STRINGSTRING
fen1 fen1 cdc6 cdc6 orc5 orc5 mms22l mms22l exd2 exd2 atr atr rmi2 rmi2 LOC100692568 LOC100692568 ENSONIP00000002713 ENSONIP00000002713 Rbm48 Rbm48 LOC100708142 LOC100708142 pole4 pole4 chaf1a chaf1a LOC100707077 LOC100707077 LOC100710041 LOC100710041 fancm fancm LOC100695591 LOC100695591 orc3 orc3 LOC100690413 LOC100690413 wdr18 wdr18 I3JAD1_ORENI I3JAD1_ORENI donson donson pola2 pola2 ddx21 ddx21 Gins2 Gins2 dtl dtl topbp1 topbp1 rpain rpain dscc1 dscc1 wdhd1 wdhd1 sde2 sde2 orc1 orc1 twnk twnk mcm5 mcm5 ENSONIP00000010727 ENSONIP00000010727 nasp nasp rfc1 rfc1 SMARCAL1 SMARCAL1 lrwd1 lrwd1 mcm4 mcm4 wrnip1 wrnip1 prim2 prim2 mgme1 mgme1 LOC100710935 LOC100710935 pif1 pif1 rfc5 rfc5 rfwd3 rfwd3 gins3 gins3 BAZ1A BAZ1A mcm10 mcm10 fbh1 fbh1 lig4 lig4 zranb3 zranb3 ENSONIP00000015699 ENSONIP00000015699 supt16h supt16h rfc3 rfc3 grwd1 grwd1 ing4 ing4 cdt1 cdt1 I3K6J4_ORENI I3K6J4_ORENI pole pole I3K8L4_ORENI I3K8L4_ORENI pola1 pola1 rfc2 rfc2 rmi1 rmi1 pold3 pold3 I3KD07_ORENI I3KD07_ORENI blm blm ticrr ticrr I3KF05_ORENI I3KF05_ORENI mcm6 mcm6 chaf1b chaf1b polk polk Slx4 Slx4 I3KHG4_ORENI I3KHG4_ORENI sirt7 sirt7 rnaseh2a rnaseh2a LOC102079736 LOC102079736 NASP NASP rnaseh1 rnaseh1 I3KRC2_ORENI I3KRC2_ORENI RRM2 RRM2 poll poll rfc4 rfc4 timeless timeless Pold1 Pold1 recql5 recql5 eme1 eme1 ENSONIP00000024927 ENSONIP00000024927 I3KVR8_ORENI I3KVR8_ORENI LOC100698471 LOC100698471 traip traip LOC100697672 LOC100697672 ZNF830 ZNF830 ENSONIP00000026881 ENSONIP00000026881 ENSONIP00000027236 ENSONIP00000027236 RPA1 RPA1 ssrp1 ssrp1 ENSONIP00000028394 ENSONIP00000028394 ENSONIP00000028447 ENSONIP00000028447 ENSONIP00000028865 ENSONIP00000028865 ttc38 ttc38 LOC100690838 LOC100690838 LOC109197824 LOC109197824 ENSONIP00000030624 ENSONIP00000030624 LOC100702321 LOC100702321 pold4 pold4 LOC102079550 LOC102079550 lig3 lig3 LOC102075526 LOC102075526 mcmbp mcmbp ENSONIP00000032560 ENSONIP00000032560 LOC100709853 LOC100709853 mcm2 mcm2 ENSONIP00000032908 ENSONIP00000032908 ENSONIP00000033825 ENSONIP00000033825 ENSONIP00000033831 ENSONIP00000033831 gins1 gins1 ENSONIP00000034389 ENSONIP00000034389 thoc1 thoc1 ENSONIP00000037861 ENSONIP00000037861 ENSONIP00000038064 ENSONIP00000038064 LOC100706337 LOC100706337 LOC100696561 LOC100696561 ddx23 ddx23 I3JAG7_ORENI I3JAG7_ORENI ENSONIP00000040462 ENSONIP00000040462 LOC100694900 LOC100694900 rad51 rad51 LOC102082614 LOC102082614 ENSONIP00000042121 ENSONIP00000042121 polq polq prim1 prim1 LOC109195818 LOC109195818 ENSONIP00000042661 ENSONIP00000042661 ENSONIP00000043597 ENSONIP00000043597 cdc45 cdc45 ENSONIP00000044270 ENSONIP00000044270 ENSONIP00000044374 ENSONIP00000044374 ENSONIP00000044851 ENSONIP00000044851 kin kin ENSONIP00000045252 ENSONIP00000045252 LOC109203110 LOC109203110 ENSONIP00000045758 ENSONIP00000045758 ENSONIP00000046147 ENSONIP00000046147 Zpr1 Zpr1 dna2 dna2 ENSONIP00000047167 ENSONIP00000047167 mre11 mre11 LOC100705387 LOC100705387 ENSONIP00000049246 ENSONIP00000049246 LOC100706185 LOC100706185 ENSONIP00000050655 ENSONIP00000050655 gmnc gmnc LOC100709275 LOC100709275 ENSONIP00000051286 ENSONIP00000051286 ENSONIP00000051374 ENSONIP00000051374 ENSONIP00000052198 ENSONIP00000052198 ENSONIP00000052505 ENSONIP00000052505 LOC100694815 LOC100694815 ENSONIP00000052945 ENSONIP00000052945 ENSONIP00000053191 ENSONIP00000053191 ENSONIP00000053303 ENSONIP00000053303 LOC100698382 