(12 nodes) Cdc42 protein signal transduction network (Oreochromis niloticus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC100705957	Ras homolog family member Ub. (237 aa)
	I3JIW9_ORENI	Uncharacterized protein. (195 aa)
	LOC100699098	Ras homolog family member V. (281 aa)
	LOC100712562	Uncharacterized protein. (191 aa)
	LOC100696557	Uncharacterized protein. (191 aa)
	ENSONIP00000048570	annotation not available (155 aa)
	cdc42	Cell division cycle 42. (209 aa)
	I3KK64_ORENI	Uncharacterized protein. (278 aa)
	Shtn1	Shootin 1. (331 aa)
	LOC100705703	Uncharacterized protein. (190 aa)
	LOC100705444	Uncharacterized protein. (189 aa)
	I3J970_ORENI	Si:dkey-280e21.3. (594 aa)

Your Current Organism:

Oreochromis niloticus

NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica

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structured XML interaction data, according to the 'PSI-MI' data standard

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node degree of proteins in your network (given the current score cut-off)

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a flat-file format describing the coordinates and colors of nodes in the network

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MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

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a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
I3KK64_ORENI	cdc42	ENSONIP00000021509	ENSONIP00000037546	Uncharacterized protein.	Cell division cycle 42.	0.501
LOC100699098	cdc42	ENSONIP00000068677	ENSONIP00000037546	Ras homolog family member V.	Cell division cycle 42.	0.508
LOC100705957	cdc42	ENSONIP00000040714	ENSONIP00000037546	Ras homolog family member Ub.	Cell division cycle 42.	0.502
cdc42	I3KK64_ORENI	ENSONIP00000037546	ENSONIP00000021509	Cell division cycle 42.	Uncharacterized protein.	0.501
cdc42	LOC100699098	ENSONIP00000037546	ENSONIP00000068677	Cell division cycle 42.	Ras homolog family member V.	0.508
cdc42	LOC100705957	ENSONIP00000037546	ENSONIP00000040714	Cell division cycle 42.	Ras homolog family member Ub.	0.502