(108 nodes) Synaptic vesicle membrane network (Oreochromis niloticus)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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textmining

co-expression

protein homology

Your Input:
	Lg7h16orf70	Si:dkey-102f14.5. (431 aa)
	syt1	Synaptotagmin Ia. (422 aa)
	slc18a1	Solute carrier family 18 member A1. (552 aa)
	I3IWC0_ORENI	Otoferlin b. (1769 aa)
	LAMP5	Lysosomal associated membrane protein family member 5. (265 aa)
	bcl2l1	BCL2 like 1. (232 aa)
	LOC100703802	Synaptophysin-like 2b. (236 aa)
	LOC100705376	Secretory carrier-associated membrane protein. (227 aa)
	LOC100695734	Secretory carrier-associated membrane protein. (241 aa)
	SV2A	Synaptic vesicle glycoprotein 2A. (737 aa)
	lrrk2	Leucine-rich repeat kinase 2. (2443 aa)
	LOC100705504	Synaptoporin. (303 aa)
	TMEM163	Transmembrane protein 163a. (289 aa)
	I3JA42_ORENI	Syntaxin 6; Belongs to the syntaxin family. (236 aa)
	UNC13A	Unc-13 homolog A. (1673 aa)
	wfs1	Wolfram syndrome 1b (wolframin). (977 aa)
	LOC100709259	Synaptogyrin. (224 aa)
	LOC100702345	Synaptotagmin IXa. (563 aa)
	I3JEN9_ORENI	Aa_trans domain-containing protein. (403 aa)
	Syt7	Synaptotagmin VIIb. (662 aa)
	I3JHR6_ORENI	Uncharacterized protein. (3776 aa)
	SYNDIG1	Synapse differentiation inducing 1. (270 aa)
	LOC100695033	Uncharacterized protein. (351 aa)
	LOC100702979	Synaptic vesicle glycoprotein 2A. (737 aa)
	DNM1L	Dynamin 1-like; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (721 aa)
	LOC100709626	Wolfram syndrome 1a (wolframin). (1062 aa)
	I3JRV2_ORENI	Synaptogyrin 1. (214 aa)
	LOC100703328	Si:dkey-16l2.16. (208 aa)
	SYN3	Synapsin III. (541 aa)
	I3K4V1_ORENI	Synaptic vesicle glycoprotein 2. (565 aa)
	syt12	Synaptotagmin XII. (429 aa)
	svop	SV2 related protein a. (552 aa)
	LOC100694538	SV2 related protein b. (544 aa)
	Atp6ap1	ATPase H+ transporting accessory protein 1a. (468 aa)
	LOC100710649	Synaptotagmin Ib. (409 aa)
	LOC100694717	Synaptic vesicle glycoprotein 2C. (736 aa)
	scamp1	Secretory carrier-associated membrane protein. (337 aa)
	ENSONIP00000019560	Synaptotagmin VIIa. (470 aa)
	syngr3	Synaptogyrin. (232 aa)
	LOC100706253	Synaptic vesicle glycoprotein 2Ca. (733 aa)
	clta	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (230 aa)
	I3KI81_ORENI	ATPase H+ transporting accessory protein 1b. (430 aa)
	I3KJH1_ORENI	Synaptophysin-like 1. (246 aa)
	LOC100700879	Synaptotagmin IIa. (431 aa)
	stx16	Syntaxin 16; Belongs to the syntaxin family. (317 aa)
	LOC100705449	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (154 aa)
	LOC100706499	Uncharacterized protein. (228 aa)
	LOC100704658	Synaptotagmin Vb. (422 aa)
	LOC100700270	BH4_2 domain-containing protein. (197 aa)
	LOC100694944	Synapsin I. (649 aa)
	LOC100694209	Synaptotagmin IXb. (527 aa)
	LOC100704986	Si:dkey-32e23.4; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (700 aa)
	SCAMP1	Secretory carrier-associated membrane protein. (347 aa)
	tmem163	Transmembrane protein 163. (317 aa)
	slc17a6	Solute carrier family 17 member 6. (601 aa)