LOC100698382 ENSONIP00000054953 ENSONIP00000054953 MCM7 MCM7 chtf8 chtf8 NFIB NFIB ENSONIP00000055662 ENSONIP00000055662 I3K3K4_ORENI I3K3K4_ORENI ENSONIP00000055981 ENSONIP00000055981 polg polg Orc4 Orc4 ENSONIP00000056833 ENSONIP00000056833 ENSONIP00000057198 ENSONIP00000057198 ENSONIP00000057227 ENSONIP00000057227 LOC109202971 LOC109202971 mcm3 mcm3 ENSONIP00000058387 ENSONIP00000058387 cenpx cenpx ENSONIP00000059673 ENSONIP00000059673 ENSONIP00000059694 ENSONIP00000059694 ENSONIP00000060165 ENSONIP00000060165 ENSONIP00000060807 ENSONIP00000060807 ENSONIP00000060809 ENSONIP00000060809 I3IUD3_ORENI I3IUD3_ORENI ENSONIP00000061011 ENSONIP00000061011 ENSONIP00000061033 ENSONIP00000061033 ENSONIP00000061534 ENSONIP00000061534 ENSONIP00000062846 ENSONIP00000062846 LOC102078113 LOC102078113 ENSONIP00000063711 ENSONIP00000063711 Primpol Primpol ENSONIP00000064007 ENSONIP00000064007 LOC109196932 LOC109196932 ddx11 ddx11 LOC109195020 LOC109195020 ENSONIP00000065323 ENSONIP00000065323 LOC109197015 LOC109197015 pole3 pole3 polg2 polg2 atrx atrx ENSONIP00000066486 ENSONIP00000066486 ENSONIP00000066709 ENSONIP00000066709 ENSONIP00000066808 ENSONIP00000066808 ENSONIP00000066865 ENSONIP00000066865 nfic nfic ENSONIP00000067938 ENSONIP00000067938 ENSONIP00000068385 ENSONIP00000068385 ENSONIP00000068657 ENSONIP00000068657 ENSONIP00000069225 ENSONIP00000069225 ENSONIP00000069362 ENSONIP00000069362 ENSONIP00000069543 ENSONIP00000069543 ENSONIP00000069610 ENSONIP00000069610 rpa1 rpa1 ENSONIP00000070103 ENSONIP00000070103 pcna pcna LOC100711479 LOC100711479 ENSONIP00000070673 ENSONIP00000070673 ENSONIP00000071466 ENSONIP00000071466 ENSONIP00000071769 ENSONIP00000071769 ENSONIP00000072466 ENSONIP00000072466 ENSONIP00000072470 ENSONIP00000072470 ENSONIP00000072736 ENSONIP00000072736 tatdn1 tatdn1 ENSONIP00000074207 ENSONIP00000074207 LOC100701915 LOC100701915 ENSONIP00000074985 ENSONIP00000074985 pold2 pold2 Tipin Tipin polb polb LOC109200336 LOC109200336 ENSONIP00000076308 ENSONIP00000076308 recql recql ENSONIP00000076896 ENSONIP00000076896 rpa3 rpa3 ENSONIP00000077100 ENSONIP00000077100 ENSONIP00000077188 ENSONIP00000077188 ENSONIP00000077558 ENSONIP00000077558 ssbp1 ssbp1 gins4 gins4 ENSONIP00000078769 ENSONIP00000078769 ENSONIP00000079047 ENSONIP00000079047 LOC109200249 LOC109200249 LOC100695351 LOC100695351 noc3l noc3l LOC102077867 LOC102077867 pole2 pole2
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
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colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
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fen1Flap endonuclease 1; Structure-specific nuclease with 5'-flap endonuclease and 5'- 3' exonuclease activities involved in DNA replication and repair. During DNA replication, cleaves the 5'-overhanging flap structure that is generated by displacement synthesis when DNA polymerase encounters the 5'-end of a downstream Okazaki fragment. It enters the flap from the 5'-end and then tracks to cleave the flap base, leaving a nick for ligation. Also involved in the long patch base excision repair (LP-BER) pathway, by cleaving within the apurinic/apyrimidinic (AP) site- terminated flap. Acts as [...] (383 aa)
cdc6Cell division control protein; Involved in the initiation of DNA replication. Also participates in checkpoint controls that ensure DNA replication is completed before mitosis is initiated; Belongs to the CDC6/cdc18 family. (604 aa)
