(56 nodes) Regulation of embryonic development network (Oreochromis niloticus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	racgap1	Rac GTPase activating protein 1. (648 aa)
	ENSONIP00000059519	annotation not available (135 aa)
	tdg	Thymine DNA glycosylase, tandem duplicate 1. (449 aa)
	Phldb1	Pleckstrin homology-like domain, family B, member 1b. (1638 aa)
	LOC100697424	Pleckstrin homology-like domain, family B, member 1a. (1211 aa)
	bag6	BCL2 associated athanogene 6. (1228 aa)
	LOC100693428	Pleckstrin homology-like domain family B member 2 isoform X1. (1469 aa)
	dr1	Down-regulator of transcription 1. (176 aa)
	ino80e	INO80 complex subunit E. (237 aa)
	tfpt	TCF3 fusion partner isoform X3. (220 aa)
	Zzz3	Zinc finger, ZZ-type containing 3. (1111 aa)
	LOC100710169	RAB14, member RAS oncogene family. (215 aa)
	mcrs1	Microspherule protein 1. (467 aa)
	phldb3	PH domain-containing protein. (417 aa)
	I3KER7_ORENI	Thymine DNA glycosylase, tandem duplicate 2. (410 aa)
	LOC100694839	BCL2 associated athanogene 6, like. (826 aa)
	LOC100706032	Uncharacterized protein. (336 aa)
	ENSONIP00000058229	Large proline-rich protein BAG6 isoform X1. (171 aa)
	Rbm19	RNA binding motif protein 19. (1009 aa)
	tada2a	Transcriptional adapter. (460 aa)
	I3JC34_ORENI	Pleckstrin homology-like domain, family B, member 2a. (979 aa)
	ccsap	Centriole, cilia and spindle-associated protein b. (281 aa)
	LOC100699984	Peptidase S72 domain-containing protein. (909 aa)
	dag1	Dystroglycan 1. (903 aa)
	I3KSL0_ORENI	Si:ch1073-416j23.1. (397 aa)
	sgf29	SAGA complex associated factor 29. (290 aa)
	nfe2l2	Nuclear factor, erythroid 2-like 2a. (597 aa)
	ino80d	INO80 complex subunit Da. (1005 aa)
	LOC100693354	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (392 aa)
	Rspo3	R-spondin 3. (332 aa)
	kat14	Lysine acetyltransferase 14. (791 aa)
	LAMA2	Laminin subunit alpha 2. (3002 aa)
	trip12	Thyroid hormone receptor interactor 12. (2065 aa)
	nfrkb	Nuclear factor related to kappaB binding protein. (1274 aa)
	Hesx1	Homeobox domain-containing protein. (138 aa)
	dhx36	DEAH (Asp-Glu-Ala-His) box polypeptide 36. (1064 aa)
	noct	Nocturnin a. (360 aa)
	wdpcp	WD repeat containing planar cell polarity effector. (740 aa)
	mbip	MAP3K12 binding inhibitory protein 1. (336 aa)
	ino80	INO80 complex ATPase subunit. (1573 aa)
	LOC100697822	Uncharacterized protein. (215 aa)
	LOC100704408	Uncharacterized protein. (634 aa)
	rack1	Guanine nucleotide-binding protein subunit beta-2-like 1; Involved in the recruitment, assembly and/or regulation of a variety of signaling molecules. Interacts with a wide variety of proteins and plays a role in many cellular processes. Required for VANGL2 membrane localization, inhibits Wnt signaling and regulates cellular polarization and oriented cell division during gastrulation (By similarity); Belongs to the WD repeat G protein beta family. Ribosomal protein RACK1 subfamily. (323 aa)
	gper1	G protein-coupled estrogen receptor 1; Belongs to the G-protein coupled receptor 1 family. (362 aa)
	lama4	Laminin, alpha 4. (1873 aa)
	ENSONIP00000015004	LOW QUALITY PROTEIN: protein O-glucosyltransferase 1-like. (363 aa)
	POGLUT1	Protein O-glucosyltransferase 1. (364 aa)
	wnt2b	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family. (410 aa)
	LAMA3	Laminin subunit alpha 3. (2691 aa)
	uchl5	Ubiquitin carboxyl-terminal hydrolase. (332 aa)
	lhx1	LIM homeobox 1a. (407 aa)
	cactin	Cactin. (875 aa)
	sfrp2	Secreted frizzled-related protein 2. (295 aa)
	yeats2	YEATS domain containing 2. (1436 aa)
	LYPD6	LY6/PLAUR domain containing 6. (175 aa)
	lama1	Laminin, alpha 1. (2770 aa)

