STRINGSTRING
gata5 gata5 sav1 sav1 LOC100699623 LOC100699623 ENSONIP00000000898 ENSONIP00000000898 pdgfc pdgfc EZH1 EZH1 LOC100534578 LOC100534578 LOC100691047 LOC100691047 id2 id2 clmp clmp LOC100690458 LOC100690458 yap1 yap1 LOC100697082 LOC100697082 shh shh hlx hlx foxf2 foxf2 tbx20 tbx20 prdm1 prdm1 I3JI49_ORENI I3JI49_ORENI LOC100703294 LOC100703294 hhex hhex vps52 vps52 LOC100710660 LOC100710660 gata6 gata6 LOC100700789 LOC100700789 sfrp2 sfrp2 LOC100700059 LOC100700059 il6st il6st smo smo I3K111_ORENI I3K111_ORENI hnf1b hnf1b LOC100704452 LOC100704452 mixl1 mixl1 gata4 gata4 LOC100700828 LOC100700828 epg5 epg5 LOC100699860 LOC100699860 pdx1 pdx1 LOC102078253 LOC102078253 LOC109194164 LOC109194164 nipbl nipbl chd8 chd8 agr2 agr2 LOC100692689 LOC100692689 LOC100712046 LOC100712046 LOC100706032 LOC100706032 I3KLB2_ORENI I3KLB2_ORENI LOC100690331 LOC100690331 ezh2 ezh2 Pkd1 Pkd1 LOC100705614 LOC100705614 prkci prkci LOC100695616 LOC100695616 CLDN18 CLDN18 utp25 utp25 MYOCD MYOCD med24 med24 pkdcc pkdcc LOC100699737 LOC100699737 ascl1 ascl1 cobl cobl LOC100698910 LOC100698910 LOC100693567 LOC100693567 Mb Mb I3JXB9_ORENI I3JXB9_ORENI LOC100709152 LOC100709152 pitx2 pitx2 tgfb2 tgfb2 tp63 tp63 LOC100704989 LOC100704989 mib1 mib1 LOC100702133 LOC100702133 ENSONIP00000040678 ENSONIP00000040678 ENSONIP00000040932 ENSONIP00000040932 msc msc tcf21 tcf21 nkx3-2 nkx3-2 myod1 myod1 ruvbl2 ruvbl2 nkx2-3 nkx2-3 tp73 tp73 ENSONIP00000058376 ENSONIP00000058376 wdr55 wdr55 VANGL2 VANGL2 Fgfr2 Fgfr2 Invs Invs hand2 hand2 LOC100707239 LOC100707239 LOC100691479 LOC100691479 rnpc3 rnpc3 rb1 rb1 I3KFM8_ORENI I3KFM8_ORENI myf5 myf5
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
gata5GATA binding protein 5. (383 aa)
sav1Salvador family WW domain containing protein 1. (407 aa)
LOC100699623IKAROS family zinc finger 5. (423 aa)
ENSONIP00000000898Abelson helper integration site 1. (777 aa)
pdgfcPlatelet derived growth factor c; Belongs to the PDGF/VEGF growth factor family. (364 aa)
EZH1Enhancer of zeste 1 polycomb repressive complex 2 subunit. (768 aa)
LOC100534578Tumor necrosis factor b (TNF superfamily, member 2). (247 aa)
LOC100691047WT1 interacting protein. (711 aa)
id2Inhibitor of DNA binding 2a. (136 aa)
clmpUncharacterized protein. (391 aa)
LOC100690458Transforming growth factor beta; Belongs to the TGF-beta family. (419 aa)
yap1Yes-associated protein 1. (455 aa)
LOC100697082Potassium voltage-gated channel, KQT-like subfamily, member 1.1; Belongs to the potassium channel family. (693 aa)
shhHedgehog protein; Intercellular signal essential for a variety of patterning events during development. (415 aa)
hlxH2.0-like homeo box 1 (Drosophila). (379 aa)
foxf2Forkhead box F2b. (382 aa)
tbx20T-box transcription factor 20. (440 aa)
prdm1PR domain containing 1a, with ZNF domain. (848 aa)
I3JI49_ORENIKruppel-like factor 5b. (385 aa)
LOC100703294Uncharacterized protein. (677 aa)
hhexHomeobox domain-containing protein. (289 aa)
vps52VPS52 subunit of GARP complex. (703 aa)
LOC100710660T-box transcription factor Ta. (463 aa)
gata6GATA binding protein 6. (534 aa)
LOC100700789Forkhead box F2a. (381 aa)
sfrp2Secreted frizzled-related protein 2. (295 aa)
LOC100700059Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (244 aa)
il6stUncharacterized protein. (893 aa)
smoSmoothened, frizzled class receptor; Belongs to the G-protein coupled receptor Fz/Smo family. (825 aa)
I3K111_ORENIHomeobox domain-containing protein. (272 aa)
hnf1bHNF1 homeobox Ba. (576 aa)
LOC100704452Kruppel-like factor 5 like. (439 aa)
mixl1Mix paired-like homeobox. (341 aa)
gata4GATA binding protein 4. (389 aa)
LOC100700828PR domain containing 1b, with ZNF domain. (621 aa)
epg5Ectopic P-granules autophagy protein 5 homolog (C. elegans). (2588 aa)
LOC100699860Nipped-B protein. (2689 aa)
pdx1Pancreatic and duodenal homeobox 1. (255 aa)
LOC102078253G_PROTEIN_RECEP_F1_2 domain-containing protein. (428 aa)
LOC109194164Uncharacterized protein. (784 aa)
nipblNipped-B protein. (2541 aa)
chd8Chromodomain-helicase-DNA-binding protein 8; DNA helicase that acts as a chromatin remodeling factor and regulates transcription. Acts as a transcription repressor by remodeling chromatin structure and recruiting histone H1 to target genes. Suppresses p53/TP53-mediated apoptosis by recruiting histone H1 and preventing p53/TP53 transactivation activity. Acts as a negative regulator of Wnt signaling pathway by regulating beta-catenin (CTNNB1) activity. Negatively regulates CTNNB1-targeted gene expression by being recruited specifically to the promoter regions of several CTNNB1 responsive [...] (2621 aa)