orc5Origin recognition complex, subunit 5. (445 aa)
mms22lMMS22-like, DNA repair protein. (1233 aa)
exd2Exonuclease 3'-5' domain containing 2. (640 aa)
atrATR serine/threonine kinase; Belongs to the PI3/PI4-kinase family. (2554 aa)
rmi2RecQ mediated genome instability 2. (146 aa)
LOC100692568Cyclin E2; Belongs to the cyclin family. (397 aa)
ENSONIP00000002713annotation not available (760 aa)
Rbm48RNA binding motif protein 48. (345 aa)
LOC100708142SCY domain-containing protein. (126 aa)
pole4Polymerase (DNA-directed), epsilon 4, accessory subunit. (128 aa)
chaf1aChromatin assembly factor 1, subunit A (p150). (800 aa)
LOC100707077Geminin DNA replication inhibitor. (211 aa)
LOC100710041Ribonucleotide reductase M2 b. (379 aa)
fancmUncharacterized protein. (2090 aa)
LOC100695591Tonsoku-like, DNA repair protein. (1445 aa)
orc3Origin recognition complex, subunit 3. (720 aa)
LOC100690413Uncharacterized protein. (1900 aa)
wdr18WD repeat domain 18. (431 aa)
I3JAD1_ORENINuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. (516 aa)
donsonUncharacterized protein. (612 aa)
pola2DNA polymerase alpha subunit B; Accessory subunit of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which plays an essential role in the initiation of DNA synthesis. (602 aa)
ddx21DEAD (Asp-Glu-Ala-Asp) box helicase 21. (812 aa)
Gins2DNA replication complex GINS protein PSF2; Belongs to the GINS2/PSF2 family. (212 aa)
dtlDenticleless E3 ubiquitin protein ligase homolog (Drosophila). (661 aa)
topbp1DNA topoisomerase II binding protein 1. (1514 aa)
rpainRPA interacting protein. (226 aa)
dscc1DNA replication and sister chromatid cohesion 1. (407 aa)
wdhd1WD repeat and HMG-box DNA binding protein 1. (1144 aa)
sde2SDE2 telomere maintenance homolog (S. pombe). (416 aa)
orc1Origin recognition complex subunit 1; Component of the origin recognition complex (ORC) that binds origins of replication. DNA-binding is ATP-dependent, however specific DNA sequences that define origins of replication have not been identified so far. ORC is required to assemble the pre-replication complex necessary to initiate DNA replication. (901 aa)
twnkTwinkle mtDNA helicase. (720 aa)
mcm5DNA helicase; Belongs to the MCM family. (737 aa)
ENSONIP00000010727Geminin. (215 aa)
naspNuclear autoantigenic sperm protein (histone-binding). (518 aa)
rfc1Replication factor C subunit 1. (1169 aa)
SMARCAL1SWI/SNF related, matrix associated, actin dependent regulator of chromatin, subfamily a-like 1; Belongs to the SNF2/RAD54 helicase family. SMARCAL1 subfamily. (900 aa)
lrwd1Leucine-rich repeats and WD repeat domain containing 1. (739 aa)
mcm4DNA helicase; Belongs to the MCM family. (860 aa)
wrnip1WRN helicase interacting protein 1. (604 aa)
prim2DNA primase large subunit; Regulatory subunit of the DNA primase complex and component of the DNA polymerase alpha complex (also known as the alpha DNA polymerase-primase complex) which play an essential role in the initiation of DNA synthesis. The primase subunit of the polymerase alpha complex initiates DNA synthesis by oligomerising short RNA primers on both leading and lagging strands. (513 aa)
mgme1Mitochondrial genome maintenance exonuclease 1; Metal-dependent single-stranded DNA (ssDNA) exonuclease involved in mitochondrial genome maintenance. Has preference for 5'-3' exonuclease activity. Necessary for maintenance of proper 7S DNA levels. Probably involved in mitochondrial DNA (mtDNA) repair. Belongs to the MGME1 family. (346 aa)