Your Current Organism:

Oreochromis niloticus

NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSONIP00000015004	POGLUT1	ENSONIP00000015004	ENSONIP00000015003	LOW QUALITY PROTEIN: protein O-glucosyltransferase 1-like.	Protein O-glucosyltransferase 1.	0.900
ENSONIP00000058229	LOC100694839	ENSONIP00000058229	ENSONIP00000020093	Large proline-rich protein BAG6 isoform X1.	BCL2 associated athanogene 6, like.	0.898
LAMA2	LOC100699984	ENSONIP00000007306	ENSONIP00000021921	Laminin subunit alpha 2.	Peptidase S72 domain-containing protein.	0.683
LAMA2	dag1	ENSONIP00000007306	ENSONIP00000023354	Laminin subunit alpha 2.	Dystroglycan 1.	0.683
LAMA3	LOC100699984	ENSONIP00000075913	ENSONIP00000021921	Laminin subunit alpha 3.	Peptidase S72 domain-containing protein.	0.448
LAMA3	dag1	ENSONIP00000075913	ENSONIP00000023354	Laminin subunit alpha 3.	Dystroglycan 1.	0.448
LOC100693354	LOC100706032	ENSONIP00000029114	ENSONIP00000021103	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Uncharacterized protein.	0.830
LOC100693354	sfrp2	ENSONIP00000029114	ENSONIP00000012827	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	Secreted frizzled-related protein 2.	0.830
LOC100694839	ENSONIP00000058229	ENSONIP00000020093	ENSONIP00000058229	BCL2 associated athanogene 6, like.	Large proline-rich protein BAG6 isoform X1.	0.898
LOC100699984	LAMA2	ENSONIP00000021921	ENSONIP00000007306	Peptidase S72 domain-containing protein.	Laminin subunit alpha 2.	0.683
LOC100699984	LAMA3	ENSONIP00000021921	ENSONIP00000075913	Peptidase S72 domain-containing protein.	Laminin subunit alpha 3.	0.448
LOC100699984	dag1	ENSONIP00000021921	ENSONIP00000023354	Peptidase S72 domain-containing protein.	Dystroglycan 1.	0.902
LOC100699984	lama4	ENSONIP00000021921	ENSONIP00000027809	Peptidase S72 domain-containing protein.	Laminin, alpha 4.	0.798
LOC100706032	LOC100693354	ENSONIP00000021103	ENSONIP00000029114	Uncharacterized protein.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.830
LOC100706032	wnt2b	ENSONIP00000021103	ENSONIP00000014493	Uncharacterized protein.	Protein Wnt; Ligand for members of the frizzled family of seven transmembrane receptors; Belongs to the Wnt family.	0.830
POGLUT1	ENSONIP00000015004	ENSONIP00000015003	ENSONIP00000015004	Protein O-glucosyltransferase 1.	LOW QUALITY PROTEIN: protein O-glucosyltransferase 1-like.	0.900
Zzz3	dr1	ENSONIP00000045891	ENSONIP00000035723	Zinc finger, ZZ-type containing 3.	Down-regulator of transcription 1.	0.804
Zzz3	kat14	ENSONIP00000045891	ENSONIP00000008648	Zinc finger, ZZ-type containing 3.	Lysine acetyltransferase 14.	0.966
Zzz3	mbip	ENSONIP00000045891	ENSONIP00000001263	Zinc finger, ZZ-type containing 3.	MAP3K12 binding inhibitory protein 1.	0.888
Zzz3	sgf29	ENSONIP00000045891	ENSONIP00000011784	Zinc finger, ZZ-type containing 3.	SAGA complex associated factor 29.	0.996