor suppressor 2 homolog; Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. Negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta-catenin. Belongs to the LZTS2 family. (789 aa)
	racgap1	Rac GTPase activating protein 1. (648 aa)
	rab35	RAB35, member RAS oncogene family b. (201 aa)
	I3KEE6_ORENI	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family. (948 aa)
	LOC100711005	Uncharacterized protein; Belongs to the AAA ATPase family. (446 aa)
	I3KG87_ORENI	Citron rho-interacting serine/threonine kinase b. (1683 aa)
	LOC100706117	Aurora kinase B; Belongs to the protein kinase superfamily. (290 aa)
	ENSONIP00000053192	Kinesin family member 23. (562 aa)
	bbs4	Bardet-Biedl syndrome 4. (539 aa)
	ect2	Epithelial cell transforming 2. (993 aa)
	rasa1	RAS p21 protein activator (GTPase activating protein) 1a. (1063 aa)
	LOC100709328	Stathmin; Belongs to the stathmin family. (154 aa)
	SNX18	Sorting nexin. (590 aa)
	LOC100707086	Kelch domain containing 8A. (476 aa)
	rock2	Rho-associated, coiled-coil containing protein kinase 2a; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (1394 aa)
	LOC100701678	Uncharacterized protein; Belongs to the small GTPase superfamily. Arf family. (193 aa)
	jtb	Protein JTB isoform X1. (154 aa)
	unc119	Unc-119 lipid binding chaperone. (207 aa)
	LOC100703129	Sorting nexin. (579 aa)
	arl3	ADP ribosylation factor like GTPase 3; Belongs to the small GTPase superfamily. Arf family. (249 aa)
	Zfyve26	Zinc finger, FYVE domain containing 26. (2474 aa)
	ENSONIP00000024680	Nucleolar and spindle associated protein 1. (384 aa)
	I3KTN0_ORENI	Citron Rho-interacting kinase; Plays a role in cytokinesis. Displays serine/threonine protein kinase activity; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (2006 aa)
	LOC100704408	Uncharacterized protein. (634 aa)
	I3KSL0_ORENI	Si:ch1073-416j23.1. (397 aa)
	LOC100712032	EABR domain-containing protein. (435 aa)
	cep55	Centrosomal protein 55 like. (506 aa)
	efhc2	EF-hand domain (C-terminal) containing 2. (749 aa)
	incenp	Uncharacterized protein. (778 aa)
	mitd1	MIT, microtubule interacting and transport, domain containing 1. (246 aa)
	LOC100707634	Sorting nexin. (636 aa)
	snx33	Sorting nexin. (557 aa)
	LOC100704759	Actin-binding protein anillin. (1275 aa)
	anln	Anillin, actin binding protein. (1118 aa)
	I3JUV2_ORENI	Spastin; Belongs to the AAA ATPase family. (495 aa)
	VPS4B	Vacuolar protein sorting 4 homolog B; Belongs to the AAA ATPase family. (529 aa)
	LOC100703328	Si:dkey-16l2.16. (208 aa)
	Rock1	Rho-associated protein kinase; Protein kinase which is a key regulator of actin cytoskeleton and cell polarity. (1353 aa)
	LOC100692643	Leucine zipper putative tumor suppressor 2 homolog; Negative regulator of katanin-mediated microtubule severing and release from the centrosome. Required for central spindle formation and the completion of cytokinesis. Negative regulator of the Wnt signaling pathway. Represses beta-catenin-mediated transcriptional activation by promoting the nuclear exclusion of beta-catenin. Belongs to the LZTS2 family. (652 aa)
	LOC100708589	Charged multivesicular body protein 4C. (218 aa)

Your Current Organism:

Oreochromis niloticus

NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSONIP00000024680	ENSONIP00000053192	ENSONIP00000024680	ENSONIP00000053192	Nucleolar and spindle associated protein 1.	Kinesin family member 23.	0.707
ENSONIP00000024680	I3KEE6_ORENI	ENSONIP00000024680	ENSONIP00000062466	Nucleolar and spindle associated protein 1.	Kinesin-like protein; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.707
ENSONIP00000024680	I3KSL0_ORENI	ENSONIP00000024680	ENSONIP00000024106	Nucleolar and spindle associated protein 1.	Si:ch1073-416j23.1.	0.582
ENSONIP00000024680	KIF23	ENSONIP00000024680	ENSONIP00000071046	Nucleolar and spindle associated protein 1.	Kinesin family member 23; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.707
ENSONIP00000024680	LOC100704408	ENSONIP00000024680	ENSONIP00000024441	Nucleolar and spindle associated protein 1.	Uncharacterized protein.	0.582
ENSONIP00000024680	LOC100704759	ENSONIP00000024680	ENSONIP00000013689	Nucleolar and spindle associated protein 1.	Actin-binding protein anillin.	0.425
ENSONIP00000024680	LOC100706117	ENSONIP00000024680	ENSONIP00000056574	Nucleolar and spindle associated protein 1.	Aurora kinase B; Belongs to the protein kinase superfamily.	0.657
ENSONIP00000024680	LOC100712032	ENSONIP00000024680	ENSONIP00000023258	Nucleolar and spindle associated protein 1.	EABR domain-containing protein.	0.800
ENSONIP00000024680	anln	ENSONIP00000024680	ENSONIP00000013040	Nucleolar and spindle associated protein 1.	Anillin, actin binding protein.	0.425
ENSONIP00000024680	cep55	ENSONIP00000024680	ENSONIP00000020672	Nucleolar and spindle associated protein 1.	Centrosomal protein 55 like.	0.891
ENSONIP00000024680	ect2	ENSONIP00000024680	ENSONIP00000052013	Nucleolar and spindle associated protein 1.	Epithelial cell transforming 2.	0.793
ENSONIP00000024680	incenp	ENSONIP00000024680	ENSONIP00000019595	Nucleolar and spindle associated protein 1.	Uncharacterized protein.	0.408
ENSONIP00000024680	kif4a	ENSONIP00000024680	ENSONIP00000081482	Nucleolar and spindle associated protein 1.	Kinesin family member 4; Belongs to the TRAFAC class myosin-kinesin ATPase superfamily. Kinesin family.	0.882
ENSONIP00000024680	racgap1	ENSONIP00000024680	ENSONIP00000068786	Nucleolar and spindle associated protein 1.	Rac GTPase activating protein 1.	0.582
ENSONIP00000053192	ENSONIP00000024680	ENSONIP00000053192	ENSONIP00000024680	Kinesin family member 23.	Nucleolar and spindle associated protein 1.	0.707
ENSONIP00000053192	I3KG87_ORENI	ENSONIP00000053192	ENSONIP00000061030	Kinesin family member 23.	Citron rho-interacting serine/threonine kinase b.	0.580
ENSONIP00000053192	I3KSL0_ORENI	ENSONIP00000053192	ENSONIP00000024106	Kinesin family member 23.	Si:ch1073-416j23.1.	0.908
ENSONIP00000053192	I3KTN0_ORENI	ENSONIP00000053192	ENSONIP00000024476	Kinesin family member 23.	Citron Rho-interacting kinase; Plays a role in cytokinesis. Displays serine/threonine protein kinase activity; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family.	0.478
ENSONIP00000053192	LOC100704408	ENSONIP00000053192	ENSONIP00000024441	Kinesin family member 23.	Uncharacterized protein.	0.908
ENSONIP00000053192	LOC100704759	ENSONIP00000053192	ENSONIP00000013689	Kinesin family member 23.	Actin-binding protein anillin.	0.682