31 items (Oreochromis niloticus) - STRING interaction network

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	glrx5	Glutaredoxin 5 homolog (S. cerevisiae). (156 aa)
	LOC100691852	Cytidine monophospho-N-acetylneuraminic acid hydroxylase. (608 aa)
	LOC100696766	Apoptosis inducing factor mitochondria associated 4. (538 aa)
	ENSONIP00000010953	Apoptosis inducing factor mitochondria associated 5. (444 aa)
	xdh	Xanthine dehydrogenase. (1355 aa)
	UQCRFS1	Cytochrome b-c1 complex subunit Rieske, mitochondrial; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. (135 aa)
	LOC100707594	Cytochrome b-c1 complex subunit Rieske, mitochondrial; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis. (273 aa)
	glrx2	Glutaredoxin 2. (172 aa)
	FDX1	Ferredoxin 1. (147 aa)
	aox1	Aldehyde oxidase 6. (1332 aa)
	LOC100702604	Zgc:92275. (452 aa)
	Iscu	Iron-sulfur cluster assembly enzyme; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. (167 aa)
	LOC100705178	Iron-sulfur cluster assembly enzyme b; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins. (165 aa)
	LOC100698621	Uncharacterized protein; Belongs to the complex I 75 kDa subunit family. (745 aa)
	fdx2	Ferredoxin 2. (196 aa)
	rfesd	Rieske (Fe-S) domain containing. (159 aa)
	LOC100706616	Uncharacterized protein; Belongs to the BolA/IbaG family. (112 aa)
	LOC100692561	CDGSH iron-sulfur domain-containing protein 3, mitochondrial. (132 aa)
	Fxn	Frataxin, mitochondrial. (122 aa)
	LOC100696819	Rieske domain-containing protein. (173 aa)
	fech	Ferrochelatase; Catalyzes the ferrous insertion into protoporphyrin IX. (403 aa)
	LOC100712084	Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (351 aa)
	ndufv2	NADH:ubiquinone oxidoreductase core subunit V2. (236 aa)
	aifm3	Apoptosis inducing factor mitochondria associated 3. (614 aa)
	NDUFS1	NADH:ubiquinone oxidoreductase core subunit S1; Belongs to the complex I 75 kDa subunit family. (759 aa)
	Cisd3	CDGSH iron-sulfur domain-containing protein 3, mitochondrial. (119 aa)
	isca2	Iron-sulfur cluster assembly 2. (176 aa)
	isca1	Iron-sulfur cluster assembly 1 homolog, mitochondrial. (129 aa)
	ciapin1	Anamorsin; Component of the cytosolic iron-sulfur (Fe-S) protein assembly (CIA) machinery required for the maturation of extramitochondrial Fe-S proteins. Part of an electron transfer chain functioning in an early step of cytosolic Fe-S biogenesis, facilitating the de novo assembly of a [4Fe-4S] cluster on the scaffold complex NUBP1-NUBP2. Electrons are transferred to CIAPIN1 from NADPH via the FAD- and FMN-containing protein NDOR1. NDOR1-CIAPIN1 are also required for the assembly of the diferric tyrosyl radical cofactor of ribonucleotide reductase (RNR), probably by providing electron [...] (313 aa)
	cisd2	CDGSH iron sulfur domain 2. (215 aa)
	SDHB	Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q). (282 aa)

Your Current Organism:

