(13 nodes) Clathrin adaptor, appendage, Ig-like subdomain superfamily network (Oreochromis niloticus)

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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Known Interactions

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Predicted Interactions

gene neighborhood

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Your Input:
	copg2	Coatomer subunit gamma; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins. (932 aa)
	LOC100697104	Uncharacterized protein. (610 aa)
	LOC100707472	AP complex subunit beta. (953 aa)
	LOC100694605	Golgi associated, gamma adaptin ear containing, ARF binding protein 3a. (752 aa)
	ap1b1	AP complex subunit beta. (1001 aa)
	LOC100692916	Golgi associated, gamma adaptin ear containing, ARF binding protein 1. (662 aa)
	AP3B2	AP-3 complex subunit beta. (1230 aa)
	LOC100694377	AP-1 complex subunit gamma. (789 aa)
	gga3	Golgi associated, gamma adaptin ear containing, ARF binding protein 3b. (727 aa)
	ap1g1	AP-1 complex subunit gamma. (823 aa)
	LOC100700052	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (965 aa)
	I3JNW5_ORENI	Uncharacterized protein. (633 aa)
	LOC100696314	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...] (994 aa)

Your Current Organism:

Oreochromis niloticus

NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
AP3B2	LOC100694377	ENSONIP00000048400	ENSONIP00000048943	AP-3 complex subunit beta.	AP-1 complex subunit gamma.	0.894
AP3B2	LOC100700052	ENSONIP00000048400	ENSONIP00000061455	AP-3 complex subunit beta.	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	0.852
AP3B2	LOC100707472	ENSONIP00000048400	ENSONIP00000021924	AP-3 complex subunit beta.	AP complex subunit beta.	0.735
AP3B2	ap1b1	ENSONIP00000048400	ENSONIP00000042829	AP-3 complex subunit beta.	AP complex subunit beta.	0.735
AP3B2	ap1g1	ENSONIP00000048400	ENSONIP00000054543	AP-3 complex subunit beta.	AP-1 complex subunit gamma.	0.894
LOC100694377	AP3B2	ENSONIP00000048943	ENSONIP00000048400	AP-1 complex subunit gamma.	AP-3 complex subunit beta.	0.894
LOC100694377	LOC100694605	ENSONIP00000048943	ENSONIP00000022843	AP-1 complex subunit gamma.	Golgi associated, gamma adaptin ear containing, ARF binding protein 3a.	0.444
LOC100694377	LOC100700052	ENSONIP00000048943	ENSONIP00000061455	AP-1 complex subunit gamma.	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	0.522
LOC100694377	LOC100707472	ENSONIP00000048943	ENSONIP00000021924	AP-1 complex subunit gamma.	AP complex subunit beta.	0.954
LOC100694377	ap1b1	ENSONIP00000048943	ENSONIP00000042829	AP-1 complex subunit gamma.	AP complex subunit beta.	0.992
LOC100694377	ap1g1	ENSONIP00000048943	ENSONIP00000054543	AP-1 complex subunit gamma.	AP-1 complex subunit gamma.	0.901
LOC100694377	copg2	ENSONIP00000048943	ENSONIP00000014601	AP-1 complex subunit gamma.	Coatomer subunit gamma; The coatomer is a cytosolic protein complex that binds to dilysine motifs and reversibly associates with Golgi non-clathrin- coated vesicles, which further mediate biosynthetic protein transport from the ER, via the Golgi up to the trans Golgi network. Coatomer complex is required for budding from Golgi membranes, and is essential for the retrograde Golgi-to-ER transport of dilysine-tagged proteins.	0.415
LOC100694377	gga3	ENSONIP00000048943	ENSONIP00000002802	AP-1 complex subunit gamma.	Golgi associated, gamma adaptin ear containing, ARF binding protein 3b.	0.444
LOC100694605	LOC100694377	ENSONIP00000022843	ENSONIP00000048943	Golgi associated, gamma adaptin ear containing, ARF binding protein 3a.	AP-1 complex subunit gamma.	0.444
LOC100694605	ap1g1	ENSONIP00000022843	ENSONIP00000054543	Golgi associated, gamma adaptin ear containing, ARF binding protein 3a.	AP-1 complex subunit gamma.	0.444
LOC100696314	LOC100700052	ENSONIP00000068668	ENSONIP00000061455	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	0.691
LOC100696314	LOC100707472	ENSONIP00000068668	ENSONIP00000021924	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	AP complex subunit beta.	0.994
LOC100696314	ap1b1	ENSONIP00000068668	ENSONIP00000042829	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	AP complex subunit beta.	0.965
LOC100700052	AP3B2	ENSONIP00000061455	ENSONIP00000048400	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	AP-3 complex subunit beta.	0.852
LOC100700052	LOC100694377	ENSONIP00000061455	ENSONIP00000048943	AP-2 complex subunit alpha; Component of the adaptor protein complex 2 (AP-2). Adaptor protein complexes function in protein transport via transport vesicles in different membrane traffic pathways. Adaptor protein complexes are vesicle coat components and appear to be involved in cargo selection and vesicle formation. AP-2 is involved in clathrin-dependent endocytosis in which cargo proteins are incorporated into vesicles surrounded by clathrin (clathrin-coated vesicles, CCVs) which are destined for fusion with the early endosome. The clathrin lattice serves as a mechanical scaffold bu [...]	AP-1 complex subunit gamma.	0.522