LOC100710935DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (747 aa)
pif1ATP-dependent DNA helicase PIF1; DNA-dependent ATPase and 5'-3' DNA helicase required for the maintenance of both mitochondrial and nuclear genome stability. (657 aa)
rfc5Replication factor C (activator 1) 5. (341 aa)
rfwd3Ring finger and WD repeat domain 3. (670 aa)
gins3GINS complex subunit 3. (211 aa)
BAZ1ABromodomain adjacent to zinc finger domain 1A. (1353 aa)
mcm10Minichromosome maintenance 10 replication initiation factor. (894 aa)
fbh1F-box DNA helicase 1. (1077 aa)
lig4DNA ligase. (910 aa)
zranb3Zinc finger, RAN-binding domain containing 3. (1150 aa)
ENSONIP00000015699Deoxynucleoside triphosphate triphosphohydrolase SAMHD1-like. (431 aa)
supt16hSPT16 homolog, facilitates chromatin remodeling subunit. (1109 aa)
rfc3Replication factor C (activator 1) 3. (356 aa)
grwd1Glutamate-rich WD repeat containing 1. (451 aa)
ing4Inhibitor of growth protein. (249 aa)
cdt1Chromatin licensing and DNA replication factor 1. (556 aa)
I3K6J4_ORENIUncharacterized protein. (849 aa)
poleDNA polymerase epsilon catalytic subunit; DNA polymerase II participates in chromosomal DNA replication; Belongs to the DNA polymerase type-B family. (2292 aa)
I3K8L4_ORENICyclin-dependent kinase 2 interacting protein. (203 aa)
pola1DNA polymerase. (1445 aa)
rfc2Replication factor C (activator 1) 2. (361 aa)
rmi1RMI1, RecQ mediated genome instability 1, homolog (S. cerevisiae). (681 aa)
pold3Polymerase (DNA-directed), delta 3, accessory subunit. (447 aa)
I3KD07_ORENIDNA ligase. (594 aa)
blmBLM RecQ like helicase. (1407 aa)
ticrrTreslin_N domain-containing protein. (1868 aa)
I3KF05_ORENIUncharacterized protein. (510 aa)
mcm6DNA helicase; Belongs to the MCM family. (828 aa)
chaf1bChromatin assembly factor 1, subunit B. (600 aa)
polkPolymerase (DNA directed) kappa. (875 aa)
Slx4SLX4 structure-specific endonuclease subunit homolog (S. cerevisiae). (1016 aa)
I3KHG4_ORENISLX4 structure-specific endonuclease subunit homolog (S. cerevisiae). (252 aa)
sirt7Sirtuin 7. (406 aa)
rnaseh2aRibonuclease; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids; Belongs to the RNase HII family. (308 aa)
LOC102079736Uncharacterized protein. (966 aa)
NASPNuclear autoantigenic sperm protein. (519 aa)
rnaseh1Ribonuclease H1; Endonuclease that specifically degrades the RNA of RNA-DNA hybrids. (278 aa)
I3KRC2_ORENIUncharacterized protein. (407 aa)
RRM2Ribonucleotide reductase regulatory subunit M2. (406 aa)
pollPolymerase (DNA directed), lambda; Belongs to the DNA polymerase type-X family. (585 aa)
rfc4Replication factor C (activator 1) 4. (358 aa)
timelessTimeless circadian clock. (1245 aa)
Pold1DNA polymerase. (1105 aa)
recql5RecQ helicase-like 5. (1019 aa)
eme1Essential meiotic structure-specific endonuclease 1. (557 aa)
ENSONIP00000024927RecQ helicase-like 4. (958 aa)
I3KVR8_ORENIERCC4 domain-containing protein. (277 aa)
LOC100698471SET domain and mariner transposase fusion gene. (317 aa)
traipTRAF-interacting protein. (449 aa)
LOC100697672DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (756 aa)
ZNF830Zinc finger protein 830. (451 aa)
ENSONIP00000026881annotation not available (2493 aa)
ENSONIP00000027236annotation not available (1909 aa)
RPA1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (665 aa)