agr2Anterior gradient 2. (167 aa)
LOC100692689IKAROS family zinc finger 5. (417 aa)
LOC100712046Endothelin receptor type Bb; Belongs to the G-protein coupled receptor 1 family. (492 aa)
LOC100706032Uncharacterized protein. (336 aa)
I3KLB2_ORENIUncharacterized protein. (200 aa)
LOC100690331G_PROTEIN_RECEP_F1_2 domain-containing protein; Belongs to the G-protein coupled receptor 1 family. (428 aa)
ezh2Enhancer of zeste 2 polycomb repressive complex 2 subunit. (763 aa)
Pkd1Polycystic kidney disease 1a. (4572 aa)
LOC100705614NK3 homeobox 3. (259 aa)
prkciProtein kinase C; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. PKC subfamily. (588 aa)
LOC100695616Vang-like protein. (526 aa)
CLDN18Claudin; Plays a major role in tight junction-specific obliteration of the intercellular space, through calcium-independent cell-adhesion activity; Belongs to the claudin family. (255 aa)
utp25UTP25 small subunit processor component. (648 aa)
MYOCDMyocardin. (1054 aa)
med24Mediator complex subunit 24. (989 aa)
pkdccProtein kinase domain containing, cytoplasmic b. (575 aa)
LOC100699737G protein-coupled receptor 22b. (432 aa)
ascl1Achaete-scute family bHLH transcription factor 1a. (188 aa)
coblCordon-bleu WH2 repeat protein. (1572 aa)
LOC100698910Uncharacterized protein. (256 aa)
LOC100693567Forkhead box protein I2-like. (384 aa)
MbMyoglobin; Serves as a reserve supply of oxygen and facilitates the movement of oxygen within muscles. (198 aa)
I3JXB9_ORENIForkhead box L1. (411 aa)
LOC100709152Uncharacterized protein; Belongs to the potassium channel family. (696 aa)
pitx2Homeobox protein. (313 aa)
tgfb2Transforming growth factor beta; Belongs to the TGF-beta family. (422 aa)
tp63Tumor protein 63 (p63); Acts as a sequence specific DNA binding transcriptional activator or repressor. The isoforms contain a varying set of transactivation and auto-regulating transactivation inhibiting domains thus showing an isoform specific activity. May be required in conjunction with TP73/p73 for initiation of p53/TP53 dependent apoptosis in response to genotoxic insults and the presence of activated oncogenes. (691 aa)
LOC100704989Endothelin receptor Ba; Belongs to the G-protein coupled receptor 1 family. (429 aa)
mib1Mindbomb E3 ubiquitin protein ligase 1. (1040 aa)
LOC100702133Forkhead box A3. (466 aa)
ENSONIP00000040678annotation not available (245 aa)
ENSONIP00000040932T-box transcription factor TBX1-A. (290 aa)
mscMusculin (activated B-cell factor-1). (166 aa)
tcf21Basic helix-loop-helix protein 21. (174 aa)
nkx3-2NK3 homeobox 2. (265 aa)
myod1Myogenic factor. (300 aa)
ruvbl2RuvB-like helicase; Proposed core component of the chromatin remodeling Ino80 complex which exhibits DNA- and nucleosome-activated ATPase activity and catalyzes ATP-dependent nucleosome sliding. (467 aa)
nkx2-3NK2 homeobox 3. (344 aa)
tp73Cellular tumor antigen p53; Acts as a tumor suppressor in many tumor types; induces growth arrest or apoptosis depending on the physiological circumstances and cell type. Involved in cell cycle regulation as a trans-activator that acts to negatively regulate cell division by controlling a set of genes required for this process. One of the activated genes is an inhibitor of cyclin-dependent kinases. Apoptosis induction seems to be mediated either by stimulation of BAX and FAS antigen expression, or by repression of Bcl-2 expression; Belongs to the p53 family. (674 aa)
ENSONIP00000058376annotation not available (135 aa)
wdr55WD repeat-containing protein 55; Nucleolar protein that acts as a modulator of rRNA synthesis. Plays a central role during organogenesis. Belongs to the WD repeat WDR55 family. (419 aa)
VANGL2Vang-like protein. (525 aa)
Fgfr2Fibroblast growth factor receptor. (865 aa)
InvsInversin. (671 aa)
hand2Heart and neural crest derivatives expressed 2. (245 aa)
LOC100707239Progesterone immunomodulatory binding factor 1. (509 aa)
LOC100691479Homeobox domain-containing protein. (360 aa)
rnpc3RNA-binding region (RNP1, RRM) containing 3. (602 aa)
rb1Retinoblastoma 1. (919 aa)
I3KFM8_ORENIT-box transcription factor 1. (434 aa)
myf5Myogenic factor. (241 aa)
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
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