(12 nodes) Histidine phosphatase superfamily, clade-1 network (Oreochromis niloticus)

Nodes:

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splice isoforms or post-translational modifications are collapsed, i.e. each node represents all the proteins produced by a single, protein-coding gene locus.

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query proteins and first shell of interactors

white nodes:
second shell of interactors

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proteins of unknown 3D structure

filled nodes:
a 3D structure is known or predicted

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associations are meant to be specific and meaningful, i.e. proteins jointly contribute to a shared function; this does not necessarily mean they are physically binding to each other.

Known Interactions

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experimentally determined

Predicted Interactions

gene neighborhood

gene fusions

gene co-occurrence

Others

textmining

co-expression

protein homology

Your Input:
	pgam5	PGAM family member 5, serine/threonine protein phosphatase, mitochondrial. (300 aa)
	LOC106096811	Ubiquitin associated and SH3 domain containing Bb. (652 aa)
	LOC100712280	6PF2K domain-containing protein. (536 aa)
	I3J820_ORENI	Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (264 aa)
	I3KS66_ORENI	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4b. (532 aa)
	LOC100703776	6PF2K domain-containing protein. (546 aa)
	I3JD76_ORENI	Ubiquitin associated and SH3 domain containing Ba. (652 aa)
	LOC100700435	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1. (527 aa)
	LOC100703249	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4a. (530 aa)
	pfkfb3	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3. (534 aa)
	I3ITT0_ORENI	TP53 induced glycolysis regulatory phosphatase b. (318 aa)
	LOC100692737	Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily. (254 aa)

Your Current Organism:

Oreochromis niloticus

NCBI taxonomy Id: 8128
Other names: Nile tilapia, O. niloticus, Oreochromis nilotica, Tilapia nilotica

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Browse interactions in tabular form:

node1	node2	node1 accession	node2 accession	node1 annotation	node2 annotation	score
I3ITT0_ORENI	I3KS66_ORENI	ENSONIP00000000019	ENSONIP00000037421	TP53 induced glycolysis regulatory phosphatase b.	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4b.	0.407
I3ITT0_ORENI	LOC100700435	ENSONIP00000000019	ENSONIP00000069839	TP53 induced glycolysis regulatory phosphatase b.	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1.	0.938
I3ITT0_ORENI	LOC100703249	ENSONIP00000000019	ENSONIP00000066002	TP53 induced glycolysis regulatory phosphatase b.	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4a.	0.407
I3ITT0_ORENI	LOC100703776	ENSONIP00000000019	ENSONIP00000034816	TP53 induced glycolysis regulatory phosphatase b.	6PF2K domain-containing protein.	0.938
I3ITT0_ORENI	LOC100712280	ENSONIP00000000019	ENSONIP00000018623	TP53 induced glycolysis regulatory phosphatase b.	6PF2K domain-containing protein.	0.938
I3ITT0_ORENI	pfkfb3	ENSONIP00000000019	ENSONIP00000032142	TP53 induced glycolysis regulatory phosphatase b.	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3.	0.938
I3J820_ORENI	LOC100692737	ENSONIP00000005010	ENSONIP00000023123	Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily.	Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily.	0.929
I3J820_ORENI	pgam5	ENSONIP00000005010	ENSONIP00000065888	Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily.	PGAM family member 5, serine/threonine protein phosphatase, mitochondrial.	0.474
I3KS66_ORENI	I3ITT0_ORENI	ENSONIP00000037421	ENSONIP00000000019	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4b.	TP53 induced glycolysis regulatory phosphatase b.	0.407
LOC100692737	I3J820_ORENI	ENSONIP00000023123	ENSONIP00000005010	Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily.	Phosphoglycerate mutase; Belongs to the phosphoglycerate mutase family. BPG- dependent PGAM subfamily.	0.929
LOC100700435	I3ITT0_ORENI	ENSONIP00000069839	ENSONIP00000000019	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1.	TP53 induced glycolysis regulatory phosphatase b.	0.938
LOC100700435	LOC100703776	ENSONIP00000069839	ENSONIP00000034816	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1.	6PF2K domain-containing protein.	0.909
LOC100700435	LOC100712280	ENSONIP00000069839	ENSONIP00000018623	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1.	6PF2K domain-containing protein.	0.901
LOC100700435	pfkfb3	ENSONIP00000069839	ENSONIP00000032142	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1.	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3.	0.910
LOC100703249	I3ITT0_ORENI	ENSONIP00000066002	ENSONIP00000000019	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 4a.	TP53 induced glycolysis regulatory phosphatase b.	0.407
LOC100703776	I3ITT0_ORENI	ENSONIP00000034816	ENSONIP00000000019	6PF2K domain-containing protein.	TP53 induced glycolysis regulatory phosphatase b.	0.938
LOC100703776	LOC100700435	ENSONIP00000034816	ENSONIP00000069839	6PF2K domain-containing protein.	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 1.	0.909
LOC100703776	LOC100712280	ENSONIP00000034816	ENSONIP00000018623	6PF2K domain-containing protein.	6PF2K domain-containing protein.	0.909
LOC100703776	pfkfb3	ENSONIP00000034816	ENSONIP00000032142	6PF2K domain-containing protein.	6-phosphofructo-2-kinase/fructose-2,6-biphosphatase 3.	0.910
LOC100712280	I3ITT0_ORENI	ENSONIP00000018623	ENSONIP00000000019	6PF2K domain-containing protein.	TP53 induced glycolysis regulatory phosphatase b.	0.938