ssrp1FACT complex subunit SSRP1; Component of the FACT complex, a general chromatin factor that acts to reorganize nucleosomes. The FACT complex is involved in multiple processes that require DNA as a template such as mRNA elongation, DNA replication and DNA repair. During transcription elongation the FACT complex acts as a histone chaperone that both destabilizes and restores nucleosomal structure. It facilitates the passage of RNA polymerase II and transcription by promoting the dissociation of one histone H2A-H2B dimer from the nucleosome, then subsequently promotes the reestablishment o [...] (752 aa)
ENSONIP00000028394annotation not available (580 aa)
ENSONIP00000028447Polymerase (DNA directed) nu. (702 aa)
ENSONIP00000028865annotation not available (501 aa)
ttc38Tetratricopeptide repeat domain 38. (467 aa)
LOC100690838Nuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. (556 aa)
LOC109197824ATP-dependent DNA helicase PIF1. (843 aa)
ENSONIP00000030624annotation not available (1129 aa)
LOC100702321Probable flap endonuclease 1 homolog. (348 aa)
pold4DNA polymerase delta subunit 4. (107 aa)
LOC102079550Protein FAM111A-like. (623 aa)
lig3DNA ligase. (1037 aa)
LOC102075526Cyclin E2; Belongs to the cyclin family. (431 aa)
mcmbpMinichromosome maintenance complex binding protein. (635 aa)
ENSONIP00000032560annotation not available (691 aa)
LOC100709853Inhibitor of growth protein. (240 aa)
mcm2DNA helicase; Belongs to the MCM family. (899 aa)
ENSONIP00000032908annotation not available (478 aa)
ENSONIP00000033825Uncharacterized protein LOC109197015 isoform X1. (2105 aa)
ENSONIP00000033831annotation not available (1015 aa)
gins1GINS complex subunit 1 (Psf1 homolog). (196 aa)
ENSONIP00000034389annotation not available (2566 aa)
thoc1THO complex 1. (650 aa)
ENSONIP00000037861annotation not available (580 aa)
ENSONIP00000038064annotation not available (1796 aa)
LOC100706337WD_REPEATS_REGION domain-containing protein. (441 aa)
LOC100696561Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (822 aa)
ddx23DEAD (Asp-Glu-Ala-Asp) box polypeptide 23. (834 aa)
I3JAG7_ORENIUncharacterized protein. (403 aa)
ENSONIP00000040462Uncharacterized protein LOC109201108. (2534 aa)
LOC100694900Ribonucleoside-diphosphate reductase; Provides the precursors necessary for DNA synthesis. Catalyzes the biosynthesis of deoxyribonucleotides from the corresponding ribonucleotides. (813 aa)
rad51DNA repair protein RAD51 homolog; Plays an important role in homologous strand exchange, a key step in DNA repair through homologous recombination. Binds to single and double-stranded DNA and exhibits DNA-dependent ATPase activity. Catalyzes the recognition of homology and strand exchange between homologous DNA partners to form a joint molecule between a processed DNA break and the repair template. Binds to single-stranded DNA in an ATP-dependent manner to form nucleoprotein filaments which are essential for the homology search and strand exchange. Belongs to the RecA family. RAD51 sub [...] (343 aa)
LOC102082614Uncharacterized protein LOC102082614. (1038 aa)
ENSONIP00000042121ATP-dependent DNA helicase PIF1-like. (1901 aa)
polqPolymerase (DNA directed), theta. (2783 aa)
prim1DNA primase; Belongs to the eukaryotic-type primase small subunit family. (454 aa)
LOC109195818Uncharacterized protein LOC109195818 isoform X1. (927 aa)
