(11 nodes) Peptidyl-methionine modification network (Oreochromis niloticus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	naa60	N-acetyltransferase 15 (GCN5-related, putative). (242 aa)
	pdf	Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins; Belongs to the polypeptide deformylase family. (257 aa)
	naa35	N(alpha)-acetyltransferase 35, NatC auxiliary subunit. (724 aa)
	LOC100708634	Apolipoprotein A-Ib. (263 aa)
	METAP2	Methionine aminopeptidase 2; Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met- Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Belongs to the peptidase M24A family. Methionine aminopeptidase eukaryotic type 2 subfamily. (468 aa)
	naa20	N(alpha)-acetyltransferase 20, NatB catalytic subunit. (200 aa)
	naa25	N(alpha)-acetyltransferase 25, NatB auxiliary subunit. (971 aa)
	METAP2-2	Methionine aminopeptidase 2; Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met- Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Belongs to the peptidase M24A family. Methionine aminopeptidase eukaryotic type 2 subfamily. (500 aa)
	NAA15	N(alpha)-acetyltransferase 15, NatA auxiliary subunit. (1164 aa)
	naa30	N(alpha)-acetyltransferase 30, NatC catalytic subunit. (345 aa)
	LOC100695335	N(alpha)-acetyltransferase 15, NatA auxiliary subunit a. (882 aa)

Your Current Organism:

Oreochromis niloticus

NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC100695335	naa20	ENSONIP00000080109	ENSONIP00000060926	N(alpha)-acetyltransferase 15, NatA auxiliary subunit a.	N(alpha)-acetyltransferase 20, NatB catalytic subunit.	0.583
LOC100695335	naa25	ENSONIP00000080109	ENSONIP00000065420	N(alpha)-acetyltransferase 15, NatA auxiliary subunit a.	N(alpha)-acetyltransferase 25, NatB auxiliary subunit.	0.675
LOC100695335	naa30	ENSONIP00000080109	ENSONIP00000072077	N(alpha)-acetyltransferase 15, NatA auxiliary subunit a.	N(alpha)-acetyltransferase 30, NatC catalytic subunit.	0.568
LOC100695335	naa35	ENSONIP00000080109	ENSONIP00000018863	N(alpha)-acetyltransferase 15, NatA auxiliary subunit a.	N(alpha)-acetyltransferase 35, NatC auxiliary subunit.	0.571
LOC100695335	naa60	ENSONIP00000080109	ENSONIP00000008255	N(alpha)-acetyltransferase 15, NatA auxiliary subunit a.	N-acetyltransferase 15 (GCN5-related, putative).	0.828
METAP2	pdf	ENSONIP00000022491	ENSONIP00000013452	Methionine aminopeptidase 2; Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met- Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Belongs to the peptidase M24A family. Methionine aminopeptidase eukaryotic type 2 subfamily.	Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins; Belongs to the polypeptide deformylase family.	0.607
METAP2-2	pdf	ENSONIP00000067371	ENSONIP00000013452	Methionine aminopeptidase 2; Cotranslationally removes the N-terminal methionine from nascent proteins. The N-terminal methionine is often cleaved when the second residue in the primary sequence is small and uncharged (Met- Ala-, Cys, Gly, Pro, Ser, Thr, or Val). Belongs to the peptidase M24A family. Methionine aminopeptidase eukaryotic type 2 subfamily.	Peptide deformylase; Removes the formyl group from the N-terminal Met of newly synthesized proteins; Belongs to the polypeptide deformylase family.	0.607
NAA15	naa20	ENSONIP00000070212	ENSONIP00000060926	N(alpha)-acetyltransferase 15, NatA auxiliary subunit.	N(alpha)-acetyltransferase 20, NatB catalytic subunit.	0.583
NAA15	naa25	ENSONIP00000070212	ENSONIP00000065420	N(alpha)-acetyltransferase 15, NatA auxiliary subunit.	N(alpha)-acetyltransferase 25, NatB auxiliary subunit.	0.675
NAA15	naa30	ENSONIP00000070212	ENSONIP00000072077	N(alpha)-acetyltransferase 15, NatA auxiliary subunit.	N(alpha)-acetyltransferase 30, NatC catalytic subunit.	0.568
NAA15	naa35	ENSONIP00000070212	ENSONIP00000018863	N(alpha)-acetyltransferase 15, NatA auxiliary subunit.	N(alpha)-acetyltransferase 35, NatC auxiliary subunit.	0.571
NAA15	naa60	ENSONIP00000070212	ENSONIP00000008255	N(alpha)-acetyltransferase 15, NatA auxiliary subunit.	N-acetyltransferase 15 (GCN5-related, putative).	0.828
naa20	LOC100695335	ENSONIP00000060926	ENSONIP00000080109	N(alpha)-acetyltransferase 20, NatB catalytic subunit.	N(alpha)-acetyltransferase 15, NatA auxiliary subunit a.	0.583
naa20	NAA15	ENSONIP00000060926	ENSONIP00000070212	N(alpha)-acetyltransferase 20, NatB catalytic subunit.	N(alpha)-acetyltransferase 15, NatA auxiliary subunit.	0.583
naa20	naa25	ENSONIP00000060926	ENSONIP00000065420	N(alpha)-acetyltransferase 20, NatB catalytic subunit.	N(alpha)-acetyltransferase 25, NatB auxiliary subunit.	0.995
naa20	naa30	ENSONIP00000060926	ENSONIP00000072077	N(alpha)-acetyltransferase 20, NatB catalytic subunit.	N(alpha)-acetyltransferase 30, NatC catalytic subunit.	0.694
naa20	naa35	ENSONIP00000060926	ENSONIP00000018863	N(alpha)-acetyltransferase 20, NatB catalytic subunit.	N(alpha)-acetyltransferase 35, NatC auxiliary subunit.	0.688
naa20	naa60	ENSONIP00000060926	ENSONIP00000008255	N(alpha)-acetyltransferase 20, NatB catalytic subunit.	N-acetyltransferase 15 (GCN5-related, putative).	0.596
naa25	LOC100695335	ENSONIP00000065420	ENSONIP00000080109	N(alpha)-acetyltransferase 25, NatB auxiliary subunit.	N(alpha)-acetyltransferase 15, NatA auxiliary subunit a.	0.675
naa25	NAA15	ENSONIP00000065420	ENSONIP00000070212	N(alpha)-acetyltransferase 25, NatB auxiliary subunit.	N(alpha)-acetyltransferase 15, NatA auxiliary subunit.	0.675