	LOC100710042	Dystrobrevin binding protein 1b. (241 aa)
	cltb	Clathrin light chain; Clathrin is the major protein of the polyhedral coat of coated pits and vesicles; Belongs to the clathrin light chain family. (224 aa)
	cplx3	Complexin 3b. (156 aa)
	LOC100691355	Aa_trans domain-containing protein. (522 aa)
	LOC100692232	MFS domain-containing protein. (588 aa)
	UNC13C	Unc-13 homolog C. (2580 aa)
	mctp1	Multiple C2 domains, transmembrane 1a. (890 aa)
	syn2	Uncharacterized protein. (812 aa)
	ENSONIP00000040799	LOW QUALITY PROTEIN: V-type proton ATPase subunit B, brain isoform. (529 aa)
	LOC100700952	Synaptophysin a. (326 aa)
	fer1l6	Uncharacterized protein. (1851 aa)
	I3KJ10_ORENI	Dynamin 1-like; Belongs to the TRAFAC class dynamin-like GTPase superfamily. Dynamin/Fzo/YdjA family. (697 aa)
	LOC100700693	Multiple C2 domains, transmembrane 2b. (882 aa)
	I3KAQ4_ORENI	Bassoon (presynaptic cytomatrix protein) b. (3055 aa)
	I3K991_ORENI	Uncharacterized protein. (1429 aa)
	LOC100693903	Solute carrier family 17 member 7a. (591 aa)
	I3KKK6_ORENI	Synapsin IIa. (494 aa)
	I3JZN3_ORENI	Multiple C2 domains, transmembrane 1b. (786 aa)
	LOC100706230	Vesicle-associated membrane protein 1. (119 aa)
	LOC100693191	Solute carrier family 32 member 1. (526 aa)
	ENSONIP00000050976	Vesicle-associated membrane protein 2. (127 aa)
	LOC106096419	Solute carrier family 17 member 8. (585 aa)
	SLC17A6	Solute carrier family 17 member 6b. (609 aa)
	PRRT1	Proline-rich transmembrane protein 1. (92 aa)
	gabra2	Uncharacterized protein; Belongs to the ligand-gated ion channel (TC 1.A.9) family. (502 aa)
	otof	Otoferlin a. (2101 aa)
	I3JSC7_ORENI	Uncharacterized protein. (82 aa)
	LOC100706516	Synaptophysin-like 2a. (244 aa)
	LOC100706223	Zgc:92912. (101 aa)
	LOC100704291	MARVEL domain-containing protein. (237 aa)
	atp6ap2	ATPase H+ transporting accessory protein 2. (383 aa)
	borcs5	BLOC-1 related complex subunit 5. (197 aa)
	rab35	RAB35, member RAS oncogene family b. (201 aa)
	ENSONIP00000064480	Tumor suppressor candidate 5 homolog isoform X2. (225 aa)
	LOC100706152	Synaptogyrin. (253 aa)
	Slc18a2	Solute carrier family 18 member 2. (514 aa)
	UNC13B	Unc-13 homolog B. (4602 aa)
	LOC100699505	Uncharacterized protein. (430 aa)
	renbp	Renin binding protein. (448 aa)
	atp6v1f	V-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (119 aa)
	I3JVF4_ORENI	Uncharacterized protein. (1632 aa)
	LOC100707100	Uncharacterized protein. (257 aa)
	ATP6V0C	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells. (155 aa)
	LOC100689910	Multiple C2 domains, transmembrane 2a. (1058 aa)
	LOC100697206	Synaptic vesicle glycoprotein 2Ba. (714 aa)
	ENSONIP00000073079	Proline-rich transmembrane protein 1. (70 aa)
	SYNPR	Synaptoporin. (291 aa)
	ATP6V1B2	ATPase H+ transporting V1 subunit B2. (539 aa)
	I3IV58_ORENI	Syntaxin 10. (246 aa)
	syp	Synaptophysin b. (293 aa)
	gad2	Glutamate decarboxylase 2. (584 aa)
	LOC100694467	Uncharacterized protein. (250 aa)
	LOC100707465	MFS domain-containing protein. (669 aa)