ENSONIP00000042661annotation not available (545 aa)
ENSONIP00000043597annotation not available (486 aa)
cdc45CDC45 cell division cycle 45 homolog (S. cerevisiae). (574 aa)
ENSONIP00000044270annotation not available (2412 aa)
ENSONIP00000044374annotation not available (706 aa)
ENSONIP00000044851Regulator of telomere elongation helicase 1. (963 aa)
kinKin17 DNA and RNA binding protein. (394 aa)
ENSONIP00000045252annotation not available (1372 aa)
LOC109203110ATP-dependent DNA helicase PIF1-like. (587 aa)
ENSONIP00000045758Uncharacterized protein LOC109204253. (2454 aa)
ENSONIP00000046147annotation not available (479 aa)
Zpr1ZPR1 zinc finger. (155 aa)
dna2DNA replication helicase/nuclease 2. (1463 aa)
ENSONIP00000047167annotation not available (2123 aa)
mre11Double-strand break repair protein; Involved in DNA double-strand break repair (DSBR). Possesses single-strand endonuclease activity and double-strand-specific 3'-5' exonuclease activity. Also involved in meiotic DSB processing. (698 aa)
LOC100705387SAM domain and HD domain 1. (622 aa)
ENSONIP00000049246annotation not available (627 aa)
LOC100706185Deoxynucleoside triphosphate triphosphohydrolase SAMHD1-like. (607 aa)
ENSONIP00000050655annotation not available (1679 aa)
gmncUncharacterized protein. (427 aa)
LOC100709275Regulator of telomere elongation helicase 1; ATP-dependent DNA helicase implicated in telomere-length regulation, DNA repair and the maintenance of genomic stability. Acts as an anti-recombinase to counteract toxic recombination and limit crossover during meiosis. Regulates meiotic recombination and crossover homeostasis by physically dissociating strand invasion events and thereby promotes noncrossover repair by meiotic synthesis dependent strand annealing (SDSA) as well as disassembly of D loop recombination intermediates. Also disassembles T loops and prevents telomere fragility by [...] (1148 aa)
ENSONIP00000051286annotation not available (2102 aa)
ENSONIP00000051374annotation not available (886 aa)
ENSONIP00000052198Uncharacterized protein LOC102081688 isoform X1. (557 aa)
ENSONIP00000052505ATP-dependent DNA helicase PIF1-like. (547 aa)
LOC100694815Protein FAM111A. (639 aa)
ENSONIP00000052945annotation not available (1934 aa)
ENSONIP00000053191annotation not available (1246 aa)
ENSONIP00000053303annotation not available (1885 aa)
LOC100698382DNA topoisomerase I; Releases the supercoiling and torsional tension of DNA introduced during the DNA replication and transcription by transiently cleaving and rejoining one strand of the DNA duplex. Introduces a single-strand break via transesterification at the specific target site 5'-[CT]CCTTp site in duplex DNA. The scissile phosphodiester is attacked by the catalytic tyrosine of the enzyme, resulting in the formation of a DNA-(3'-phosphotyrosyl)-enzyme intermediate and the expulsion of a 5'-OH DNA strand. The free DNA strand then undergoes passage around the unbroken strand thus r [...] (720 aa)
ENSONIP00000054953ATP-dependent DNA helicase PIF1-like. (822 aa)
MCM7DNA replication licensing factor MCM7; Acts as component of the mcm2-7 complex (mcm complex) which is the putative replicative helicase essential for 'once per cell cycle' DNA replication initiation and elongation in eukaryotic cells. The active ATPase sites in the mcm2-7 ring are formed through the interaction surfaces of two neighboring subunits such that a critical structure of a conserved arginine finger motif is provided in trans relative to the ATP-binding site of the Walker A box of the adjacent subunit. The six ATPase active sites, however, are likely to contribute differential [...] (743 aa)
