(17 nodes) SMN-Sm protein complex network (Oreochromis niloticus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	snrpd1	Small nuclear ribonucleoprotein Sm D1; Essential for pre-mRNA splicing. Implicated in the formation of stable, biologically active snRNP structures. Belongs to the snRNP core protein family. (110 aa)
	snrpd3	Small nuclear ribonucleoprotein Sm D3. (127 aa)
	strap	Serine/threonine kinase receptor associated protein. (366 aa)
	gemin4	Gem (nuclear organelle) associated protein 4. (1118 aa)
	gemin5	Gem (nuclear organelle) associated protein 5. (1466 aa)
	gemin2	Gem-associated protein 2; The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs; Belongs to the gemin-2 family. (264 aa)
	ENSONIP00000037472	annotation not available (173 aa)
	LOC100698882	Survival of motor neuron 1, telomeric. (282 aa)
	LOC102080291	Survival motor neuron protein isoform X1. (371 aa)
	snrpd2	Small nuclear ribonucleoprotein Sm D2. (118 aa)
	snrpb	Small nuclear ribonucleoprotein-associated protein. (256 aa)
	Snrpg	Small nuclear ribonucleoprotein G. (76 aa)
	Snrpf	Small nuclear ribonucleoprotein F. (85 aa)
	snrpe	Small nuclear ribonucleoprotein E. (92 aa)
	Gemin6	Gem (nuclear organelle) associated protein 6. (82 aa)
	ddx20	DEAD (Asp-Glu-Ala-Asp) box polypeptide 20; Belongs to the DEAD box helicase family. (827 aa)
	gemin8	Gem (nuclear organelle) associated protein 8. (209 aa)

Your Current Organism:

Oreochromis niloticus

NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSONIP00000037472	Gemin6	ENSONIP00000037472	ENSONIP00000072963	annotation not available	Gem (nuclear organelle) associated protein 6.	0.665
ENSONIP00000037472	LOC100698882	ENSONIP00000037472	ENSONIP00000040981	annotation not available	Survival of motor neuron 1, telomeric.	0.819
ENSONIP00000037472	LOC102080291	ENSONIP00000037472	ENSONIP00000045201	annotation not available	Survival motor neuron protein isoform X1.	0.819
ENSONIP00000037472	Snrpf	ENSONIP00000037472	ENSONIP00000068044	annotation not available	Small nuclear ribonucleoprotein F.	0.610
ENSONIP00000037472	Snrpg	ENSONIP00000037472	ENSONIP00000064463	annotation not available	Small nuclear ribonucleoprotein G.	0.484
ENSONIP00000037472	ddx20	ENSONIP00000037472	ENSONIP00000073632	annotation not available	DEAD (Asp-Glu-Ala-Asp) box polypeptide 20; Belongs to the DEAD box helicase family.	0.941
ENSONIP00000037472	gemin5	ENSONIP00000037472	ENSONIP00000020708	annotation not available	Gem (nuclear organelle) associated protein 5.	0.533
ENSONIP00000037472	gemin8	ENSONIP00000037472	ENSONIP00000075753	annotation not available	Gem (nuclear organelle) associated protein 8.	0.841
ENSONIP00000037472	snrpd1	ENSONIP00000037472	ENSONIP00000068638	annotation not available	Small nuclear ribonucleoprotein Sm D1; Essential for pre-mRNA splicing. Implicated in the formation of stable, biologically active snRNP structures. Belongs to the snRNP core protein family.	0.421
ENSONIP00000037472	snrpd2	ENSONIP00000037472	ENSONIP00000054582	annotation not available	Small nuclear ribonucleoprotein Sm D2.	0.604
ENSONIP00000037472	snrpd3	ENSONIP00000037472	ENSONIP00000004821	annotation not available	Small nuclear ribonucleoprotein Sm D3.	0.585
ENSONIP00000037472	snrpe	ENSONIP00000037472	ENSONIP00000072391	annotation not available	Small nuclear ribonucleoprotein E.	0.566
ENSONIP00000037472	strap	ENSONIP00000037472	ENSONIP00000016060	annotation not available	Serine/threonine kinase receptor associated protein.	0.613
Gemin6	ENSONIP00000037472	ENSONIP00000072963	ENSONIP00000037472	Gem (nuclear organelle) associated protein 6.	annotation not available	0.665
Gemin6	LOC100698882	ENSONIP00000072963	ENSONIP00000040981	Gem (nuclear organelle) associated protein 6.	Survival of motor neuron 1, telomeric.	0.701
Gemin6	LOC102080291	ENSONIP00000072963	ENSONIP00000045201	Gem (nuclear organelle) associated protein 6.	Survival motor neuron protein isoform X1.	0.664
Gemin6	Snrpf	ENSONIP00000072963	ENSONIP00000068044	Gem (nuclear organelle) associated protein 6.	Small nuclear ribonucleoprotein F.	0.637
Gemin6	Snrpg	ENSONIP00000072963	ENSONIP00000064463	Gem (nuclear organelle) associated protein 6.	Small nuclear ribonucleoprotein G.	0.632
Gemin6	ddx20	ENSONIP00000072963	ENSONIP00000073632	Gem (nuclear organelle) associated protein 6.	DEAD (Asp-Glu-Ala-Asp) box polypeptide 20; Belongs to the DEAD box helicase family.	0.972
Gemin6	gemin2	ENSONIP00000072963	ENSONIP00000032436	Gem (nuclear organelle) associated protein 6.	Gem-associated protein 2; The SMN complex plays a catalyst role in the assembly of small nuclear ribonucleoproteins (snRNPs), the building blocks of the spliceosome. Thereby, plays an important role in the splicing of cellular pre-mRNAs; Belongs to the gemin-2 family.	0.773