(11 nodes) Peptidase S8/S53 domain network (Oreochromis niloticus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	pcsk1	Proprotein convertase subtilisin/kexin type 1; Belongs to the peptidase S8 family. (774 aa)
	pcsk7	Proprotein convertase subtilisin/kexin type 7; Belongs to the peptidase S8 family. (781 aa)
	tpp2	Tripeptidyl peptidase 2. (1277 aa)
	I3JKW5_ORENI	Proprotein convertase subtilisin/kexin type 5a. (1621 aa)
	furin	Furin (paired basic amino acid cleaving enzyme) b; Belongs to the peptidase S8 family. (843 aa)
	tpp1	Tripeptidyl peptidase I. (563 aa)
	LOC100705046	Furin (paired basic amino acid cleaving enzyme) a; Belongs to the peptidase S8 family. (812 aa)
	pcsk2	Proprotein convertase subtilisin/kexin type 2; Belongs to the peptidase S8 family. (646 aa)
	mbtps1	Membrane-bound transcription factor peptidase, site 1. (1082 aa)
	pcsk9	Proprotein convertase subtilisin/kexin type 9; Belongs to the peptidase S8 family. (669 aa)
	pcsk5	Proprotein convertase subtilisin/kexin type 5b; Belongs to the peptidase S8 family. (1755 aa)

Your Current Organism:

Oreochromis niloticus

NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica

Send network to Cytoscape

Export your current network:

... as a bitmap image:

download

file format is 'PNG': portable network graphic

... as a high-resolution bitmap:

download

same PNG format, but at higher resolution

... as a vector graphic:

download

SVG: scalable vector graphic - can be opened and edited in Illustrator, CorelDraw, Dia, etc

... as short tabular text output:

download

TSV: tab separated values - can be opened in Excel and Cytoscape (lists only one-way edges: A-B)

... as tabular text output:

download

TSV: tab separated values - can be opened in Excel (lists reciprocal edges: A-B,B-A)

... as an XML summary:

download

structured XML interaction data, according to the 'PSI-MI' data standard

... protein node degrees:

download

node degree of proteins in your network (given the current score cut-off)

... network coordinates:

download

a flat-file format describing the coordinates and colors of nodes in the network

... protein sequences:

download

MFA: multi-fasta format - containing the aminoacid sequences in the network

... protein annotations:

download

a tab-delimited file describing the names, domains and descriptions of proteins in your network

... functional annotations:

download

a tab-delimited file containing all known functional terms of proteins in your network

Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
I3JKW5_ORENI	mbtps1	ENSONIP00000038773	ENSONIP00000036408	Proprotein convertase subtilisin/kexin type 5a.	Membrane-bound transcription factor peptidase, site 1.	0.628
mbtps1	I3JKW5_ORENI	ENSONIP00000036408	ENSONIP00000038773	Membrane-bound transcription factor peptidase, site 1.	Proprotein convertase subtilisin/kexin type 5a.	0.628
mbtps1	pcsk5	ENSONIP00000036408	ENSONIP00000016627	Membrane-bound transcription factor peptidase, site 1.	Proprotein convertase subtilisin/kexin type 5b; Belongs to the peptidase S8 family.	0.628
mbtps1	pcsk7	ENSONIP00000036408	ENSONIP00000064875	Membrane-bound transcription factor peptidase, site 1.	Proprotein convertase subtilisin/kexin type 7; Belongs to the peptidase S8 family.	0.572
pcsk5	mbtps1	ENSONIP00000016627	ENSONIP00000036408	Proprotein convertase subtilisin/kexin type 5b; Belongs to the peptidase S8 family.	Membrane-bound transcription factor peptidase, site 1.	0.628
pcsk7	mbtps1	ENSONIP00000064875	ENSONIP00000036408	Proprotein convertase subtilisin/kexin type 7; Belongs to the peptidase S8 family.	Membrane-bound transcription factor peptidase, site 1.	0.572
pcsk7	pcsk9	ENSONIP00000064875	ENSONIP00000003541	Proprotein convertase subtilisin/kexin type 7; Belongs to the peptidase S8 family.	Proprotein convertase subtilisin/kexin type 9; Belongs to the peptidase S8 family.	0.584
pcsk9	pcsk7	ENSONIP00000003541	ENSONIP00000064875	Proprotein convertase subtilisin/kexin type 9; Belongs to the peptidase S8 family.	Proprotein convertase subtilisin/kexin type 7; Belongs to the peptidase S8 family.	0.584