(34 nodes) Deoxyribose phosphate metabolic process network (Oreochromis niloticus)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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second shell of interactors

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proteins of unknown 3D structure

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a 3D structure is known or predicted

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Predicted Interactions

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Your Input:
	ENSONIP00000061033	annotation not available (496 aa)
	I3K3K4_ORENI	HD domain-containing protein. (466 aa)
	nudt15	Nucleotide triphosphate diphosphatase NUDT15. (150 aa)
	ADK	Adenosine kinase. (386 aa)
	LOC100706185	Deoxynucleoside triphosphate triphosphohydrolase SAMHD1-like. (607 aa)
	LOC100705387	SAM domain and HD domain 1. (622 aa)
	I3JRP1_ORENI	Uncharacterized protein. (583 aa)
	I3KMU1_ORENI	Zgc:110540. (285 aa)
	ENSONIP00000043597	annotation not available (486 aa)
	ENSONIP00000042661	annotation not available (545 aa)
	I3JAG7_ORENI	Uncharacterized protein. (403 aa)
	nt5dc1	5'-nucleotidase domain containing 1. (459 aa)
	nudt18	Nudix (nucleoside diphosphate linked moiety X)-type motif 18; Belongs to the Nudix hydrolase family. (333 aa)
	LOC100693415	Adenosine kinase a. (374 aa)
	Dctpp1	dCTP pyrophosphatase 1; Hydrolyzes deoxynucleoside triphosphates (dNTPs) to the corresponding nucleoside monophosphates. Has a strong preference for dCTP and its analogs including 5-iodo-dCTP and 5-methyl-dCTP for which it may even have a higher efficiency. May protect DNA or RNA against the incorporation of these genotoxic nucleotide analogs through their catabolism. (151 aa)
	LOC100690403	Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. (311 aa)
	cmpk2	Cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial. (421 aa)
	tyms	Thymidylate synthetase. (325 aa)
	upp2	Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. (313 aa)
	dck	Deoxycytidine kinase. (263 aa)
	Gda	Guanine deaminase; Catalyzes the hydrolytic deamination of guanine, producing xanthine and ammonia; Belongs to the metallo-dependent hydrolases superfamily. ATZ/TRZ family. (539 aa)
	ENSONIP00000015699	Deoxynucleoside triphosphate triphosphohydrolase SAMHD1-like. (431 aa)
	LOC100705170	Deoxyguanosine kinase. (316 aa)
	dut	Deoxyuridine triphosphatase. (188 aa)
	ENSONIP00000016918	Adenylate kinase 9. (1392 aa)
	upb1	Ureidopropionase, beta. (384 aa)
	nt5c2	5'-nucleotidase, cytosolic IIb. (563 aa)
	dtymk	Deoxythymidylate kinase (thymidylate kinase). (249 aa)
	NT5M	5',3'-nucleotidase, mitochondrial. (229 aa)
	TYMP	Thymidine phosphorylase; Catalyzes the reversible phosphorolysis of thymidine. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family. (479 aa)
	LOC100698477	5'-nucleotidase, cytosolic II, like 1. (510 aa)
	ENSONIP00000071466	annotation not available (367 aa)
	I3K9K7_ORENI	Deoxyribose-phosphate aldolase (putative). (362 aa)
	ENSONIP00000068657	Deoxynucleoside triphosphate triphosphohydrolase SAMHD1-like. (98 aa)

Your Current Organism:

