(117 nodes) Small GTPase network (Oreochromis niloticus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	LOC100694008	RASD family member 3. (216 aa)
	LOC100704818	Uncharacterized protein. (347 aa)
	LOC100697822	Uncharacterized protein. (215 aa)
	REM1	RRAD and GEM like GTPase 1. (308 aa)
	LOC100710919	Rho family GTPase 2. (234 aa)
	LOC100707435	DIRAS family, GTP-binding RAS-like 1b. (198 aa)
	LOC100693096	Zgc:171704. (214 aa)
	LOC100706302	RAB11a, member RAS oncogene family, like. (216 aa)
	rab25	RAB25, member RAS oncogene family b. (207 aa)
	LOC100697758	Uncharacterized protein. (218 aa)
	RAB41	RAB41, member RAS oncogene family. (219 aa)
	I3J455_ORENI	Uncharacterized protein. (281 aa)
	rasl11b	RAS-like, family 11, member B. (248 aa)
	rrad	Ras-related associated with diabetes. (309 aa)
	LOC100692392	Uncharacterized protein. (226 aa)
	LOC100691191	Uncharacterized protein. (242 aa)
	LOC100704913	Uncharacterized protein. (200 aa)
	rab18	RAB18A, member RAS oncogene family. (204 aa)
	RALB	RAS like proto-oncogene B. (207 aa)
	LOC100710886	Rho GTPase activating protein 35b. (1529 aa)
	mras	Muscle RAS oncogene homolog. (208 aa)
	LOC100699836	RAB38b, member of RAS oncogene family. (218 aa)
	RAB38	RAB38, member RAS oncogene family. (212 aa)
	rab30	RAB30, member RAS oncogene family. (203 aa)
	LOC100706225	RAB4B, member RAS oncogene family. (232 aa)
	gem	GTP binding protein overexpressed in skeletal muscle. (307 aa)
	rras2	RAS related 2. (202 aa)
	LOC100705444	Uncharacterized protein. (189 aa)
	LOC100705703	Uncharacterized protein. (190 aa)
	LOC100710609	Zgc:162171. (230 aa)
	rab39b	Uncharacterized protein. (213 aa)
	LOC100706493	Uncharacterized protein. (199 aa)
	LOC100699786	RAS related. (196 aa)
	LOC100703329	RAB3D, member RAS oncogene family, b. (225 aa)
	LOC100703328	Si:dkey-16l2.16. (208 aa)
	rab40c	RAB40c, member RAS oncogene family. (279 aa)
	rab23	RAB23, member RAS oncogene family. (235 aa)
	rerg	RAS like estrogen regulated growth inhibitor. (200 aa)
	LOC100689790	RAB33B, member RAS oncogene family a. (240 aa)
	rasl11a	RAS-like, family 11, member A. (255 aa)
	LOC100700106	Uncharacterized protein. (222 aa)
	LOC100700914	RAB15, member RAS oncogene family. (211 aa)
	LOC100693083	Uncharacterized protein. (193 aa)
	I3K382_ORENI	Uncharacterized protein. (201 aa)
	rab27b	RAB27B, member RAS oncogene family. (225 aa)
	rasl10a	RAS-like, family 10, member A. (203 aa)
	LOC100697826	RAB5B, member RAS oncogene family. (303 aa)
	ift27	Intraflagellar transport 27 homolog (Chlamydomonas). (217 aa)
	LOC100708930	ArfGAP with GTPase domain, ankyrin repeat and PH domain 1. (1192 aa)
	rhobtb2	Rho related BTB domain containing 2a. (721 aa)
	arhgap35	Uncharacterized protein. (1549 aa)
	LOC100707666	Uncharacterized protein. (204 aa)
	RAB39B	RAB39B, member RAS oncogene family. (213 aa)
	LOC100695098	ZRAB1B, member RAS oncogene family a. (201 aa)
	LOC100708531	RAB38c, member of RAS oncogene family. (231 aa)
	LOC100697392	V-ral simian leukemia viral oncogene homolog Aa (ras related). (199 aa)
	agap3	ArfGAP with GTPase domain, ankyrin repeat and PH domain 3. (1335 aa)
	RAB11A	RAB11A, member RAS oncogene family. (215 aa)
