(4 nodes) Positive regulation of glial cell proliferation network (Oreochromis niloticus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC100707066	Interleukin-1. (244 aa)
	LOC100534578	Tumor necrosis factor b (TNF superfamily, member 2). (247 aa)
	vegfc	Vascular endothelial growth factor c; Belongs to the PDGF/VEGF growth factor family. (418 aa)
	mecp2	Methyl CpG binding protein 2. (1076 aa)

Your Current Organism:

Oreochromis niloticus

NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
LOC100534578	LOC100707066	ENSONIP00000002809	ENSONIP00000010489	Tumor necrosis factor b (TNF superfamily, member 2).	Interleukin-1.	0.953
LOC100707066	LOC100534578	ENSONIP00000010489	ENSONIP00000002809	Interleukin-1.	Tumor necrosis factor b (TNF superfamily, member 2).	0.953
LOC100707066	mecp2	ENSONIP00000010489	ENSONIP00000029287	Interleukin-1.	Methyl CpG binding protein 2.	0.607
LOC100707066	vegfc	ENSONIP00000010489	ENSONIP00000025274	Interleukin-1.	Vascular endothelial growth factor c; Belongs to the PDGF/VEGF growth factor family.	0.529
mecp2	LOC100707066	ENSONIP00000029287	ENSONIP00000010489	Methyl CpG binding protein 2.	Interleukin-1.	0.607
vegfc	LOC100707066	ENSONIP00000025274	ENSONIP00000010489	Vascular endothelial growth factor c; Belongs to the PDGF/VEGF growth factor family.	Interleukin-1.	0.529