(21 nodes) mRNA cis splicing, via spliceosome network (Oreochromis niloticus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	Wbp11	WW domain binding protein 11. (694 aa)
	LOC100701998	Si:ch211-114c17.1. (724 aa)
	sfswap	Splicing factor SWAP. (952 aa)
	prpf39	PRP39 pre-mRNA processing factor 39 homolog (yeast). (778 aa)
	dnajc8	DnaJ (Hsp40) homolog, subfamily C, member 8. (250 aa)
	Dcps	Decapping enzyme, scavenger. (333 aa)
	Wbp4	Uncharacterized protein. (398 aa)
	SART1	Spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP. (769 aa)
	ENSONIP00000031680	Nuclear cap-binding protein subunit 2-like. (120 aa)
	ENSONIP00000045775	annotation not available (61 aa)
	ENSONIP00000046810	Nuclear cap-binding protein subunit 2-like. (91 aa)
	prpf4b	Pre-mRNA processing factor 4Bb. (1020 aa)
	PSIP1	PC4 and SFRS1 interacting protein 1. (383 aa)
	cwc15	CWC15 spliceosome associated protein homolog. (237 aa)
	LOC100702413	Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...] (164 aa)
	ENSONIP00000075314	annotation not available (120 aa)
	rbm22	RNA binding motif protein 22. (427 aa)
	rbm17	RNA binding motif protein 17. (418 aa)
	sf3a1	Splicing factor 3a, subunit 1. (785 aa)
	cactin	Cactin. (875 aa)
	prpf40a	PRP40 pre-mRNA processing factor 40 homolog A. (879 aa)

Your Current Organism:

Oreochromis niloticus

NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSONIP00000031680	ENSONIP00000046810	ENSONIP00000031680	ENSONIP00000046810	Nuclear cap-binding protein subunit 2-like.	Nuclear cap-binding protein subunit 2-like.	0.901
ENSONIP00000031680	LOC100701998	ENSONIP00000031680	ENSONIP00000006635	Nuclear cap-binding protein subunit 2-like.	Si:ch211-114c17.1.	0.577
ENSONIP00000031680	LOC100702413	ENSONIP00000031680	ENSONIP00000071076	Nuclear cap-binding protein subunit 2-like.	Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...]	0.903
ENSONIP00000031680	SART1	ENSONIP00000031680	ENSONIP00000026585	Nuclear cap-binding protein subunit 2-like.	Spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP.	0.542
ENSONIP00000031680	Wbp11	ENSONIP00000031680	ENSONIP00000010474	Nuclear cap-binding protein subunit 2-like.	WW domain binding protein 11.	0.519
ENSONIP00000031680	cwc15	ENSONIP00000031680	ENSONIP00000064198	Nuclear cap-binding protein subunit 2-like.	CWC15 spliceosome associated protein homolog.	0.641
ENSONIP00000031680	prpf39	ENSONIP00000031680	ENSONIP00000001090	Nuclear cap-binding protein subunit 2-like.	PRP39 pre-mRNA processing factor 39 homolog (yeast).	0.577
ENSONIP00000031680	rbm22	ENSONIP00000031680	ENSONIP00000016411	Nuclear cap-binding protein subunit 2-like.	RNA binding motif protein 22.	0.638
ENSONIP00000031680	sf3a1	ENSONIP00000031680	ENSONIP00000013643	Nuclear cap-binding protein subunit 2-like.	Splicing factor 3a, subunit 1.	0.767
ENSONIP00000046810	ENSONIP00000031680	ENSONIP00000046810	ENSONIP00000031680	Nuclear cap-binding protein subunit 2-like.	Nuclear cap-binding protein subunit 2-like.	0.901
ENSONIP00000046810	LOC100701998	ENSONIP00000046810	ENSONIP00000006635	Nuclear cap-binding protein subunit 2-like.	Si:ch211-114c17.1.	0.577
ENSONIP00000046810	LOC100702413	ENSONIP00000046810	ENSONIP00000071076	Nuclear cap-binding protein subunit 2-like.	Nuclear cap-binding protein subunit 2; Component of the cap-binding complex (CBC), which binds co- transcriptionally to the 5' cap of pre-mRNAs and is involved in various processes such as pre-mRNA splicing, translation regulation, nonsense- mediated mRNA decay, RNA-mediated gene silencing (RNAi) by microRNAs (miRNAs) and mRNA export. The CBC complex is involved in mRNA export from the nucleus, leading to the recruitment of the mRNA export machinery to the 5' end of mRNA and to mRNA export in a 5' to 3' direction through the nuclear pore. The CBC complex is also involved in mediating U [...]	0.902
ENSONIP00000046810	SART1	ENSONIP00000046810	ENSONIP00000026585	Nuclear cap-binding protein subunit 2-like.	Spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP.	0.542
ENSONIP00000046810	Wbp11	ENSONIP00000046810	ENSONIP00000010474	Nuclear cap-binding protein subunit 2-like.	WW domain binding protein 11.	0.519
ENSONIP00000046810	cwc15	ENSONIP00000046810	ENSONIP00000064198	Nuclear cap-binding protein subunit 2-like.	CWC15 spliceosome associated protein homolog.	0.641
ENSONIP00000046810	prpf39	ENSONIP00000046810	ENSONIP00000001090	Nuclear cap-binding protein subunit 2-like.	PRP39 pre-mRNA processing factor 39 homolog (yeast).	0.577
ENSONIP00000046810	rbm22	ENSONIP00000046810	ENSONIP00000016411	Nuclear cap-binding protein subunit 2-like.	RNA binding motif protein 22.	0.638
ENSONIP00000046810	sf3a1	ENSONIP00000046810	ENSONIP00000013643	Nuclear cap-binding protein subunit 2-like.	Splicing factor 3a, subunit 1.	0.767
ENSONIP00000075314	LOC100701998	ENSONIP00000075314	ENSONIP00000006635	annotation not available	Si:ch211-114c17.1.	0.577
ENSONIP00000075314	SART1	ENSONIP00000075314	ENSONIP00000026585	annotation not available	Spliceosome associated factor 1, recruiter of U4/U6.U5 tri-snRNP.	0.542