chtf8CTF8, chromosome transmission fidelity factor 8 homolog (S. cerevisiae). (143 aa)
NFIBNuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. (600 aa)
ENSONIP00000055662Uncharacterized protein LOC102076246 isoform X1. (2438 aa)
I3K3K4_ORENIHD domain-containing protein. (466 aa)
ENSONIP00000055981annotation not available (632 aa)
polgPolymerase (DNA directed), gamma. (1197 aa)
Orc4Origin recognition complex subunit 4; Component of the origin recognition complex (ORC) that binds origins of replication; Belongs to the ORC4 family. (454 aa)
ENSONIP00000056833annotation not available (951 aa)
ENSONIP00000057198annotation not available (674 aa)
ENSONIP00000057227annotation not available (626 aa)
LOC109202971Uncharacterized protein LOC109202971. (2037 aa)
mcm3DNA helicase; Belongs to the MCM family. (817 aa)
ENSONIP00000058387annotation not available (2512 aa)
cenpxCentromere protein X. (106 aa)
ENSONIP00000059673annotation not available (737 aa)
ENSONIP00000059694annotation not available (1912 aa)
ENSONIP00000060165Uncharacterized protein LOC109202816. (2438 aa)
ENSONIP00000060807annotation not available (422 aa)
ENSONIP00000060809annotation not available (951 aa)
I3IUD3_ORENIUncharacterized protein. (500 aa)
ENSONIP00000061011annotation not available (749 aa)
ENSONIP00000061033annotation not available (496 aa)
ENSONIP00000061534annotation not available (580 aa)
ENSONIP00000062846annotation not available (678 aa)
LOC102078113Uncharacterized protein LOC102078113. (554 aa)
ENSONIP00000063711Uncharacterized protein LOC102083162. (2552 aa)
PrimpolPrimase and polymerase (DNA-directed). (548 aa)
ENSONIP00000064007Uncharacterized protein LOC109199181. (551 aa)
LOC109196932Uncharacterized protein LOC109196932. (422 aa)
ddx11DEAD/H (Asp-Glu-Ala-Asp/His) box helicase 11. (895 aa)
LOC109195020Protein FAM111A-like. (500 aa)
ENSONIP00000065323annotation not available (2416 aa)
LOC109197015ATP-dependent DNA helicase PIF1. (727 aa)
pole3Polymerase (DNA directed), epsilon 3 (p17 subunit). (150 aa)
polg2DNA polymerase subunit gamma-2, mitochondrial isoform X1. (452 aa)
atrxATRX chromatin remodeler. (1852 aa)
ENSONIP00000066486Uncharacterized protein LOC112848182. (514 aa)
ENSONIP00000066709ATP-dependent DNA helicase PIF1. (881 aa)
ENSONIP00000066808annotation not available (123 aa)
ENSONIP00000066865annotation not available (1154 aa)
nficNuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. (542 aa)
ENSONIP00000067938annotation not available (2442 aa)
ENSONIP00000068385Uncharacterized protein LOC102079725. (2172 aa)
ENSONIP00000068657Deoxynucleoside triphosphate triphosphohydrolase SAMHD1-like. (98 aa)
ENSONIP00000069225annotation not available (745 aa)
ENSONIP00000069362annotation not available (578 aa)
ENSONIP00000069543annotation not available (970 aa)
ENSONIP00000069610annotation not available (360 aa)
rpa1Replication protein A subunit; As part of the heterotrimeric replication protein A complex (RPA/RP-A), binds and stabilizes single-stranded DNA intermediates, that form during DNA replication or upon DNA stress. It prevents their reannealing and in parallel, recruits and activates different proteins and complexes involved in DNA metabolism. Thereby, it plays an essential role both in DNA replication and the cellular response to DNA damage. (602 aa)