Oreochromis niloticus

NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of protiens in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Cisd3	Fxn	ENSONIP00000060534	ENSONIP00000029150	CDGSH iron-sulfur domain-containing protein 3, mitochondrial.	Frataxin, mitochondrial.	0.543
Cisd3	cisd2	ENSONIP00000060534	ENSONIP00000072313	CDGSH iron-sulfur domain-containing protein 3, mitochondrial.	CDGSH iron sulfur domain 2.	0.551
ENSONIP00000010953	FDX1	ENSONIP00000010953	ENSONIP00000015113	Apoptosis inducing factor mitochondria associated 5.	Ferredoxin 1.	0.738
ENSONIP00000010953	LOC100698621	ENSONIP00000010953	ENSONIP00000019162	Apoptosis inducing factor mitochondria associated 5.	Uncharacterized protein; Belongs to the complex I 75 kDa subunit family.	0.403
ENSONIP00000010953	LOC100702604	ENSONIP00000010953	ENSONIP00000016346	Apoptosis inducing factor mitochondria associated 5.	Zgc:92275.	0.686
ENSONIP00000010953	LOC100712084	ENSONIP00000010953	ENSONIP00000051312	Apoptosis inducing factor mitochondria associated 5.	Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).	0.404
ENSONIP00000010953	NDUFS1	ENSONIP00000010953	ENSONIP00000056489	Apoptosis inducing factor mitochondria associated 5.	NADH:ubiquinone oxidoreductase core subunit S1; Belongs to the complex I 75 kDa subunit family.	0.403
ENSONIP00000010953	SDHB	ENSONIP00000010953	ENSONIP00000079398	Apoptosis inducing factor mitochondria associated 5.	Succinate dehydrogenase [ubiquinone] iron-sulfur subunit, mitochondrial; Iron-sulfur protein (IP) subunit of succinate dehydrogenase (SDH) that is involved in complex II of the mitochondrial electron transport chain and is responsible for transferring electrons from succinate to ubiquinone (coenzyme Q).	0.404
ENSONIP00000010953	fdx2	ENSONIP00000010953	ENSONIP00000022765	Apoptosis inducing factor mitochondria associated 5.	Ferredoxin 2.	0.738
FDX1	ENSONIP00000010953	ENSONIP00000015113	ENSONIP00000010953	Ferredoxin 1.	Apoptosis inducing factor mitochondria associated 5.	0.738
FDX1	Fxn	ENSONIP00000015113	ENSONIP00000029150	Ferredoxin 1.	Frataxin, mitochondrial.	0.830
FDX1	Iscu	ENSONIP00000015113	ENSONIP00000016866	Ferredoxin 1.	Iron-sulfur cluster assembly enzyme; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.	0.886
FDX1	LOC100696766	ENSONIP00000015113	ENSONIP00000010260	Ferredoxin 1.	Apoptosis inducing factor mitochondria associated 4.	0.738
FDX1	LOC100698621	ENSONIP00000015113	ENSONIP00000019162	Ferredoxin 1.	Uncharacterized protein; Belongs to the complex I 75 kDa subunit family.	0.547
FDX1	LOC100702604	ENSONIP00000015113	ENSONIP00000016346	Ferredoxin 1.	Zgc:92275.	0.947
FDX1	LOC100705178	ENSONIP00000015113	ENSONIP00000017501	Ferredoxin 1.	Iron-sulfur cluster assembly enzyme b; Scaffold protein for the de novo synthesis of iron-sulfur (Fe-S) clusters within mitochondria, which is required for maturation of both mitochondrial and cytoplasmic [2Fe-2S] and [4Fe-4S] proteins.	0.886
FDX1	LOC100706616	ENSONIP00000015113	ENSONIP00000027607	Ferredoxin 1.	Uncharacterized protein; Belongs to the BolA/IbaG family.	0.457
FDX1	LOC100707594	ENSONIP00000015113	ENSONIP00000013093	Ferredoxin 1.	Cytochrome b-c1 complex subunit Rieske, mitochondrial; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.	0.743
FDX1	NDUFS1	ENSONIP00000015113	ENSONIP00000056489	Ferredoxin 1.	NADH:ubiquinone oxidoreductase core subunit S1; Belongs to the complex I 75 kDa subunit family.	0.547
FDX1	UQCRFS1	ENSONIP00000015113	ENSONIP00000013092	Ferredoxin 1.	Cytochrome b-c1 complex subunit Rieske, mitochondrial; Component of the ubiquinol-cytochrome c reductase complex (complex III or cytochrome b-c1 complex), which is a respiratory chain that generates an electrochemical potential coupled to ATP synthesis.	0.743