	LOC100703836	Zgc:55558. (250 aa)
	LOC100702459	Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family. (709 aa)
	rhoq	Ras homolog family member Q. (207 aa)
	rab24	RAB24, member RAS oncogene family. (205 aa)
	LOC100704868	RAB5A, member RAS oncogene family, b. (217 aa)
	I3KT57_ORENI	RAB6B, member RAS oncogene family a. (231 aa)
	LOC100698785	Uncharacterized protein. (193 aa)
	rab13	RAB13, member RAS oncogene family. (200 aa)
	LOC100694510	Calcium release activated channel regulator 2A. (721 aa)
	rab22a	RAB22A, member RAS oncogene family. (210 aa)
	rhot2	Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family. (647 aa)
	LOC100704372	Ras homolog family member F. (208 aa)
	RAB28	RAB28, member RAS oncogene family. (222 aa)
	LOC100707445	Uncharacterized protein. (193 aa)
	cdc42	Cell division cycle 42. (209 aa)
	LOC100690483	Mitochondrial Rho GTPase; Mitochondrial GTPase involved in mitochondrial trafficking. Belongs to the mitochondrial Rho GTPase family. (684 aa)
	rab8a	RAB8A, member RAS oncogene family. (209 aa)
	rab3a	RAB3A, member RAS oncogene family, b. (219 aa)
	LOC100706208	Calcium release activated channel regulator 2Ab. (779 aa)
	LOC100694171	RAB3B, member RAS oncogene family. (217 aa)
	LOC100707935	Rho related BTB domain containing 4. (745 aa)
	ran	GTP-binding nuclear protein Ran; GTP-binding protein involved in nucleocytoplasmic transport. Required for the import of protein into the nucleus and also for RNA export. Involved in chromatin condensation and control of cell cycle. Belongs to the small GTPase superfamily. Ran family. (260 aa)
	Dnajc27	DnaJ (Hsp40) homolog, subfamily C, member 27. (306 aa)
	RND2	Rho family GTPase 2. (243 aa)
	rab6a	RAB6A, member RAS oncogene family. (211 aa)
	I3J0X9_ORENI	RASD family member 2. (324 aa)
	rhoh	Ras homolog family member H. (188 aa)
	LOC100700404	Rasd family member 4. (208 aa)
	I3KZI5_ORENI	Uncharacterized protein. (208 aa)
	LOC100700420	Uncharacterized protein. (203 aa)
	RAB9A	RAB9A, member RAS oncogene family. (202 aa)
	RAP2B	RAP2B, member of RAS oncogene family. (183 aa)
	LOC100698667	Ras homolog gene family, member Gd. (191 aa)
	LOC100697336	RAB9B, member RAS oncogene family. (202 aa)
	I3KWS8_ORENI	Si:dkey-13a21.4. (204 aa)
	RAC1	Rac family small GTPase 1. (201 aa)
	rasd1	RAS, dexamethasone-induced 1. (371 aa)
	RAB37	RAB37, member RAS oncogene family. (244 aa)
	LOC100706499	Uncharacterized protein. (228 aa)
	AGAP2	ArfGAP with GTPase domain, ankyrin repeat and PH domain 2. (1220 aa)
	LOC100710477	Ras homolog gene family, member Ab. (193 aa)
	RAB40C	RAB40C, member RAS oncogene family. (292 aa)
	LOC100703352	RAB8A, member RAS oncogene family. (206 aa)
	rab21	RAB21, member RAS oncogene family. (233 aa)
	rap1b	Uncharacterized protein. (185 aa)
	rab4a	RAB4a, member RAS oncogene family. (213 aa)
	I3KK64_ORENI	Uncharacterized protein. (278 aa)
	RAC2	Rac family small GTPase 2. (205 aa)
	LOC100706684	Uncharacterized protein. (250 aa)
	RAB17	RAB17, member RAS oncogene family. (227 aa)
	I3KIA3_ORENI	ArfGAP with GTPase domain, ankyrin repeat and PH domain 2. (1199 aa)
	LOC100694617	Si:dkey-27j5.5. (390 aa)
	LOC100706267	Uncharacterized protein. (222 aa)