ENSONIP00000070103annotation not available (567 aa)
pcnaProliferating cell nuclear antigen; This protein is an auxiliary protein of DNA polymerase delta and is involved in the control of eukaryotic DNA replication by increasing the polymerase's processibility during elongation of the leading strand; Belongs to the PCNA family. (260 aa)
LOC100711479Retinoblastoma binding protein 4. (449 aa)
ENSONIP00000070673Uncharacterized protein LOC109197982. (2465 aa)
ENSONIP00000071466annotation not available (367 aa)
ENSONIP00000071769annotation not available (358 aa)
ENSONIP00000072466annotation not available (1291 aa)
ENSONIP00000072470Uncharacterized protein LOC109203143. (1793 aa)
ENSONIP00000072736Uncharacterized protein LOC109201765. (2715 aa)
tatdn1TatD DNase domain containing 1. (314 aa)
ENSONIP00000074207annotation not available (2468 aa)
LOC100701915Nuclear factor 1; Recognizes and binds the palindromic sequence 5'- TTGGCNNNNNGCCAA-3' present in viral and cellular promoters and in the origin of replication of adenovirus type 2. These proteins are individually capable of activating transcription and replication. (587 aa)
ENSONIP00000074985annotation not available (1985 aa)
pold2Polymerase (DNA directed), delta 2, regulatory subunit. (500 aa)
TipinTIMELESS-interacting protein; Plays an important role in the control of DNA replication and the maintenance of replication fork stability. Belongs to the CSM3 family. (381 aa)
polbDNA polymerase; DNA polymerase that functions in several pathways of DNA repair. Involved in base excision repair (BER) responsible for repair of lesions that give rise to abasic (AP) sites in DNA. Also contributes to DNA double-strand break repair by non-homologous end joining and homologous recombination. Has both template-dependent and template- independent (terminal transferase) DNA polymerase activities. Has also a 5'-deoxyribose-5-phosphate lyase (dRP lyase) activity. (336 aa)
LOC109200336ATP-dependent DNA helicase PIF1-like. (843 aa)
ENSONIP00000076308annotation not available (1933 aa)
recqlATP-dependent DNA helicase; Belongs to the helicase family. RecQ subfamily. (835 aa)
ENSONIP00000076896annotation not available (1372 aa)
rpa3Replication protein A3. (122 aa)
ENSONIP00000077100annotation not available (170 aa)
ENSONIP00000077188annotation not available (388 aa)
ENSONIP00000077558Uncharacterized protein LOC112841748. (514 aa)
ssbp1Single-stranded DNA binding protein 1. (147 aa)
gins4DNA replication complex GINS protein SLD5; The GINS complex plays an essential role in the initiation of DNA replication; Belongs to the GINS4/SLD5 family. (228 aa)
ENSONIP00000078769Uncharacterized protein LOC109200589 isoform X1. (1430 aa)
ENSONIP00000079047Uncharacterized protein LOC109197979 isoform X2. (2294 aa)
LOC109200249ATP-dependent DNA helicase PIF1-like. (711 aa)
LOC100695351Retinoblastoma binding protein 4, like. (479 aa)
noc3lNucleolar complex protein 3 homolog. (802 aa)
LOC102077867Uncharacterized protein. (671 aa)
pole2DNA polymerase epsilon subunit; Participates in DNA repair and in chromosomal DNA replication; Belongs to the DNA polymerase epsilon subunit B family. (539 aa)
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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