Your Current Organism:

Oreochromis niloticus

NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ATP6V0C	ATP6V1B2	ENSONIP00000072138	ENSONIP00000073370	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	ATPase H+ transporting V1 subunit B2.	0.983
ATP6V0C	Atp6ap1	ENSONIP00000072138	ENSONIP00000018645	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	ATPase H+ transporting accessory protein 1a.	0.927
ATP6V0C	ENSONIP00000040799	ENSONIP00000072138	ENSONIP00000040799	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	LOW QUALITY PROTEIN: V-type proton ATPase subunit B, brain isoform.	0.983
ATP6V0C	I3KI81_ORENI	ENSONIP00000072138	ENSONIP00000020827	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	ATPase H+ transporting accessory protein 1b.	0.927
ATP6V0C	LOC100705449	ENSONIP00000072138	ENSONIP00000024425	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	0.900
ATP6V0C	atp6ap2	ENSONIP00000072138	ENSONIP00000063555	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	ATPase H+ transporting accessory protein 2.	0.915
ATP6V0C	atp6v1f	ENSONIP00000072138	ENSONIP00000070276	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	V-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	0.982
ATP6V1B2	ATP6V0C	ENSONIP00000073370	ENSONIP00000072138	ATPase H+ transporting V1 subunit B2.	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	0.983
ATP6V1B2	Atp6ap1	ENSONIP00000073370	ENSONIP00000018645	ATPase H+ transporting V1 subunit B2.	ATPase H+ transporting accessory protein 1a.	0.952
ATP6V1B2	ENSONIP00000040799	ENSONIP00000073370	ENSONIP00000040799	ATPase H+ transporting V1 subunit B2.	LOW QUALITY PROTEIN: V-type proton ATPase subunit B, brain isoform.	0.900
ATP6V1B2	I3KI81_ORENI	ENSONIP00000073370	ENSONIP00000020827	ATPase H+ transporting V1 subunit B2.	ATPase H+ transporting accessory protein 1b.	0.952
ATP6V1B2	LOC100705449	ENSONIP00000073370	ENSONIP00000024425	ATPase H+ transporting V1 subunit B2.	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	0.983
ATP6V1B2	atp6ap2	ENSONIP00000073370	ENSONIP00000063555	ATPase H+ transporting V1 subunit B2.	ATPase H+ transporting accessory protein 2.	0.939
ATP6V1B2	atp6v1f	ENSONIP00000073370	ENSONIP00000070276	ATPase H+ transporting V1 subunit B2.	V-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	0.997
Atp6ap1	ATP6V0C	ENSONIP00000018645	ENSONIP00000072138	ATPase H+ transporting accessory protein 1a.	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	0.927
Atp6ap1	ATP6V1B2	ENSONIP00000018645	ENSONIP00000073370	ATPase H+ transporting accessory protein 1a.	ATPase H+ transporting V1 subunit B2.	0.952
Atp6ap1	ENSONIP00000040799	ENSONIP00000018645	ENSONIP00000040799	ATPase H+ transporting accessory protein 1a.	LOW QUALITY PROTEIN: V-type proton ATPase subunit B, brain isoform.	0.952
Atp6ap1	LOC100705449	ENSONIP00000018645	ENSONIP00000024425	ATPase H+ transporting accessory protein 1a.	V-type proton ATPase proteolipid subunit; Proton-conducting pore forming subunit of the membrane integral V0 complex of vacuolar ATPase. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	0.927
Atp6ap1	atp6ap2	ENSONIP00000018645	ENSONIP00000063555	ATPase H+ transporting accessory protein 1a.	ATPase H+ transporting accessory protein 2.	0.966
Atp6ap1	atp6v1f	ENSONIP00000018645	ENSONIP00000070276	ATPase H+ transporting accessory protein 1a.	V-type proton ATPase subunit F; Subunit of the peripheral V1 complex of vacuolar ATPase essential for assembly or catalytic function. V-ATPase is responsible for acidifying a variety of intracellular compartments in eukaryotic cells.	0.944