	rergl	Uncharacterized protein. (205 aa)
	LOC100703655	Zgc:110699. (198 aa)
	LOC100692867	Zgc:162879. (664 aa)
	rasef	RAS and EF-hand domain containing. (813 aa)
	LOC100700981	RAB, member of RAS oncogene family-like 2. (210 aa)
	kras	V-Ki-ras2 Kirsten rat sarcoma viral oncogene homolog. (189 aa)

Your Current Organism:

Oreochromis niloticus

NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AGAP2	I3KIA3_ORENI	ENSONIP00000024141	ENSONIP00000020848	ArfGAP with GTPase domain, ankyrin repeat and PH domain 2.	ArfGAP with GTPase domain, ankyrin repeat and PH domain 2.	0.903
Dnajc27	I3KT57_ORENI	ENSONIP00000031122	ENSONIP00000056723	DnaJ (Hsp40) homolog, subfamily C, member 27.	RAB6B, member RAS oncogene family a.	0.414
Dnajc27	I3KWS8_ORENI	ENSONIP00000031122	ENSONIP00000025574	DnaJ (Hsp40) homolog, subfamily C, member 27.	Si:dkey-13a21.4.	0.420
Dnajc27	LOC100689790	ENSONIP00000031122	ENSONIP00000014559	DnaJ (Hsp40) homolog, subfamily C, member 27.	RAB33B, member RAS oncogene family a.	0.427
Dnajc27	LOC100691191	ENSONIP00000031122	ENSONIP00000004240	DnaJ (Hsp40) homolog, subfamily C, member 27.	Uncharacterized protein.	0.442
Dnajc27	LOC100695098	ENSONIP00000031122	ENSONIP00000072355	DnaJ (Hsp40) homolog, subfamily C, member 27.	ZRAB1B, member RAS oncogene family a.	0.409
Dnajc27	LOC100697336	ENSONIP00000031122	ENSONIP00000025886	DnaJ (Hsp40) homolog, subfamily C, member 27.	RAB9B, member RAS oncogene family.	0.421
Dnajc27	LOC100697822	ENSONIP00000031122	ENSONIP00000000709	DnaJ (Hsp40) homolog, subfamily C, member 27.	Uncharacterized protein.	0.472
Dnajc27	LOC100700420	ENSONIP00000031122	ENSONIP00000026248	DnaJ (Hsp40) homolog, subfamily C, member 27.	Uncharacterized protein.	0.420
Dnajc27	LOC100707666	ENSONIP00000031122	ENSONIP00000075373	DnaJ (Hsp40) homolog, subfamily C, member 27.	Uncharacterized protein.	0.409
Dnajc27	RAB41	ENSONIP00000031122	ENSONIP00000003479	DnaJ (Hsp40) homolog, subfamily C, member 27.	RAB41, member RAS oncogene family.	0.414
Dnajc27	RAB9A	ENSONIP00000031122	ENSONIP00000025980	DnaJ (Hsp40) homolog, subfamily C, member 27.	RAB9A, member RAS oncogene family.	0.422
Dnajc27	rab18	ENSONIP00000031122	ENSONIP00000004684	DnaJ (Hsp40) homolog, subfamily C, member 27.	RAB18A, member RAS oncogene family.	0.527
Dnajc27	rab30	ENSONIP00000031122	ENSONIP00000007192	DnaJ (Hsp40) homolog, subfamily C, member 27.	RAB30, member RAS oncogene family.	0.419
Dnajc27	rab6a	ENSONIP00000031122	ENSONIP00000029395	DnaJ (Hsp40) homolog, subfamily C, member 27.	RAB6A, member RAS oncogene family.	0.414
I3K382_ORENI	I3KK64_ORENI	ENSONIP00000015577	ENSONIP00000021509	Uncharacterized protein.	Uncharacterized protein.	0.419
I3K382_ORENI	LOC100698667	ENSONIP00000015577	ENSONIP00000025887	Uncharacterized protein.	Ras homolog gene family, member Gd.	0.419
I3K382_ORENI	LOC100705444	ENSONIP00000015577	ENSONIP00000008814	Uncharacterized protein.	Uncharacterized protein.	0.438
I3K382_ORENI	LOC100705703	ENSONIP00000015577	ENSONIP00000008815	Uncharacterized protein.	Uncharacterized protein.	0.452
I3K382_ORENI	LOC100710886	ENSONIP00000015577	ENSONIP00000005508	Uncharacterized protein.	Rho GTPase activating protein 35b.	0.651