(12 nodes) Post-SET domain network (Oreochromis niloticus)

Nodes:

Network nodes represent proteins

splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

Node Color

colored nodes:
query proteins and first shell of interactors

white nodes:
second shell of interactors

Node Content

empty nodes:
proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

Edges:

Edges represent protein-protein associations

associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

from curated databases

experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	kmt2b	Lysine (K)-specific methyltransferase 2Bb. (3861 aa)
	I3K397_ORENI	Nuclear receptor binding SET domain protein 2. (1109 aa)
	LOC100692734	Nuclear receptor binding SET domain protein 1a. (2550 aa)
	LOC100707110	Ash1 (absent, small, or homeotic)-like (Drosophila). (2966 aa)
	I3KAI1_ORENI	Nuclear receptor binding SET domain protein 3. (1446 aa)
	LOC100692647	SET domain containing 1B, histone lysine methyltransferase a. (1811 aa)
	kmt2d	Lysine (K)-specific methyltransferase 2D. (5041 aa)
	suv39h1	Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. Suvar3-9 subfamily. (411 aa)
	I3JTS7_ORENI	Lysine (K)-specific methyltransferase 2Cb. (417 aa)
	setdb1	SET domain bifurcated histone lysine methyltransferase 1b. (1230 aa)
	KMT2A	Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. TRX/MLL subfamily. (4124 aa)
	setd2	SET domain containing 2, histone lysine methyltransferase. (2602 aa)

Your Current Organism:

Oreochromis niloticus

NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
I3JTS7_ORENI	I3KAI1_ORENI	ENSONIP00000012272	ENSONIP00000018125	Lysine (K)-specific methyltransferase 2Cb.	Nuclear receptor binding SET domain protein 3.	0.426
I3JTS7_ORENI	KMT2A	ENSONIP00000012272	ENSONIP00000007849	Lysine (K)-specific methyltransferase 2Cb.	Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. TRX/MLL subfamily.	0.580
I3JTS7_ORENI	LOC100692647	ENSONIP00000012272	ENSONIP00000017473	Lysine (K)-specific methyltransferase 2Cb.	SET domain containing 1B, histone lysine methyltransferase a.	0.648
I3JTS7_ORENI	kmt2b	ENSONIP00000012272	ENSONIP00000003450	Lysine (K)-specific methyltransferase 2Cb.	Lysine (K)-specific methyltransferase 2Bb.	0.580
I3K397_ORENI	LOC100707110	ENSONIP00000058247	ENSONIP00000024817	Nuclear receptor binding SET domain protein 2.	Ash1 (absent, small, or homeotic)-like (Drosophila).	0.483
I3KAI1_ORENI	I3JTS7_ORENI	ENSONIP00000018125	ENSONIP00000012272	Nuclear receptor binding SET domain protein 3.	Lysine (K)-specific methyltransferase 2Cb.	0.426
I3KAI1_ORENI	LOC100692647	ENSONIP00000018125	ENSONIP00000017473	Nuclear receptor binding SET domain protein 3.	SET domain containing 1B, histone lysine methyltransferase a.	0.503
I3KAI1_ORENI	kmt2d	ENSONIP00000018125	ENSONIP00000015272	Nuclear receptor binding SET domain protein 3.	Lysine (K)-specific methyltransferase 2D.	0.426
KMT2A	I3JTS7_ORENI	ENSONIP00000007849	ENSONIP00000012272	Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. TRX/MLL subfamily.	Lysine (K)-specific methyltransferase 2Cb.	0.580
KMT2A	LOC100692647	ENSONIP00000007849	ENSONIP00000017473	Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. TRX/MLL subfamily.	SET domain containing 1B, histone lysine methyltransferase a.	0.601
KMT2A	LOC100707110	ENSONIP00000007849	ENSONIP00000024817	Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. TRX/MLL subfamily.	Ash1 (absent, small, or homeotic)-like (Drosophila).	0.508
KMT2A	kmt2d	ENSONIP00000007849	ENSONIP00000015272	Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. TRX/MLL subfamily.	Lysine (K)-specific methyltransferase 2D.	0.580
LOC100692647	I3JTS7_ORENI	ENSONIP00000017473	ENSONIP00000012272	SET domain containing 1B, histone lysine methyltransferase a.	Lysine (K)-specific methyltransferase 2Cb.	0.648
LOC100692647	I3KAI1_ORENI	ENSONIP00000017473	ENSONIP00000018125	SET domain containing 1B, histone lysine methyltransferase a.	Nuclear receptor binding SET domain protein 3.	0.503
LOC100692647	KMT2A	ENSONIP00000017473	ENSONIP00000007849	SET domain containing 1B, histone lysine methyltransferase a.	Histone-lysine N-methyltransferase; Belongs to the class V-like SAM-binding methyltransferase superfamily. Histone-lysine methyltransferase family. TRX/MLL subfamily.	0.601
LOC100692647	kmt2b	ENSONIP00000017473	ENSONIP00000003450	SET domain containing 1B, histone lysine methyltransferase a.	Lysine (K)-specific methyltransferase 2Bb.	0.601
LOC100692647	kmt2d	ENSONIP00000017473	ENSONIP00000015272	SET domain containing 1B, histone lysine methyltransferase a.	Lysine (K)-specific methyltransferase 2D.	0.648
LOC100692647	setd2	ENSONIP00000017473	ENSONIP00000003855	SET domain containing 1B, histone lysine methyltransferase a.	SET domain containing 2, histone lysine methyltransferase.	0.798
LOC100692734	kmt2b	ENSONIP00000036851	ENSONIP00000003450	Nuclear receptor binding SET domain protein 1a.	Lysine (K)-specific methyltransferase 2Bb.	0.412
LOC100692734	setd2	ENSONIP00000036851	ENSONIP00000003855	Nuclear receptor binding SET domain protein 1a.	SET domain containing 2, histone lysine methyltransferase.	0.504