(15 nodes) Negative regulation of smooth muscle cell differentiation network (Oreochromis niloticus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	nfatc2	Nuclear factor of activated T cells 2a. (896 aa)
	LOC100709722	EGF-like domain-containing protein. (133 aa)
	nfatc3	Nuclear factor of activated T cells 3a. (1113 aa)
	mecp2	Methyl CpG binding protein 2. (1076 aa)
	dnmt1	DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family. (1510 aa)
	pdcd4	Programmed cell death 4b. (475 aa)
	PRDM6	PR/SET domain 6. (657 aa)
	I3JWU8_ORENI	Nuclear factor of activated T cells 3b. (883 aa)
	LOC100707172	Platelet-derived growth factor beta polypeptide b; Belongs to the PDGF/VEGF growth factor family. (612 aa)
	NFATC1	Nuclear factor of activated T cells 1. (939 aa)
	rbpms2	RNA binding protein, mRNA processing factor 2b. (269 aa)
	LOC100712331	Platelet-derived growth factor beta polypeptide a; Belongs to the PDGF/VEGF growth factor family. (545 aa)
	LOC100708189	Programmed cell death 4a. (465 aa)
	LOC100711301	Nuclear factor of activated T cells 1. (928 aa)
	ccdc142	Coiled-coil domain-containing protein 142 isoform X1. (1132 aa)

Your Current Organism:

Oreochromis niloticus

NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
I3JWU8_ORENI	LOC100711301	ENSONIP00000013343	ENSONIP00000055290	Nuclear factor of activated T cells 3b.	Nuclear factor of activated T cells 1.	0.481
I3JWU8_ORENI	NFATC1	ENSONIP00000013343	ENSONIP00000009217	Nuclear factor of activated T cells 3b.	Nuclear factor of activated T cells 1.	0.479
I3JWU8_ORENI	nfatc2	ENSONIP00000013343	ENSONIP00000044656	Nuclear factor of activated T cells 3b.	Nuclear factor of activated T cells 2a.	0.564
LOC100711301	I3JWU8_ORENI	ENSONIP00000055290	ENSONIP00000013343	Nuclear factor of activated T cells 1.	Nuclear factor of activated T cells 3b.	0.481
LOC100711301	NFATC1	ENSONIP00000055290	ENSONIP00000009217	Nuclear factor of activated T cells 1.	Nuclear factor of activated T cells 1.	0.902
LOC100711301	nfatc2	ENSONIP00000055290	ENSONIP00000044656	Nuclear factor of activated T cells 1.	Nuclear factor of activated T cells 2a.	0.680
LOC100711301	nfatc3	ENSONIP00000055290	ENSONIP00000031086	Nuclear factor of activated T cells 1.	Nuclear factor of activated T cells 3a.	0.479
LOC100712331	nfatc3	ENSONIP00000071817	ENSONIP00000031086	Platelet-derived growth factor beta polypeptide a; Belongs to the PDGF/VEGF growth factor family.	Nuclear factor of activated T cells 3a.	0.480
NFATC1	I3JWU8_ORENI	ENSONIP00000009217	ENSONIP00000013343	Nuclear factor of activated T cells 1.	Nuclear factor of activated T cells 3b.	0.479
NFATC1	LOC100711301	ENSONIP00000009217	ENSONIP00000055290	Nuclear factor of activated T cells 1.	Nuclear factor of activated T cells 1.	0.902
NFATC1	nfatc2	ENSONIP00000009217	ENSONIP00000044656	Nuclear factor of activated T cells 1.	Nuclear factor of activated T cells 2a.	0.679
NFATC1	nfatc3	ENSONIP00000009217	ENSONIP00000031086	Nuclear factor of activated T cells 1.	Nuclear factor of activated T cells 3a.	0.474
dnmt1	mecp2	ENSONIP00000029113	ENSONIP00000029287	DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	Methyl CpG binding protein 2.	0.721
mecp2	dnmt1	ENSONIP00000029287	ENSONIP00000029113	Methyl CpG binding protein 2.	DNA (cytosine-5)-methyltransferase; Belongs to the class I-like SAM-binding methyltransferase superfamily. C5-methyltransferase family.	0.721
nfatc2	I3JWU8_ORENI	ENSONIP00000044656	ENSONIP00000013343	Nuclear factor of activated T cells 2a.	Nuclear factor of activated T cells 3b.	0.564
nfatc2	LOC100711301	ENSONIP00000044656	ENSONIP00000055290	Nuclear factor of activated T cells 2a.	Nuclear factor of activated T cells 1.	0.680
nfatc2	NFATC1	ENSONIP00000044656	ENSONIP00000009217	Nuclear factor of activated T cells 2a.	Nuclear factor of activated T cells 1.	0.679
nfatc2	nfatc3	ENSONIP00000044656	ENSONIP00000031086	Nuclear factor of activated T cells 2a.	Nuclear factor of activated T cells 3a.	0.563
nfatc3	LOC100711301	ENSONIP00000031086	ENSONIP00000055290	Nuclear factor of activated T cells 3a.	Nuclear factor of activated T cells 1.	0.479
nfatc3	LOC100712331	ENSONIP00000031086	ENSONIP00000071817	Nuclear factor of activated T cells 3a.	Platelet-derived growth factor beta polypeptide a; Belongs to the PDGF/VEGF growth factor family.	0.480