(67 nodes) Histone lysine methylation network (Oreochromis niloticus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	paxip1	PAX interacting (with transcription-activation domain) protein 1. (1095 aa)
	ctr9	CTR9 homolog, Paf1/RNA polymerase II complex component. (1174 aa)
	I3J275_ORENI	Nuclear transcription factor Y, gamma. (375 aa)
	I3KWS1_ORENI	CXXC finger protein 1b. (560 aa)
	LOC100708974	SET and MYND domain containing 1b. (535 aa)
	LOC100691614	Lysine methyltransferase 5C. (2039 aa)
	LOC100691830	Uncharacterized protein. (133 aa)
	rbbp5	Retinoblastoma binding protein 5. (570 aa)
	LOC100705541	CXXC finger protein 1a. (622 aa)
	EZH1	Enhancer of zeste 1 polycomb repressive complex 2 subunit. (768 aa)
	pno1	Partner of NOB1 homolog. (252 aa)
	Setd4	SET domain containing 4. (456 aa)
	n6amt1	N-6 adenine-specific DNA methyltransferase 1. (218 aa)
	kmt2b	Lysine (K)-specific methyltransferase 2Bb. (3861 aa)
	setd2	SET domain containing 2, histone lysine methyltransferase. (2602 aa)
	twf2	WD repeat domain 82. (581 aa)
	KMT2A	Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. TRX/MLL subfamily. (4124 aa)
	ash1l	Uncharacterized protein. (2029 aa)
	setdb1	SET domain bifurcated histone lysine methyltransferase 1b. (1230 aa)
	LOC100709898	Uncharacterized protein. (904 aa)
	LOC100702714	Uncharacterized protein. (236 aa)
	creg1	Uncharacterized protein. (644 aa)
	SMYD1	SET and MYND domain containing 1. (493 aa)
	I3JTS7_ORENI	Lysine (K)-specific methyltransferase 2Cb. (417 aa)
	I3JV04_ORENI	Translocase of outer mitochondrial membrane 20. (1232 aa)
	pagr1	PAXIP1 associated glutamate-rich protein 1. (277 aa)
	ash2l	Ash2 like, histone lysine methyltransferase complex subunit. (592 aa)
	setd7	SET domain containing 7, histone lysine methyltransferase. (361 aa)
	suv39h1	Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily. (411 aa)
	kmt2d	Lysine (K)-specific methyltransferase 2D. (5041 aa)
	wdr5	WD repeat domain 5. (333 aa)
	LOC100693266	Uncharacterized protein. (440 aa)
	ehmt2	Euchromatic histone-lysine N-methyltransferase 2. (1208 aa)
	LOC100692647	SET domain containing 1B, histone lysine methyltransferase a. (1811 aa)
	Kmt5b	Lysine methyltransferase 5B. (865 aa)
	LOC100698697	SET and MYND domain containing 2a. (435 aa)
	smyd3	SET and MYND domain containing 3. (439 aa)
	ezh2	Enhancer of zeste 2 polycomb repressive complex 2 subunit. (763 aa)
	kiaa2013	Si:dkeyp-104h9.5. (620 aa)
	LOC100709494	Twinfilin actin-binding protein 2b. (599 aa)
	LOC100707110	Ash1 (absent, small, or homeotic)-like (Drosophila). (2966 aa)
	LOC100689867	Histone-lysine N-methyltransferase 2B. (3138 aa)
	LOC100698471	SET domain and mariner transposase fusion gene. (317 aa)
	setd3	Protein-histidine N-methyltransferase. (657 aa)
	gcc1	GRIP and coiled-coil domain containing 1. (759 aa)
	men1	Multiple endocrine neoplasia I. (629 aa)
	kmt5a	Lysine methyltransferase 5Aa. (333 aa)
	dot1l	Histone-lysine N-methyltransferase, H3 lysine-79 specific. (1610 aa)
	arid4a	AT rich interactive domain 4A (RBP1-like). (1391 aa)
	setd5	SET domain containing 5. (1521 aa)
	ENSONIP00000042957	Uncharacterized protein LOC109194549. (997 aa)
	wdr61	WD repeat domain 61. (305 aa)
	setbp1	SET-binding protein. (1374 aa)
	pwp1	PWP1 homolog, endonuclein. (510 aa)
	ogt	O-linked N-acetylglucosamine (GlcNAc) transferase, tandem duplicate 1. (1073 aa)
	setd1a	[histone H3]-lysine4 N-trimethyltransferase SETD1. (2262 aa)
	Nfya	Nuclear transcription factor Y subunit alpha isoform X6. (303 aa)
	LOC100698146	Zinc finger protein 335. (1586 aa)
	I3JNL0_ORENI	Uncharacterized protein. (842 aa)
	ENSONIP00000056910	LOW QUALITY PROTEIN: histone-lysine N-methyltransferase 2C. (3073 aa)
	ehmt1	Euchromatic histone-lysine N-methyltransferase 1b. (1325 aa)
	I3K397_ORENI	Nuclear receptor binding SET domain protein 2. (1109 aa)
	ENSONIP00000058389	[histone H4]-lysine20 N-methyltransferase SETD8. (248 aa)
	ncoa6	Nuclear receptor coactivator 6. (2385 aa)
	prdm5	Zinc finger protein. (630 aa)
	rtf1	RTF1 homolog, Paf1/RNA polymerase II complex component. (671 aa)
	smyd5	SMYD family member 5. (427 aa)

