STRINGSTRING
LOC100708381 LOC100708381 TGFBR2 TGFBR2 dhrs3 dhrs3 zfpm2 zfpm2 LOC100693249 LOC100693249 LOC100700558 LOC100700558 ILK ILK LOC100692926 LOC100692926 LOC100705094 LOC100705094 tbx3 tbx3 sema3c sema3c LOC100690703 LOC100690703 LOC100694986 LOC100694986 LOC100695684 LOC100695684 ednra ednra sfrp2 sfrp2 LOC100706592 LOC100706592 LOC100694461 LOC100694461 LOC100712573 LOC100712573 LOC106098551 LOC106098551 LOC100706032 LOC100706032 nkx2-5 nkx2-5 LOC100701917 LOC100701917 Bmpr2 Bmpr2 edn1 edn1 LOC100704436 LOC100704436 LOC100707786 LOC100707786 I3KYD0_ORENI I3KYD0_ORENI gja5 gja5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC100708381Mothers against decapentaplegic homolog. (526 aa)
TGFBR2TGF-beta receptor type-2; Transmembrane serine/threonine kinase forming with the TGF- beta type I serine/threonine kinase receptor, TGFBR1, the non- promiscuous receptor for the TGF-beta cytokines TGFB1, TGFB2 and TGFB3. Transduces the TGFB1, TGFB2 and TGFB3 signal from the cell surface to the cytoplasm and is thus regulating a plethora of physiological and pathological processes including cell cycle arrest in epithelial and hematopoietic cells, control of mesenchymal cell proliferation and differentiation, wound healing, extracellular matrix production, immunosuppression and carcinoge [...] (538 aa)
dhrs3Dehydrogenase/reductase (SDR family) member 3b; Belongs to the short-chain dehydrogenases/reductases (SDR) family. (302 aa)
zfpm2Zinc finger protein, FOG family member 2a. (1182 aa)
LOC100693249Neuropeptide Y receptor Y7; Belongs to the G-protein coupled receptor 1 family. (387 aa)
LOC100700558Mothers against decapentaplegic homolog. (550 aa)
ILKIntegrin linked kinase. (460 aa)
LOC100692926Neuropeptide Y receptor Y2, like; Belongs to the G-protein coupled receptor 1 family. (405 aa)
LOC100705094Mothers against decapentaplegic homolog. (765 aa)
tbx3T-box transcription factor 3a. (715 aa)
sema3cSema domain, immunoglobulin domain (Ig), short basic domain, secreted, (semaphorin) 3C; Belongs to the semaphorin family. (765 aa)
LOC100690703Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (404 aa)
LOC100694986Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1210 aa)
LOC100695684Cytochrome P450, family 26, subfamily A, polypeptide 1; Belongs to the cytochrome P450 family. (488 aa)
ednraEndothelin receptor type Aa; Belongs to the G-protein coupled receptor 1 family. (442 aa)
sfrp2Secreted frizzled-related protein 2. (295 aa)
LOC100706592Endothelin receptor type Ab; Belongs to the G-protein coupled receptor 1 family. (445 aa)
LOC100694461T-box transcription factor 3b. (562 aa)
LOC100712573Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (637 aa)
LOC106098551Serine/threonine-protein kinase receptor; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (614 aa)
LOC100706032Uncharacterized protein. (336 aa)
nkx2-5NK2 homeobox 5. (319 aa)
LOC100701917Uncharacterized protein. (496 aa)
Bmpr2Receptor protein serine/threonine kinase; Belongs to the protein kinase superfamily. TKL Ser/Thr protein kinase family. TGFB receptor subfamily. (1033 aa)
edn1Endothelin 1. (202 aa)
LOC100704436Neuropeptide Y receptor Y2; Belongs to the G-protein coupled receptor 1 family. (369 aa)
LOC100707786JunE proto-oncogene, AP-1 transcription factor subunit. (347 aa)
I3KYD0_ORENIJun proto-oncogene, AP-1 transcription factor subunit; Belongs to the bZIP family. (327 aa)
gja5Gap junction protein; One gap junction consists of a cluster of closely packed pairs of transmembrane channels, the connexons, through which materials of low MW diffuse from one cell to a neighboring cell. (383 aa)
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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