(34 nodes) Catalytic step 2 spliceosome network (Oreochromis niloticus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	crnkl1	Crooked neck pre-mRNA splicing factor 1. (758 aa)
	dhx35	DEAH-box helicase 35. (706 aa)
	I3JSM1_ORENI	Serine/arginine repetitive matrix 2. (1331 aa)
	DDX41	DEAD-box helicase 41. (614 aa)
	cwc15	CWC15 spliceosome associated protein homolog. (237 aa)
	EFL1	Elongation factor like GTPase 1. (1098 aa)
	eftud2	Elongation factor Tu GTP binding domain containing 2. (1011 aa)
	ppie	Peptidyl-prolyl cis-trans isomerase E; Catalyzes the cis-trans isomerization of proline imidic peptide bonds in proteins; Belongs to the cyclophilin-type PPIase family. PPIase E subfamily. (309 aa)
	snrnp40	Small nuclear ribonucleoprotein 40 (U5). (347 aa)
	aqr	Aquarius intron-binding spliceosomal factor. (1473 aa)
	LOC100708824	RRM domain-containing protein. (396 aa)
	prpf4b	Pre-mRNA processing factor 4Bb. (1020 aa)
	dhx38	DEAH (Asp-Glu-Ala-His) box polypeptide 38. (1261 aa)
	xab2	XPA binding protein 2. (854 aa)
	ppil3	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (167 aa)
	ddx23	DEAD (Asp-Glu-Ala-Asp) box polypeptide 23. (834 aa)
	ppwd1	Peptidylprolyl isomerase domain and WD repeat containing 1. (643 aa)
	wdr83	WD repeat domain containing 83. (319 aa)
	LOC109194311	RRM domain-containing protein. (319 aa)
	ppil1	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family. (202 aa)
	ess2	Ess-2 splicing factor homolog. (476 aa)
	cdc40	Cell division cycle 40 homolog (S. cerevisiae). (581 aa)
	Sart3	Spliceosome associated factor 3, U4/U6 recycling protein. (997 aa)
	rbm22	RNA binding motif protein 22. (427 aa)
	snrnp200	Small nuclear ribonucleoprotein 200 (U5). (2136 aa)
	cactin	Cactin. (875 aa)
	srrm1	Serine/arginine repetitive matrix 1. (867 aa)
	mtrex	Mtr4 exosome RNA helicase. (1037 aa)
	Cwc22	MI domain-containing protein. (1025 aa)
	mthfsd	Methenyltetrahydrofolate synthetase domain containing. (480 aa)
	WDR25	WD repeat domain 25. (503 aa)
	gpatch1	G patch domain containing 1. (992 aa)
	rbmx	RNA binding motif protein X-linked. (391 aa)
	snw1	SNW domain containing 1. (536 aa)

Your Current Organism:

Oreochromis niloticus

NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
Cwc22	DDX41	ENSONIP00000008688	ENSONIP00000069776	MI domain-containing protein.	DEAD-box helicase 41.	0.665
Cwc22	EFL1	ENSONIP00000008688	ENSONIP00000063931	MI domain-containing protein.	Elongation factor like GTPase 1.	0.771
Cwc22	I3JSM1_ORENI	ENSONIP00000008688	ENSONIP00000072810	MI domain-containing protein.	Serine/arginine repetitive matrix 2.	0.968
Cwc22	WDR25	ENSONIP00000008688	ENSONIP00000004471	MI domain-containing protein.	WD repeat domain 25.	0.961
Cwc22	aqr	ENSONIP00000008688	ENSONIP00000051878	MI domain-containing protein.	Aquarius intron-binding spliceosomal factor.	0.852
Cwc22	cactin	ENSONIP00000008688	ENSONIP00000012869	MI domain-containing protein.	Cactin.	0.836
Cwc22	cdc40	ENSONIP00000008688	ENSONIP00000016887	MI domain-containing protein.	Cell division cycle 40 homolog (S. cerevisiae).	0.999
Cwc22	crnkl1	ENSONIP00000008688	ENSONIP00000072834	MI domain-containing protein.	Crooked neck pre-mRNA splicing factor 1.	0.977
Cwc22	cwc15	ENSONIP00000008688	ENSONIP00000064198	MI domain-containing protein.	CWC15 spliceosome associated protein homolog.	0.931
Cwc22	ddx23	ENSONIP00000008688	ENSONIP00000039690	MI domain-containing protein.	DEAD (Asp-Glu-Ala-Asp) box polypeptide 23.	0.771
Cwc22	dhx35	ENSONIP00000008688	ENSONIP00000075139	MI domain-containing protein.	DEAH-box helicase 35.	0.916
Cwc22	dhx38	ENSONIP00000008688	ENSONIP00000048005	MI domain-containing protein.	DEAH (Asp-Glu-Ala-His) box polypeptide 38.	0.993
Cwc22	eftud2	ENSONIP00000008688	ENSONIP00000055002	MI domain-containing protein.	Elongation factor Tu GTP binding domain containing 2.	0.994
Cwc22	ess2	ENSONIP00000008688	ENSONIP00000017494	MI domain-containing protein.	Ess-2 splicing factor homolog.	0.482
Cwc22	gpatch1	ENSONIP00000008688	ENSONIP00000004149	MI domain-containing protein.	G patch domain containing 1.	0.739
Cwc22	mtrex	ENSONIP00000008688	ENSONIP00000009566	MI domain-containing protein.	Mtr4 exosome RNA helicase.	0.941
Cwc22	ppie	ENSONIP00000008688	ENSONIP00000054207	MI domain-containing protein.	Peptidyl-prolyl cis-trans isomerase E; Catalyzes the cis-trans isomerization of proline imidic peptide bonds in proteins; Belongs to the cyclophilin-type PPIase family. PPIase E subfamily.	0.741
Cwc22	ppil1	ENSONIP00000008688	ENSONIP00000018120	MI domain-containing protein.	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.	0.967
Cwc22	ppil3	ENSONIP00000008688	ENSONIP00000041138	MI domain-containing protein.	Peptidyl-prolyl cis-trans isomerase; PPIases accelerate the folding of proteins. It catalyzes the cis-trans isomerization of proline imidic peptide bonds in oligopeptides; Belongs to the cyclophilin-type PPIase family.	0.954
Cwc22	ppwd1	ENSONIP00000008688	ENSONIP00000036738	MI domain-containing protein.	Peptidylprolyl isomerase domain and WD repeat containing 1.	0.972