Your Current Organism:

Oreochromis niloticus

NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica

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a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSONIP00000042957	ash2l	ENSONIP00000042957	ENSONIP00000014499	Uncharacterized protein LOC109194549.	Ash2 like, histone lysine methyltransferase complex subunit.	0.541
ENSONIP00000042957	rbbp5	ENSONIP00000042957	ENSONIP00000000597	Uncharacterized protein LOC109194549.	Retinoblastoma binding protein 5.	0.623
ENSONIP00000056910	I3JTS7_ORENI	ENSONIP00000056910	ENSONIP00000012272	LOW QUALITY PROTEIN: histone-lysine N-methyltransferase 2C.	Lysine (K)-specific methyltransferase 2Cb.	0.875
ENSONIP00000056910	KMT2A	ENSONIP00000056910	ENSONIP00000007849	LOW QUALITY PROTEIN: histone-lysine N-methyltransferase 2C.	Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. TRX/MLL subfamily.	0.577
ENSONIP00000056910	LOC100689867	ENSONIP00000056910	ENSONIP00000024873	LOW QUALITY PROTEIN: histone-lysine N-methyltransferase 2C.	Histone-lysine N-methyltransferase 2B.	0.577
ENSONIP00000056910	LOC100692647	ENSONIP00000056910	ENSONIP00000017473	LOW QUALITY PROTEIN: histone-lysine N-methyltransferase 2C.	SET domain containing 1B, histone lysine methyltransferase a.	0.643
ENSONIP00000056910	LOC100693266	ENSONIP00000056910	ENSONIP00000016993	LOW QUALITY PROTEIN: histone-lysine N-methyltransferase 2C.	Uncharacterized protein.	0.407
ENSONIP00000056910	LOC100698697	ENSONIP00000056910	ENSONIP00000021543	LOW QUALITY PROTEIN: histone-lysine N-methyltransferase 2C.	SET and MYND domain containing 2a.	0.407
ENSONIP00000056910	ash2l	ENSONIP00000056910	ENSONIP00000014499	LOW QUALITY PROTEIN: histone-lysine N-methyltransferase 2C.	Ash2 like, histone lysine methyltransferase complex subunit.	0.938
ENSONIP00000056910	gcc1	ENSONIP00000056910	ENSONIP00000030149	LOW QUALITY PROTEIN: histone-lysine N-methyltransferase 2C.	GRIP and coiled-coil domain containing 1.	0.437
ENSONIP00000056910	kmt2b	ENSONIP00000056910	ENSONIP00000003450	LOW QUALITY PROTEIN: histone-lysine N-methyltransferase 2C.	Lysine (K)-specific methyltransferase 2Bb.	0.577
ENSONIP00000056910	men1	ENSONIP00000056910	ENSONIP00000030525	LOW QUALITY PROTEIN: histone-lysine N-methyltransferase 2C.	Multiple endocrine neoplasia I.	0.469
ENSONIP00000056910	ncoa6	ENSONIP00000056910	ENSONIP00000059368	LOW QUALITY PROTEIN: histone-lysine N-methyltransferase 2C.	Nuclear receptor coactivator 6.	0.437
ENSONIP00000056910	pagr1	ENSONIP00000056910	ENSONIP00000014434	LOW QUALITY PROTEIN: histone-lysine N-methyltransferase 2C.	PAXIP1 associated glutamate-rich protein 1.	0.581
ENSONIP00000056910	paxip1	ENSONIP00000056910	ENSONIP00000012183	LOW QUALITY PROTEIN: histone-lysine N-methyltransferase 2C.	PAX interacting (with transcription-activation domain) protein 1.	0.533
ENSONIP00000056910	pno1	ENSONIP00000056910	ENSONIP00000001545	LOW QUALITY PROTEIN: histone-lysine N-methyltransferase 2C.	Partner of NOB1 homolog.	0.437
ENSONIP00000056910	rbbp5	ENSONIP00000056910	ENSONIP00000000597	LOW QUALITY PROTEIN: histone-lysine N-methyltransferase 2C.	Retinoblastoma binding protein 5.	0.929
ENSONIP00000056910	setd1a	ENSONIP00000056910	ENSONIP00000048030	LOW QUALITY PROTEIN: histone-lysine N-methyltransferase 2C.	[histone H3]-lysine4 N-trimethyltransferase SETD1.	0.643
ENSONIP00000056910	setd3	ENSONIP00000056910	ENSONIP00000029556	LOW QUALITY PROTEIN: histone-lysine N-methyltransferase 2C.	Protein-histidine N-methyltransferase.	0.620
ENSONIP00000056910	setd7	ENSONIP00000056910	ENSONIP00000014561	LOW QUALITY PROTEIN: histone-lysine N-methyltransferase 2C.	SET domain containing 7, histone lysine methyltransferase.	0.465