Oreochromis niloticus

NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ADK	ENSONIP00000016918	ENSONIP00000050544	ENSONIP00000016918	Adenosine kinase.	Adenylate kinase 9.	0.515
ADK	I3JRP1_ORENI	ENSONIP00000050544	ENSONIP00000047342	Adenosine kinase.	Uncharacterized protein.	0.668
ADK	I3K9K7_ORENI	ENSONIP00000050544	ENSONIP00000070120	Adenosine kinase.	Deoxyribose-phosphate aldolase (putative).	0.535
ADK	LOC100690403	ENSONIP00000050544	ENSONIP00000003859	Adenosine kinase.	Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.	0.677
ADK	LOC100693415	ENSONIP00000050544	ENSONIP00000034679	Adenosine kinase.	Adenosine kinase a.	0.901
ADK	LOC100698477	ENSONIP00000050544	ENSONIP00000076925	Adenosine kinase.	5'-nucleotidase, cytosolic II, like 1.	0.668
ADK	NT5M	ENSONIP00000050544	ENSONIP00000024724	Adenosine kinase.	5',3'-nucleotidase, mitochondrial.	0.661
ADK	TYMP	ENSONIP00000050544	ENSONIP00000077763	Adenosine kinase.	Thymidine phosphorylase; Catalyzes the reversible phosphorolysis of thymidine. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis. Belongs to the thymidine/pyrimidine-nucleoside phosphorylase family.	0.769
ADK	dtymk	ENSONIP00000050544	ENSONIP00000024266	Adenosine kinase.	Deoxythymidylate kinase (thymidylate kinase).	0.413
ADK	nt5c2	ENSONIP00000050544	ENSONIP00000023707	Adenosine kinase.	5'-nucleotidase, cytosolic IIb.	0.668
ADK	upp2	ENSONIP00000050544	ENSONIP00000011260	Adenosine kinase.	Uridine phosphorylase; Catalyzes the reversible phosphorylytic cleavage of uridine and deoxyuridine to uracil and ribose- or deoxyribose-1-phosphate. The produced molecules are then utilized as carbon and energy sources or in the rescue of pyrimidine bases for nucleotide synthesis.	0.677
Dctpp1	I3JRP1_ORENI	ENSONIP00000026584	ENSONIP00000047342	dCTP pyrophosphatase 1; Hydrolyzes deoxynucleoside triphosphates (dNTPs) to the corresponding nucleoside monophosphates. Has a strong preference for dCTP and its analogs including 5-iodo-dCTP and 5-methyl-dCTP for which it may even have a higher efficiency. May protect DNA or RNA against the incorporation of these genotoxic nucleotide analogs through their catabolism.	Uncharacterized protein.	0.900
Dctpp1	LOC100698477	ENSONIP00000026584	ENSONIP00000076925	dCTP pyrophosphatase 1; Hydrolyzes deoxynucleoside triphosphates (dNTPs) to the corresponding nucleoside monophosphates. Has a strong preference for dCTP and its analogs including 5-iodo-dCTP and 5-methyl-dCTP for which it may even have a higher efficiency. May protect DNA or RNA against the incorporation of these genotoxic nucleotide analogs through their catabolism.	5'-nucleotidase, cytosolic II, like 1.	0.900
Dctpp1	LOC100705170	ENSONIP00000026584	ENSONIP00000016787	dCTP pyrophosphatase 1; Hydrolyzes deoxynucleoside triphosphates (dNTPs) to the corresponding nucleoside monophosphates. Has a strong preference for dCTP and its analogs including 5-iodo-dCTP and 5-methyl-dCTP for which it may even have a higher efficiency. May protect DNA or RNA against the incorporation of these genotoxic nucleotide analogs through their catabolism.	Deoxyguanosine kinase.	0.912
Dctpp1	NT5M	ENSONIP00000026584	ENSONIP00000024724	dCTP pyrophosphatase 1; Hydrolyzes deoxynucleoside triphosphates (dNTPs) to the corresponding nucleoside monophosphates. Has a strong preference for dCTP and its analogs including 5-iodo-dCTP and 5-methyl-dCTP for which it may even have a higher efficiency. May protect DNA or RNA against the incorporation of these genotoxic nucleotide analogs through their catabolism.	5',3'-nucleotidase, mitochondrial.	0.902
Dctpp1	cmpk2	ENSONIP00000026584	ENSONIP00000004602	dCTP pyrophosphatase 1; Hydrolyzes deoxynucleoside triphosphates (dNTPs) to the corresponding nucleoside monophosphates. Has a strong preference for dCTP and its analogs including 5-iodo-dCTP and 5-methyl-dCTP for which it may even have a higher efficiency. May protect DNA or RNA against the incorporation of these genotoxic nucleotide analogs through their catabolism.	Cytidine monophosphate (UMP-CMP) kinase 2, mitochondrial.	0.900
Dctpp1	dck	ENSONIP00000026584	ENSONIP00000014035	dCTP pyrophosphatase 1; Hydrolyzes deoxynucleoside triphosphates (dNTPs) to the corresponding nucleoside monophosphates. Has a strong preference for dCTP and its analogs including 5-iodo-dCTP and 5-methyl-dCTP for which it may even have a higher efficiency. May protect DNA or RNA against the incorporation of these genotoxic nucleotide analogs through their catabolism.	Deoxycytidine kinase.	0.916
Dctpp1	nt5c2	ENSONIP00000026584	ENSONIP00000023707	dCTP pyrophosphatase 1; Hydrolyzes deoxynucleoside triphosphates (dNTPs) to the corresponding nucleoside monophosphates. Has a strong preference for dCTP and its analogs including 5-iodo-dCTP and 5-methyl-dCTP for which it may even have a higher efficiency. May protect DNA or RNA against the incorporation of these genotoxic nucleotide analogs through their catabolism.	5'-nucleotidase, cytosolic IIb.	0.900
ENSONIP00000016918	ADK	ENSONIP00000016918	ENSONIP00000050544	Adenylate kinase 9.	Adenosine kinase.	0.515
ENSONIP00000016918	LOC100693415	ENSONIP00000016918	ENSONIP00000034679	Adenylate kinase 9.	Adenosine kinase a.	0.515