36 items (Oreochromis niloticus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

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co-expression

protein homology

Your Input:
	adnp	Activity-dependent neuroprotector homeobox b. (1058 aa)
	atm	Non-specific serine/threonine protein kinase. (3095 aa)
	tnfrsf21	Tumor necrosis factor receptor superfamily, member 21. (683 aa)
	casp9	Caspase 9, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family. (431 aa)
	tmtc4	Transmembrane O-mannosyltransferase targeting cadherins 4. (741 aa)
	cln8	CLN8 transmembrane ER and ERGIC protein. (270 aa)
	cdk5	Cyclin-dependent kinase 5; Belongs to the protein kinase superfamily. (292 aa)
	dnajc5g	DnaJ (Hsp40) homolog, subfamily C, member 5 gamma a. (221 aa)
	spg11	SPG11 vesicle trafficking associated, spatacsin. (2428 aa)
	lig4	DNA ligase. (910 aa)
	aifm1	Apoptosis inducing factor mitochondrion associated 1. (650 aa)
	Nf1	Neurofibromin 1b. (2742 aa)
	LOC100694240	DnaJ (Hsp40) homolog, subfamily C, member 5ab. (196 aa)
	LOC100691596	DnaJ (Hsp40) homolog, subfamily C, member 5aa. (199 aa)
	rapsn	Receptor-associated protein of the synapse, 43kD. (423 aa)
	LOC100690683	Diablo, IAP-binding mitochondrial protein a. (237 aa)
	I3KTN0_ORENI	Citron Rho-interacting kinase; Plays a role in cytokinesis. Displays serine/threonine protein kinase activity; Belongs to the protein kinase superfamily. AGC Ser/Thr protein kinase family. (2006 aa)
	ppargc1a	PPARG coactivator 1 alpha. (1284 aa)
	LOC100698117	Family with sequence similarity 162 member A. (165 aa)
	LOC100701346	Diablo, IAP-binding mitochondrial protein a. (264 aa)
	gapdh	Glyceraldehyde-3-phosphate dehydrogenase. (359 aa)
	NCSTN	Nicastrin. (697 aa)
	LOC100696823	Glyceraldehyde-3-phosphate dehydrogenase. (361 aa)
	I3KG87_ORENI	Citron rho-interacting serine/threonine kinase b. (1683 aa)
	I3JGQ5_ORENI	Uncharacterized protein. (1603 aa)
	Nfatc4	Nuclear factor of activated T-cells, cytoplasmic 4 isoform X1. (974 aa)
	siah1	E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates. (341 aa)
	sncb	Beta-synuclein; Belongs to the synuclein family. (134 aa)
	LOC109194153	J domain-containing protein. (233 aa)
	Fadd	Uncharacterized protein. (209 aa)
	I3IWI9_ORENI	Nerve growth factor receptor a (TNFR superfamily, member 16). (427 aa)
	rb1	Retinoblastoma 1. (919 aa)
	LOC100692494	DnaJ homolog subfamily C member 5 isoform X2. (204 aa)
	LOC106097998	Uncharacterized protein. (200 aa)
	ENSONIP00000078800	annotation not available (168 aa)
	Pigt	Phosphatidylinositol glycan anchor biosynthesis, class T. (670 aa)

Your Current Organism:

Oreochromis niloticus

NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
ENSONIP00000078800	LOC100696823	ENSONIP00000078800	ENSONIP00000059789	annotation not available	Glyceraldehyde-3-phosphate dehydrogenase.	0.458
ENSONIP00000078800	gapdh	ENSONIP00000078800	ENSONIP00000033368	annotation not available	Glyceraldehyde-3-phosphate dehydrogenase.	0.458
Fadd	casp9	ENSONIP00000071989	ENSONIP00000008378	Uncharacterized protein.	Caspase 9, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.	0.688
Fadd	tnfrsf21	ENSONIP00000071989	ENSONIP00000008131	Uncharacterized protein.	Tumor necrosis factor receptor superfamily, member 21.	0.524
I3IWI9_ORENI	NCSTN	ENSONIP00000074675	ENSONIP00000035581	Nerve growth factor receptor a (TNFR superfamily, member 16).	Nicastrin.	0.468
I3JGQ5_ORENI	casp9	ENSONIP00000063781	ENSONIP00000008378	Uncharacterized protein.	Caspase 9, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.	0.534
LOC100690683	LOC100701346	ENSONIP00000021241	ENSONIP00000028757	Diablo, IAP-binding mitochondrial protein a.	Diablo, IAP-binding mitochondrial protein a.	0.901
LOC100690683	LOC106097998	ENSONIP00000021241	ENSONIP00000076958	Diablo, IAP-binding mitochondrial protein a.	Uncharacterized protein.	0.452
LOC100690683	aifm1	ENSONIP00000021241	ENSONIP00000016196	Diablo, IAP-binding mitochondrial protein a.	Apoptosis inducing factor mitochondrion associated 1.	0.470
LOC100690683	casp9	ENSONIP00000021241	ENSONIP00000008378	Diablo, IAP-binding mitochondrial protein a.	Caspase 9, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.	0.725
LOC100696823	ENSONIP00000078800	ENSONIP00000059789	ENSONIP00000078800	Glyceraldehyde-3-phosphate dehydrogenase.	annotation not available	0.458
LOC100696823	siah1	ENSONIP00000059789	ENSONIP00000067676	Glyceraldehyde-3-phosphate dehydrogenase.	E3 ubiquitin-protein ligase; E3 ubiquitin-protein ligase that mediates ubiquitination and subsequent proteasomal degradation of target proteins. E3 ubiquitin ligases accept ubiquitin from an E2 ubiquitin-conjugating enzyme in the form of a thioester and then directly transfers the ubiquitin to targeted substrates.	0.458
LOC100701346	LOC100690683	ENSONIP00000028757	ENSONIP00000021241	Diablo, IAP-binding mitochondrial protein a.	Diablo, IAP-binding mitochondrial protein a.	0.901
LOC100701346	LOC106097998	ENSONIP00000028757	ENSONIP00000076958	Diablo, IAP-binding mitochondrial protein a.	Uncharacterized protein.	0.452
LOC100701346	aifm1	ENSONIP00000028757	ENSONIP00000016196	Diablo, IAP-binding mitochondrial protein a.	Apoptosis inducing factor mitochondrion associated 1.	0.470
LOC100701346	casp9	ENSONIP00000028757	ENSONIP00000008378	Diablo, IAP-binding mitochondrial protein a.	Caspase 9, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.	0.725
LOC106097998	LOC100690683	ENSONIP00000076958	ENSONIP00000021241	Uncharacterized protein.	Diablo, IAP-binding mitochondrial protein a.	0.452
LOC106097998	LOC100701346	ENSONIP00000076958	ENSONIP00000028757	Uncharacterized protein.	Diablo, IAP-binding mitochondrial protein a.	0.452
LOC106097998	aifm1	ENSONIP00000076958	ENSONIP00000016196	Uncharacterized protein.	Apoptosis inducing factor mitochondrion associated 1.	0.923
LOC106097998	casp9	ENSONIP00000076958	ENSONIP00000008378	Uncharacterized protein.	Caspase 9, apoptosis-related cysteine peptidase; Belongs to the peptidase C14A family.	0.517