STRINGSTRING
LOC100707250 LOC100707250 Zranb1 Zranb1 tnfaip3 tnfaip3 tab2 tab2 ENSONIP00000061056 ENSONIP00000061056 ENSONIP00000060526 ENSONIP00000060526 LOC100701166 LOC100701166 otud7b otud7b I3KZL7_ORENI I3KZL7_ORENI sprtn sprtn LOC100691685 LOC100691685 zranb3 zranb3 optn optn prpf8 prpf8 ENSONIP00000008001 ENSONIP00000008001 tab3 tab3 Atrip Atrip ZRANB1 ZRANB1 sqstm1 sqstm1
Nodes:
Network nodes represent proteins
splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.
Node Color
colored nodes:
query proteins and first shell of interactors
white nodes:
second shell of interactors
Node Content
empty nodes:
proteins of unknown 3D structure
filled nodes:
a 3D structure is known or predicted
Edges:
Edges represent protein-protein associations
associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.
Known Interactions
from curated databases
experimentally determined
Predicted Interactions
gene neighborhood
gene fusions
gene co-occurrence
Others
textmining
co-expression
protein homology
Your Input:
LOC100707250Uncharacterized protein. (1108 aa)
Zranb1Zinc finger, RAN-binding domain containing 1a. (759 aa)
tnfaip3Tumor necrosis factor, alpha-induced protein 3. (861 aa)
tab2TGF-beta activated kinase 1 (MAP3K7) binding protein 2. (738 aa)
ENSONIP00000061056Poly [ADP-ribose] polymerase 10/14/15. (1031 aa)
ENSONIP00000060526Si:dkey-181m9.8. (507 aa)
LOC100701166OTU deubiquitinase 7A. (958 aa)
otud7bOTU deubiquitinase 7B. (920 aa)
I3KZL7_ORENIZinc finger and BTB domain containing 1. (727 aa)
sprtnSprT-like N-terminal domain. (499 aa)
LOC100691685E3 ubiquitin-protein ligase RNF168; E3 ubiquitin-protein ligase required for accumulation of repair proteins to sites of DNA damage. Acts with UBE2N/UBC13 to amplify the RNF8-dependent histone ubiquitination. Recruited to sites of DNA damage at double-strand breaks (DSBs) by binding to ubiquitinated histone H2A and ubiquitinates histone H2A and H2AX, leading to amplify the RNF8-dependent H2A ubiquitination and promoting the formation of 'Lys-63'-linked ubiquitin conjugates. This leads to concentrate ubiquitinated histones H2A and H2AX at DNA lesions to the threshold required for recrui [...] (442 aa)
zranb3Zinc finger, RAN-binding domain containing 3. (1150 aa)
optnOptineurin. (528 aa)
prpf8Pre-mRNA processing factor 8. (2350 aa)
ENSONIP00000008001E3 ubiquitin-protein ligase RNF31 isoform X1. (1087 aa)
tab3TGF-beta activated kinase 1 (MAP3K7) binding protein 3. (624 aa)
AtripUncharacterized protein. (808 aa)
ZRANB1Zinc finger RANBP2-type containing 1. (799 aa)
sqstm1Sequestosome 1. (436 aa)
Your Current Organism:
Oreochromis niloticus
NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica
Server load: low (18%) [HD]
STRING is a Core Data Resource as designated by Global Biodata Coalition and ELIXIR.